Inverse versus convolution treatment planning algorithms for gamma knife radiosurgery

• Published in: Journal of the Pakistan Medical Association Vol. 74; no. 10 (Supple-08); pp. S278 - S282
• Main Authors: Ghanim, Marwa, Abdullah, Siham, Faraj, Moneer, Alazawy, Nabaa
• Format: Journal Article
• Language: English
• Published: Pakistan Pakistan Medical Association 01.10.2024
• Subjects: Adolescent; Adult; Aged; Algorithms; Brain Neoplasms - diagnostic imaging; Brain Neoplasms - surgery; Child; Cross-Sectional Studies; Female; Humans; Magnetic Resonance Imaging - methods; Male; Meningioma - diagnostic imaging; Meningioma - radiotherapy; Meningioma - surgery; Middle Aged; Radiosurgery - methods; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted - methods; Tomography, X-Ray Computed - methods; Young Adult; Tumour, Algorithms, Brain, Magnetic, Tomography
• ISSN: 0030-9982; 0030-9982
• DOI: 10.47391/JPMA-BAGH-16-63

Objective: To compare the convolution and inverse algorithm plans.Method: The cross-sectional study was conducted from January to May 2022 at the Icon Gamma Knife Centre, Al-Taj Hospital, Baghdad, Iraq, and comprised patients with malignant and benign brain tumours who underwentgamma knife therapy. Each patient's brain was imaged using computed tomography and magnetic resonanceimaging. The neurosurgeon prescribed the dose depending on the tumour volume and type, while the medicalphysicist generated the two plans based on inverse and convolution algorithms. The prescribed dose was deliveredto 50% of the isodose line of the tumour. Each plan was evaluated with respect to tumour conformity index,coverage, gradient index, number of shots, and time of treatment.Results: Of the 30 patients, 17(56.7%) were males and 13(43.3%) were females. The overall mean age was46.29±15.20 years (range: 10-71 years). The mean dose delivered was 15.86±3.86Gy, and the mean number ofgamma radiation shots was 12.56±6.95. There was significant difference between the two algorithm plans for alldosimetric parameters, with the inverse plan providing higher coverage and selectivity than convolution plan, buttaking longer time(p<0.05), while plan was inverse plan better than convolution plan in terms of gradient andconformity (p<0.05).Conclusion: With more extended treatment, the inverse plan was found to have superior selectivity, coverage,gradient index and Paddick conformity index values compared to the convolution plan.Key Words: Tumour, Algorithms, Brain, Magnetic, Tomography