Rapid detection of thiabendazole in food using SERS coupled with flower-like AgNPs and PSL-based variable selection algorithms

Thiabendazole (TBZ) exposure through food can have substantial long-term health consequences for humans. Herein, SERS coupled with flower-like AgNPs and python-scikit-learn (PSL) algorithms, was proposed for rapid detection of TBZ. Initially, AgNFs with a strong enhancement factor (EF) of 1.303 × 10...

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Published inJournal of food composition and analysis Vol. 115; p. 105016
Main Authors Li, Huanhuan, Luo, Xiaofeng, Haruna, Suleiman A., Zhou, Wenjie, Chen, Quansheng
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.01.2023
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ISSN0889-1575
1096-0481
DOI10.1016/j.jfca.2022.105016

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Abstract Thiabendazole (TBZ) exposure through food can have substantial long-term health consequences for humans. Herein, SERS coupled with flower-like AgNPs and python-scikit-learn (PSL) algorithms, was proposed for rapid detection of TBZ. Initially, AgNFs with a strong enhancement factor (EF) of 1.303 × 106 were synthesized to collect TBZ spectra. Subsequently, three PSL-based variable selection algorithms, including SelectKBest (SKB), variance threshold (VT) and recursive feature elimination (RFE), were comparatively applied to select the informative variables for TBZ prediction. The RFE exhibited the optimal selection ability, and RFE-SVM achieved the best performance for TBZ prediction (Rp2 = 0.976, RPD = 6.477), with a computed limit of detection (LOD) of 0.24 μg/mL obtained. Finally, good recoveries of spiked samples (78.5–95.09%) were obtained, demonstrating that the proposed method is practicable and potentially effective for TBZ rapidly detection in food. •AgNFs-based SERS coupled with PSL algorithms for TBZ has proposed.•AgNFs with a strong enhancement factor of 1.303 × 106 were synthesized.•SKB, VT, RFE variable selection methods were comparatively investigated.•RFE-SVM achieved the most accurate prediction of TBZ with RPD of 6.477.•The proposed robust SERS-RFE-SVM method for TBZ obtained a LOD of 0.24 μg/mL.
AbstractList Thiabendazole (TBZ) exposure through food can have substantial long-term health consequences for humans. Herein, SERS coupled with flower-like AgNPs and python-scikit-learn (PSL) algorithms, was proposed for rapid detection of TBZ. Initially, AgNFs with a strong enhancement factor (EF) of 1.303 × 10⁶ were synthesized to collect TBZ spectra. Subsequently, three PSL-based variable selection algorithms, including SelectKBest (SKB), variance threshold (VT) and recursive feature elimination (RFE), were comparatively applied to select the informative variables for TBZ prediction. The RFE exhibited the optimal selection ability, and RFE-SVM achieved the best performance for TBZ prediction (Rp² = 0.976, RPD = 6.477), with a computed limit of detection (LOD) of 0.24 μg/mL obtained. Finally, good recoveries of spiked samples (78.5–95.09%) were obtained, demonstrating that the proposed method is practicable and potentially effective for TBZ rapidly detection in food.
Thiabendazole (TBZ) exposure through food can have substantial long-term health consequences for humans. Herein, SERS coupled with flower-like AgNPs and python-scikit-learn (PSL) algorithms, was proposed for rapid detection of TBZ. Initially, AgNFs with a strong enhancement factor (EF) of 1.303 × 106 were synthesized to collect TBZ spectra. Subsequently, three PSL-based variable selection algorithms, including SelectKBest (SKB), variance threshold (VT) and recursive feature elimination (RFE), were comparatively applied to select the informative variables for TBZ prediction. The RFE exhibited the optimal selection ability, and RFE-SVM achieved the best performance for TBZ prediction (Rp2 = 0.976, RPD = 6.477), with a computed limit of detection (LOD) of 0.24 μg/mL obtained. Finally, good recoveries of spiked samples (78.5–95.09%) were obtained, demonstrating that the proposed method is practicable and potentially effective for TBZ rapidly detection in food. •AgNFs-based SERS coupled with PSL algorithms for TBZ has proposed.•AgNFs with a strong enhancement factor of 1.303 × 106 were synthesized.•SKB, VT, RFE variable selection methods were comparatively investigated.•RFE-SVM achieved the most accurate prediction of TBZ with RPD of 6.477.•The proposed robust SERS-RFE-SVM method for TBZ obtained a LOD of 0.24 μg/mL.
ArticleNumber 105016
Author Zhou, Wenjie
Luo, Xiaofeng
Haruna, Suleiman A.
Chen, Quansheng
Li, Huanhuan
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Python-scikit-learn
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Snippet Thiabendazole (TBZ) exposure through food can have substantial long-term health consequences for humans. Herein, SERS coupled with flower-like AgNPs and...
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SubjectTerms detection limit
Flower-like AgNPs
food composition
prediction
Python-scikit-learn
rapid methods
RFE-SVM
Thiabendazole
variance
Title Rapid detection of thiabendazole in food using SERS coupled with flower-like AgNPs and PSL-based variable selection algorithms
URI https://dx.doi.org/10.1016/j.jfca.2022.105016
https://www.proquest.com/docview/3153854765
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