Prediabetes and deprivation: A couple at high risk of diabetes

The higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among pre-diabetic subjects. The aim of the study was to evaluate the risk of diabetes in a population of deprived pre-diabetic patients. 2743 pre-d...

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Published inRevue d'épidémiologie et de santé publique Vol. 69; no. 6; pp. 361 - 365
Main Authors Jaffiol, C., Thomas, F., Spira, A., pannier, B., Danchin, N.
Format Journal Article
LanguageEnglish
Published Elsevier Masson SAS 01.11.2021
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ISSN0398-7620
DOI10.1016/j.respe.2021.04.139

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Abstract The higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among pre-diabetic subjects. The aim of the study was to evaluate the risk of diabetes in a population of deprived pre-diabetic patients. 2743 pre-diabetic subjects identified using the American Diabetes Association (ADA) criteria, 16 to 85 years old, 1656 non-deprived and 1087 deprived, had at least two health check-ups at an interval of 4.95 (2.04) vs 3.20 (1.71) years, P<0.0001, respectively. At the first visit, socioeconomic status was assessed using the EPICES score to differentiate deprived and non-deprived subjects. At the second visit, the prevalence of overt diabetes was 9.5% among deprived vs 5.1% in the non-deprived group (P<0.001). After adjustment on confounding factors, deprivation was found independently associated with occurrence of diabetes [1.70 (1.15–2.51), P=0.01]. Beyond social deprivation, Fasting Plasma Glucose and waist circumference were the main independent predictors of new-onset diabetes. After 4 years of follow-up, among subjects with prediabetes, prevalence of diabetes was twice as high among deprived compared with non-deprived subjects. Deprived populations with pre-diabetes may require specific public health approaches to avoid the occurrence of overt diabetes. La prévalence plus élevée du diabète chez les populations démunies est connue, mais on en sait peu sur le risque de diabète associé à la précarité chez les sujets pré-diabétiques. L’objectif de l’étude était d’évaluer le risque de diabète dans une population de patients pré-diabétiques en situation de précarité. Un total de 2743 sujets pré-diabétiques identifiés à l’aide des critères de l’American Diabetes Association (ADA) et âgés de 16 à 85 ans ont été inclus. Ils ont réalisé au moins deux bilans de santé, à un intervalle de 4,95 (2,04) ans pour les 1656 sujets non précaires et de 3,20 (1,71) ans (p<0,0001) pour les 1087 sujets précaires. Le statut socio-économique a été évalué lors de la première visite, en utilisant le score EPICES afin d’identifier les personnes en situation de précarité. À la deuxième visite, la prévalence du diabète était de 9,5 % chez les personnes en situation de précarité comparée à 5,1 % chez les personnes non précaires (p<0,001). Après ajustement sur des facteurs de confusion, la précarité était associée de façon indépendante à l’apparition du diabète [1,70 (1,15–2,51), p=0,01]. Indépendamment du niveau socio-économique, la glycémie à jeun et le tour de taille étaient les principaux prédicteurs indépendants de la survenue du diabète. Après 4 ans de suivi, chez les sujets pré-diabétiques, la prévalence du diabète était deux fois plus élevée chez les sujets en situation de précarité que chez les sujets non précaires. Les sujets défavorisés souffrant de pré-diabète nécessitent des approches de santé publique spécifiques pour éviter l’apparition de diabète.
AbstractList The higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among pre-diabetic subjects. The aim of the study was to evaluate the risk of diabetes in a population of deprived pre-diabetic patients. 2743 pre-diabetic subjects identified using the American Diabetes Association (ADA) criteria, 16 to 85 years old, 1656 non-deprived and 1087 deprived, had at least two health check-ups at an interval of 4.95 (2.04) vs 3.20 (1.71) years, P<0.0001, respectively. At the first visit, socioeconomic status was assessed using the EPICES score to differentiate deprived and non-deprived subjects. At the second visit, the prevalence of overt diabetes was 9.5% among deprived vs 5.1% in the non-deprived group (P<0.001). After adjustment on confounding factors, deprivation was found independently associated with occurrence of diabetes [1.70 (1.15–2.51), P=0.01]. Beyond social deprivation, Fasting Plasma Glucose and waist circumference were the main independent predictors of new-onset diabetes. After 4 years of follow-up, among subjects with prediabetes, prevalence of diabetes was twice as high among deprived compared with non-deprived subjects. Deprived populations with pre-diabetes may require specific public health approaches to avoid the occurrence of overt diabetes. La prévalence plus élevée du diabète chez les populations démunies est connue, mais on en sait peu sur le risque de diabète associé à la précarité chez les sujets pré-diabétiques. L’objectif de l’étude était d’évaluer le risque de diabète dans une population de patients pré-diabétiques en situation de précarité. Un total de 2743 sujets pré-diabétiques identifiés à l’aide des critères de l’American Diabetes Association (ADA) et âgés de 16 à 85 ans ont été inclus. Ils ont réalisé au moins deux bilans de santé, à un intervalle de 4,95 (2,04) ans pour les 1656 sujets non précaires et de 3,20 (1,71) ans (p<0,0001) pour les 1087 sujets précaires. Le statut socio-économique a été évalué lors de la première visite, en utilisant le score EPICES afin d’identifier les personnes en situation de précarité. À la deuxième visite, la prévalence du diabète était de 9,5 % chez les personnes en situation de précarité comparée à 5,1 % chez les personnes non précaires (p<0,001). Après ajustement sur des facteurs de confusion, la précarité était associée de façon indépendante à l’apparition du diabète [1,70 (1,15–2,51), p=0,01]. Indépendamment du niveau socio-économique, la glycémie à jeun et le tour de taille étaient les principaux prédicteurs indépendants de la survenue du diabète. Après 4 ans de suivi, chez les sujets pré-diabétiques, la prévalence du diabète était deux fois plus élevée chez les sujets en situation de précarité que chez les sujets non précaires. Les sujets défavorisés souffrant de pré-diabète nécessitent des approches de santé publique spécifiques pour éviter l’apparition de diabète.
The higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among pre-diabetic subjects. The aim of the study was to evaluate the risk of diabetes in a population of deprived pre-diabetic patients.AIMThe higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among pre-diabetic subjects. The aim of the study was to evaluate the risk of diabetes in a population of deprived pre-diabetic patients.2743 pre-diabetic subjects identified using the American Diabetes Association (ADA) criteria, 16 to 85 years old, 1656 non-deprived and 1087 deprived, had at least two health check-ups at an interval of 4.95 (2.04) vs 3.20 (1.71) years, P<0.0001, respectively. At the first visit, socioeconomic status was assessed using the EPICES score to differentiate deprived and non-deprived subjects.METHODS2743 pre-diabetic subjects identified using the American Diabetes Association (ADA) criteria, 16 to 85 years old, 1656 non-deprived and 1087 deprived, had at least two health check-ups at an interval of 4.95 (2.04) vs 3.20 (1.71) years, P<0.0001, respectively. At the first visit, socioeconomic status was assessed using the EPICES score to differentiate deprived and non-deprived subjects.At the second visit, the prevalence of overt diabetes was 9.5% among deprived vs 5.1% in the non-deprived group (P<0.001). After adjustment on confounding factors, deprivation was found independently associated with occurrence of diabetes [1.70 (1.15-2.51), P=0.01]. Beyond social deprivation, Fasting Plasma Glucose and waist circumference were the main independent predictors of new-onset diabetes.RESULTSAt the second visit, the prevalence of overt diabetes was 9.5% among deprived vs 5.1% in the non-deprived group (P<0.001). After adjustment on confounding factors, deprivation was found independently associated with occurrence of diabetes [1.70 (1.15-2.51), P=0.01]. Beyond social deprivation, Fasting Plasma Glucose and waist circumference were the main independent predictors of new-onset diabetes.After 4 years of follow-up, among subjects with prediabetes, prevalence of diabetes was twice as high among deprived compared with non-deprived subjects. Deprived populations with pre-diabetes may require specific public health approaches to avoid the occurrence of overt diabetes.CONCLUSIONAfter 4 years of follow-up, among subjects with prediabetes, prevalence of diabetes was twice as high among deprived compared with non-deprived subjects. Deprived populations with pre-diabetes may require specific public health approaches to avoid the occurrence of overt diabetes.
Author pannier, B.
Spira, A.
Danchin, N.
Jaffiol, C.
Thomas, F.
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Keywords Type 2 diabetes
Pré-diabète
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Deprivation
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Prediabetes
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Snippet The higher prevalence of diabetes in deprived populations is well documented but little is known about the risk of diabetes associated with deprivation among...
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SubjectTerms Deprivation
Diabète de type 2
Prediabetes
Pré-diabète
Précarité
Type 2 diabetes
Title Prediabetes and deprivation: A couple at high risk of diabetes
URI https://dx.doi.org/10.1016/j.respe.2021.04.139
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