Mechanistic study of inhibitory peptides with SHP-1 in hypertonic environment for infection model - Khandibharad, Shweta; Singh, Shailza (Biochimica et biophysica acta. General subjects, 2024)
Keywords: Animals; cutaneous leishmaniasis; Disease Models, Animal; Humans; Infection and high salt diet; infectious diseases; inflammation; interleukin-10; Interleukin-10 - metabolism; interleukin-12; Interleukin-12 - metabolism; Leishmania major; Leishmaniasis, Cutaneous - drug therapy; Leishmaniasis, Cutaneous - metabolism; Leishmaniasis, Cutaneous - parasitology; Leishmaniasis, Cutaneous - pathology; mammals; Membrane; Mice; Mice, Inbred BALB C; molecular dynamics; Molecular Dynamics Simulation; parasite load; parasites; Peptide; Peptides - chemistry; Peptides - metabolism; Peptides - pharmacology; Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism; skin lesions; sodium; therapeutics; World Health Organization; PepB; PepA; M1; M2; DBD; GLN; MCMC; RoG; H2O2; PepC; BSA; L.major; PepC-SHP1; FBS; HSD; iNOS; DMPC; Peptide; MDS; PSA; AED; PBS; BCA; Infection and high salt diet; H&E; DAPI; Molecular dynamics simulation; PLDS; NaCl; SASA; ELISA; NFAT5; NO; PepA-SHP1; GP63; FACS; SHP-1; RIPA; NPT; Membrane; ASN; intraHB; Interleukin-10; NOS2; Interleukin-12; PepB-SHP1; RMSF; TBST; TMB; CL; RMSD; HIS; PBST; TIP3P; RPMI; SH2; SH1; L.donovani