BRCA1 -mutated ovarian cancer with skin metastasis: a case report

The major risk factor for ovarian cancer (OC) is mutation of the or DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that - and -mutated OCs are associated with better prognosis than sporadic OCs. However, information about the pattern...

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Published inObstetrics & gynecology science Vol. 60; no. 5; pp. 477 - 480
Main Authors Oh, So Ra, Park, Jung-Woo, Kwon, Hyun Young, Rha, Seo-Hee
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Society of Obstetrics and Gynecology; Korean Society of Contraception and Reproductive Health; Korean Society of Gynecologic Endocrinology; Korean Society of Gynecologic Endoscopy and Minimal Invasive Surgery; Korean Society of Maternal Fetal Medicine; Korean Society of Ultrasound in Obstetrics and Gynecology; Korean Urogynecologic Society 01.09.2017
대한산부인과학회
Subjects
Case Report
산부인과학
Ovarian neoplasms
BRCA mutation
Skin metastases
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ISSN2287-8572
2287-8580
DOI10.5468/ogs.2017.60.5.477

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Summary:The major risk factor for ovarian cancer (OC) is mutation of the or DNA mismatch repair genes, which occurs in approximately 10% of OC cases. Most previous studies have demonstrated that - and -mutated OCs are associated with better prognosis than sporadic OCs. However, information about the patterns and clinical course of the metastatic spread of -mutated OCs is limited. Herein, we describe a case of OC with a mutation and skin metastases in a 49-year-old patient, which to the best of our knowledge has not been reported previously.
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www.ogscience.org
ISSN:2287-8572
2287-8580
DOI:10.5468/ogs.2017.60.5.477