Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity - Cimini, Flavia Agata; Arena, Andrea; Barchetta, Ilaria; Tramutola, Antonella; Ceccarelli, Valentina; Lanzillotta, Chiara; Fontana, Mario; Bertoccini, Laura; Leonetti, Frida; Capoccia, Danila; Silecchia, Gianfranco; Di Cristofano, Claudio; et al. (Biochimica et biophysica acta. Molecular basis of disease, 2019)
Keywords: Adult; Bariatric Surgery - methods; Biliverdin reductase-a; Case-Control Studies; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Female; Gene Expression Regulation; Glucose Transporter Type 4 - blood; Glucose Transporter Type 4 - genetics; Glycogen Synthase Kinase 3 beta - blood; Glycogen Synthase Kinase 3 beta - genetics; GTPase-Activating Proteins - blood; GTPase-Activating Proteins - genetics; Humans; Insulin - blood; Insulin Receptor Substrate Proteins - blood; Insulin Receptor Substrate Proteins - genetics; Insulin Resistance - genetics; Insulin signaling; Intra-Abdominal Fat - metabolism; Intra-Abdominal Fat - pathology; Leukocytes, Mononuclear - metabolism; Leukocytes, Mononuclear - pathology; Male; Metabolic disorders; Middle Aged; Obesity; Obesity - blood; Obesity - genetics; Obesity - pathology; Obesity - surgery; Oxidoreductases Acting on CH-CH Group Donors - blood; Oxidoreductases Acting on CH-CH Group Donors - deficiency; Oxidoreductases Acting on CH-CH Group Donors - genetics; Primary Cell Culture; Proto-Oncogene Proteins c-akt - blood; Proto-Oncogene Proteins c-akt - genetics; Signal Transduction - genetics; TOR Serine-Threonine Kinases - blood; TOR Serine-Threonine Kinases - genetics; Triglycerides - blood; Obesity; Metabolic disorders; Biliverdin reductase-a; Insulin signaling