Continuous flow chemistry: New strategies for preparative inorganic chemistry

• Published in: Coordination chemistry reviews Vol. 324; pp. 39 - 53
• Main Authors: Zhang, Junyong, Gong, Chunhua, Zeng, Xianghua, Xie, Jingli
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2016
• Subjects: Continuous flow chemistry; Inorganic synthesis; Microreactor; Separation and extraction; Continuous flow chemistry; Microreactor; Inorganic synthesis; Separation and extraction
• ISSN: 0010-8545; 1873-3840
• DOI: 10.1016/j.ccr.2016.06.011

Continuous flow chemistry is a process intensification technology and show great advantage compared to the traditional inorganic synthesis under one-pot solution processing conditions. This review summarizes the application of continuous flow chemistry in the separation and extraction of inorganic compounds and the synthesis of metal–organic frameworks and polyoxometalates. [Display omitted] •Technical characteristics.•Separation and extraction.•Metal–organic frameworks, polyoxometalates and organometallic compounds. Uncovering the unique characters of continuous flow chemistry is an important stepping stone in harnessing its power for technological innovation in preparative inorganic chemistry. Compared to the traditional inorganic synthesis under one-pot solution processing conditions and hydrothermal/solvothermal/ionothermal reactions, continuous flow chemistry is a process intensification technology and is advantageous in precisely controlling reaction rate, increasing and scaling up synthesis, and delivering products with maximum yields. This review summarizes the application of continuous flow chemistry in the separation and extraction of inorganic compounds and the synthesis of metal–organic frameworks, polyoxometalates and organometallic compounds.