Temporal Modulation Transfer Function of Vision by Pattern Visual Evoked Potentials in Patients with Optic Neuritis

• Published in: Ophthalmologica (Basel) Vol. 207; no. 2; pp. 94 - 99
• Main Authors: Abe, Haruki, Hasegawa, Shigeru, Takagi, Mineo, Yoshizawa, Toyohisa, Usui, Tomoaki
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.01.1993
• Subjects: Adult; Biological and medical sciences; Diseases of visual field, optic nerve, optic chiasma and optic tracts; Evoked Potentials, Visual - physiology; Fourier Analysis; Humans; Medical sciences; Middle Aged; Multiple Sclerosis - complications; Multiple Sclerosis - physiopathology; Ophthalmology; Optic Neuritis - physiopathology; Original Paper; Pattern Recognition, Visual; Psychophysics; Vision, Ocular - physiology; Visual Acuity; Pattern VEP; Temporal modulation transfer function; Optic neuritis; Fast Fourier transform; Human; Electrodiagnosis; Eye disease; Nervous system diseases; Temporal frequency; Optic nerve; Optic nevritis; Modulation transfer function; Exploration; Visual evoked potential pattern; Disorders of cranial nerves
• ISSN: 0030-3755; 1423-0267
• DOI: 10.1159/000310412

To reveal the impairment of the temporal modulation transfer function of vision in patients with optic neuritis, the pattern visual evoked potentials (P-VEPs) were recorded at reversal frequencies ranging from 4 to 24 per second, and the fast Fourier transform (FFT) of VEPs were investigated. In normal subjects, curves of the square root of the power of the FFTs of P-VEPs versus temporal frequency showed the maximum peak at 6 Hz (12 reversals/s). The specific distribution of the power spectrum could be found at each temporal frequency, and the amplitudes of higher harmonic components decreased while a single power spectrum peak became prominent as the temporal frequency increased. In patients with optic neuritis, an abnormality of the power spectrum of steady-state P-VEPs could by detected by estimating the 1st and 2nd harmonic components. The abnormality of the power spectrum of transient P-VEPs could be detected by estimating the higher harmonic components of the power spectrum.