Transcriptomic profiling of recessive dystrophic epidermolysis bullosa wounded skin highlights drug repurposing opportunities to improve wound healing - Onoufriadis, Alexandros; Proudfoot, Laura E.; Ainali, Chrysanthi; Torre, Denis; Papanikolaou, Maria; Rayinda, Tuntas; Rashidghamat, Ellie; Danarti, Retno; Mellerio, Jemima E.; Ma’ayan, Avi; McGrath, John A. (Experimental dermatology, 2022)
Keywords: Collagen; Collagen Type VII - genetics; Collagen Type VII - metabolism; Cytokines; Cytokines - genetics; Drug Repositioning; Dystrophic epidermolysis bullosa; Epidermolysis bullosa; Epidermolysis Bullosa Dystrophica - drug therapy; Epidermolysis Bullosa Dystrophica - genetics; expression analysis; Fibrils; Gene expression; Genes, Recessive; Humans; Methotrexate; RDEB; reverse transcriptomics; Signal transduction; Skin - metabolism; Skin diseases; Transcriptome; Transcriptomics; Wound Healing; RDEB; methotrexate; epidermolysis bullosa; expression analysis; reverse transcriptomics