Targeting the DNA damage response (DDR) by natural compounds - van Stuijvenberg, Jana; Proksch, Peter; Fritz, Gerhard (Bioorganic & medicinal chemistry, 2020)
Keywords: Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Biological Products - chemistry; Biological Products - pharmacology; Cell death; Cell Proliferation - drug effects; Cell Survival - drug effects; Cisplatin - pharmacology; DNA Damage; DNA damage response; DNA, Neoplasm - drug effects; Dose-Response Relationship, Drug; Doxorubicin - pharmacology; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Natural compounds; Structure-Activity Relationship; Tumor cell resistance; Tumor Cells, Cultured; H2AX; Doxo; C; FJ; DNA damage response; Natural compounds; IQ; HQ; Cis; SA; DSB; Tumor cell resistance; DDR; BV; Cell death; NC; γH2AX; cAT; ROS; ATM; VT; ATR