Effect of silymarin pretreatment on the bioavailability of domperidone in healthy human volunteers - Yamsani, Shravan Kumar; Yamsani, Madhusudan Rao (Drug metabolism and drug interactions, 2014)
Keywords: Adult; Animals; bioavailability; Biological and medical sciences; Biological Availability; Domperidone - administration & dosage; Domperidone - blood; Drug Interactions - physiology; General pharmacology; Healthy Volunteers; Humans; intestinal transport; Male; Medical sciences; non-everted intestinal sac; Organ Culture Techniques; P-glycoprotein; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; Rats; Rats, Wistar; silymarin; Silymarin - administration & dosage; Silymarin - blood; Treatment Outcome; Domperidone; P Glycoprotein; Flavonoid; non-everted intestinal sac; Medicinal plant; Polyphenol; Drug interaction; Pretreatment; Human; silymarin; Healthy subject; Digestive system; Pharmacognosy; Dopamine antagonist; Gut; Oral administration; Bioavailability; In vitro; P-glycoprotein; In vivo; D2 Dopamine receptor; Silibinin; Phenols; intestinal transport; Pharmacokinetics; Transport; Antiemetic