The Impact of Pharmacogenomics on Postoperative Nausea and Vomiting: Do CYP2D6 Allele Copy Number and Polymorphisms Affect the Success or Failure of Ondansetron Prophylaxis? - Candiotti, Keith A.; Birnbach, David J.; Lubarsky, David A.; Nhuch, Fani; Kamat, Aimee; Koch, Walter H.; Nikoloff, Michele; Wu, Lin; Andrews, David (Anesthesiology (Philadelphia), 2005)
Keywords: Adolescent; Adult; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Antiemetics - therapeutic use; Biological and medical sciences; Cytochrome P-450 CYP2D6 - genetics; Female; Gene Dosage; Humans; Medical sciences; Middle Aged; Ondansetron - therapeutic use; Pharmacogenetics; Polymorphism, Genetic; Postoperative Nausea and Vomiting - prevention & control; Postoperative; Prevention; Vomiting; Serotonin antagonist; 5-HT3 Serotonine receptor; Digestive diseases; Anesthesia; Nausea; Antiemetic; Ondansetron; Polymorphism