Unexpected effects of systemic steroids on the CRSwNP proteome: is protein upregulation more important than inhibition? - Workman, Alan D.; Miyake, Michelle M.; Nocera, Angela L.; Mueller, Sarina K.; Finn, Kristen; Otu, Hasan H.; Libermann, Towia A.; Bleier, Benjamin S. (International forum of allergy & rhinology, 2020)
Keywords: Adult; Anti-Inflammatory Agents - therapeutic use; Aptamers; Chronic Disease; chronic rhinosinusitis; CRSwNP; Exosomes - drug effects; Exosomes - metabolism; Female; Glucocorticoids - therapeutic use; Humans; Immunomodulation; Immunomodulators; Immunosuppressive agents; Male; Middle Aged; nasal polyps; Nasal Polyps - drug therapy; Nasal Polyps - metabolism; Platelet factor 4; Polyps; Prednisone; Prednisone - therapeutic use; Proteins; Proteome - drug effects; Proteome - metabolism; Proteomes; Proteomics; Rhinitis; Rhinitis - drug therapy; Rhinitis - metabolism; Rhinosinusitis; Sinusitis; Sinusitis - drug therapy; Sinusitis - metabolism; Steroid hormones; Steroids; Transcription; Up-regulation; Up-Regulation - drug effects; chronic rhinosinusitis; nasal polyps; CRSwNP; steroids; proteomics