BMSC-derived exosomes carrying microRNA-122-5p promote proliferation of osteoblasts in osteonecrosis of the femoral head - Liao, Wen; Ning, Yu; Xu, Hai-Jia; Zou, Wen-Zhong; Hu, Jing; Liu, Xiang-Zhong; Yang, Yi; Li, Zhang-Hua (Clinical science (1979), 2019)
Keywords: Adipogenesis - drug effects; Adipogenesis - genetics; Aniline Compounds - pharmacology; Animals; Base Sequence; Benzylidene Compounds - pharmacology; Cell Proliferation - drug effects; Disease Models, Animal; Down-Regulation - drug effects; Down-Regulation - genetics; Exosomes - drug effects; Exosomes - metabolism; Exosomes - ultrastructure; Femur Head Necrosis - diagnostic imaging; Femur Head Necrosis - pathology; Humans; Intracellular Signaling Peptides and Proteins - metabolism; Membrane Proteins - metabolism; Mesenchymal Stem Cells - drug effects; Mesenchymal Stem Cells - metabolism; MicroRNAs - genetics; MicroRNAs - metabolism; Neovascularization, Physiologic - drug effects; Neovascularization, Physiologic - genetics; Osteoblasts - drug effects; Osteoblasts - metabolism; Osteoblasts - pathology; Osteogenesis - drug effects; Osteogenesis - genetics; Rabbits; Signal Transduction; Up-Regulation - drug effects; Up-Regulation - genetics; Wound Healing - drug effects; Wound Healing - genetics; exosome; microRNA-122-5p; RTK/Ras/MAPK signaling pathway; bone marrow mesenchymal stem cell; sprouty2; osteonecrosis of the femoral head