Inhibition of sodium‐glucose cotransporter‐2 improves anaemia in mice and humans with sickle cell disease, and reduces infarct size in a murine stroke model - Wang, Jintao; Silaghi, Paul; Guo, Chiao; Harro, David; Eitzman, Daniel T. (Journal of cellular and molecular medicine, 2024)
Keywords: Anemia; Anemia - drug therapy; Anemia - etiology; Anemia, Sickle Cell - blood; Anemia, Sickle Cell - complications; Anemia, Sickle Cell - drug therapy; Anemia, Sickle Cell - pathology; Animal models; Animals; Benzhydryl Compounds - pharmacology; Blood tests; Blood transfusions; Bone marrow; Cardiovascular diseases; Cell size; Disease Models, Animal; Electronic health records; Electronic medical records; Erythropoietin; Female; Glucose; Glucosides - pharmacology; Hematocrit; Hemoglobin; Histology; Humans; Iron; Kidneys; Male; Mice; Mice, Inbred C57BL; Patients; Plasma; Sickle cell disease; Sodium-Glucose Transporter 2 - metabolism; Sodium-Glucose Transporter 2 Inhibitors - pharmacology; Stroke; Stroke - drug therapy; Stroke - pathology; Thrombosis; United States--US