Fibroblast growth factor‐21 protects against fibrosis in hypertensive heart disease - Ferrer‐Curriu, Gemma; Redondo‐Angulo, Ibon; Guitart‐Mampel, Mariona; Ruperez, Celia; Mas‐Stachurska, Aleksandra; Sitges, Marta; Garrabou, Gloria; Villarroya, Francesc; Fernández‐Solà, Joaquim; Planavila, Anna (The Journal of pathology, 2019)
Keywords: Angiotensin; Angiotensin II; Animal models; Animals; Biopsy; Blood pressure; Blood Pressure - physiology; Cardiomegaly - etiology; Cardiomegaly - metabolism; Cardiomegaly - pathology; Cardiomyopathy; Cardiovascular disease; Cells, Cultured; Coronary artery disease; Disease Models, Animal; FGF21; Fibroblast growth factors; Fibroblast Growth Factors - deficiency; Fibroblast Growth Factors - genetics; Fibroblast Growth Factors - metabolism; Fibroblast Growth Factors - physiology; Fibrosis; Gene Expression Regulation - physiology; Genotypes; Heart; Heart diseases; Heart Rate - physiology; Heart Ventricles - pathology; human cardiomyopathy; Humans; Hypertension; Hypertension - chemically induced; Hypertension - complications; Hypertension - metabolism; Hypertension - physiopathology; Hypertrophy; Klotho protein; Liver; Mice, Knockout; Myocardium - metabolism; Myocardium - pathology; Organ donors; Rats, Sprague-Dawley; RNA, Messenger - genetics; Rodents; Ventricle; fibrosis; human cardiomyopathy; hypertension; FGF21