Selection of Optimal Hydrate/Solvate Forms of a Fibrinogen Receptor Antagonist for Solid Dosage Development - Bray, Michelle L.; Jahansouz, Hossain; Kaufman, Michael J. (Pharmaceutical development and technology, 1999)
Keywords: Administration, Oral; Azepines - administration & dosage; Azepines - chemistry; Biological and medical sciences; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Crystallinity; Crystallization; Drug Stability; Fibrinogen receptor antagonist; Fibrinolytic Agents - administration & dosage; Fibrinolytic Agents - chemistry; General pharmacology; Humidity; Hydrate; Hygroscopicity; Medical sciences; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors; Polymorphism; Powder x-ray diffractometry; Solubility; Stability; Sulfonamides - administration & dosage; Sulfonamides - chemistry; Thermogravimetry; X-Ray Diffraction; Hygroscopicity; Pharmaceutical technology; Chemical stability; Fibrinogen; Dosage form; Oral form; Antagonist; Crystalline state; Hydrates; Polymorphism; Biological receptor; Physical structure