In vitro corrosion behavior and cytotoxicity property of magnesium matrix composite with chitosan coating

Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite was prepared through powder metallurgy methods with different chitosan coatings on its surface. The properties of the chitosan coatings on the surface of Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite, such as the adhesion ability, the corrosion behavior and the cyto...

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Published inJournal of Central South University Vol. 22; no. 3; pp. 829 - 834
Main Authors Dai, Yi-long, Yu, Kun, Chen, Liang-jian, Chen, Chang, Qiao, Xue-yan, Yan, Yang
Format Journal Article
LanguageEnglish
Published Heidelberg Central South University 01.03.2015
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ISSN2095-2899
2227-5223
DOI10.1007/s11771-015-2589-4

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Abstract Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite was prepared through powder metallurgy methods with different chitosan coatings on its surface. The properties of the chitosan coatings on the surface of Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite, such as the adhesion ability, the corrosion behavior and the cytotoxicity properties, were investigated, and the microstructure of the chitosan coating was observed by scanning electron microscope (SEM). The results show that chitosan coating improves the corrosion resistance of the magnesium composite specimens significantly. Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite specimens exhibit good corrosion resistance and low pH values in simulated body fluid (SBF) at 37 °C in the immersion test with 7-layer chitosan coating whose relative molecular mass is 30×10 4 Da. The cytotoxicity tests indicate that Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 with chitosan coating is nontoxic with a cytotoxicity grade of zero against L-929 cells, which is better than that of uncoated composites.
AbstractList Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite was prepared through powder metallurgy methods with different chitosan coatings on its surface. The properties of the chitosan coatings on the surface of Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite, such as the adhesion ability, the corrosion behavior and the cytotoxicity properties, were investigated, and the microstructure of the chitosan coating was observed by scanning electron microscope (SEM). The results show that chitosan coating improves the corrosion resistance of the magnesium composite specimens significantly. Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite specimens exhibit good corrosion resistance and low pH values in simulated body fluid (SBF) at 37 °C in the immersion test with 7-layer chitosan coating whose relative molecular mass is 30×10 4 Da. The cytotoxicity tests indicate that Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 with chitosan coating is nontoxic with a cytotoxicity grade of zero against L-929 cells, which is better than that of uncoated composites.
Author Yu, Kun
Chen, Chang
Qiao, Xue-yan
Dai, Yi-long
Chen, Liang-jian
Yan, Yang
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  organization: School of Materials Science and Engineering, Central South University
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magnesium matrix composite
cytotoxicity
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Snippet Mg-6%Zn-10% β -Ca 3 (PO 4 ) 2 composite was prepared through powder metallurgy methods with different chitosan coatings on its surface. The properties of the...
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Title In vitro corrosion behavior and cytotoxicity property of magnesium matrix composite with chitosan coating
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