Preliminary research on dual-energy X-ray phase-contrast imaging
Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging(...
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Published in | Chinese physics C Vol. 40; no. 4; pp. 141 - 148 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
IOP Publishing
01.04.2016
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Subjects | |
Online Access | Get full text |
ISSN | 1674-1137 0254-3052 |
DOI | 10.1088/1674-1137/40/4/048201 |
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Abstract | Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging(XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials. |
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AbstractList | Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure bone mineral density (BMD) and soft-tissue composition of human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to their weak absorption. While X-ray phase-contrast imaging (XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method is aiming to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretic ones, the new method proves to have the potential to replace DEXA in area density measurement. In conclusion, the new method sets the prerequisites for future precise and low-dose area density calculation method of low-Z materials. Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging(XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials. Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure the bone mineral density (BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging (XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials. |
Author | 韩华杰 王圣浩 高昆 王志立 张灿 杨萌 张凯 朱佩平 |
AuthorAffiliation | National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230027, China School of Engineering Science, University of Science and Technology of China, Hefei 230027 China Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China |
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Notes | 11-5641/O4 DEXA refraction replace grating pixel Talbot sorption downstream precise listed Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body. However, the use of DEXA is greatly limited for lowZ materials such as soft tissues due to their weak absorption, while X-ray phase-contrast imaging(XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method aims to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretical ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for a future precise and low-dose area density calculation method for low-Z materials. Hua-Jie Han, Sheng-Hao Wang, Kun Gao, Zhi-Li Wang, Can Zhang,Meng Yang, Kai Zhang, Pei-Ping Zhu(1 National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230027, China 2 School of Engineering Science, University of Science and Technology of China, Hefei 230027, China 3 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China) ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 National Natural Science Foundation of China (NSFC) AC02-05CH11231 USDOE Office of Science (SC) |
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Snippet | Dual-energy X-ray absorptiometry(DEXA) has been widely applied to measure the bone mineral density(BMD) and soft-tissue composition of the human body.... Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure the bone mineral density (BMD) and soft-tissue composition of the human body.... Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure bone mineral density (BMD) and soft-tissue composition of human body. However, the... |
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SubjectTerms | Absorption area density Bones Density dual-energy Imaging INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY Mathematical analysis phase-contrast RADIOLOGY AND NUCLEAR MEDICINE Simulation Soft tissues X-ray imaging X-rays 双能X射线 密度测量 成像 理论计算值 相位衬度 组织成分 能量法 计算面积 |
Title | Preliminary research on dual-energy X-ray phase-contrast imaging |
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