Effects of postnatal administration of ethanol on the M. gastrocnemius of the albino mouse

A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the albino mouse. The experimental group received ethanol in the drinking water until sacrifice at the age of 40 days. Based on the fiber composi...

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Published inDrug and alcohol dependence Vol. 23; no. 2; pp. 137 - 142
Main Authors González-Hernández, T.H., Molina-Rodríguez, A., Llabrés-Olmo, J., González-Reimers, C.E., Pérez-González, H., Meyer, G.
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.04.1989
Elsevier Science
Subjects
Alcoholism and acute alcohol poisoning
Animals
Biological and medical sciences
Body Weight - drug effects
ethanol
Ethanol - pharmacology
histochemistry
Histocytochemistry
mATPase
Medical sciences
Mice
Mice, Nude
morphometry
muscle
Muscle Development
Muscles - drug effects
Muscles - pathology
Myosins - analysis
Organ Size - drug effects
Toxicology
morphometry
mATPase
histochemistry
ethanol
muscle
Ethanol
Toxicity
ATPase
Rodentia
Postnatal development
Vertebrata
Mammalia
Mouse
Animal
Myosin
Muscle
Gastrocnemius muscle
Morphometry
Histochemistry
Myopathy
Online AccessGet full text
ISSN0376-8716
1879-0046
DOI10.1016/0376-8716(89)90019-7

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Abstract A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the albino mouse. The experimental group received ethanol in the drinking water until sacrifice at the age of 40 days. Based on the fiber composition, three different areas are distinguished in the m. gastrocnemius of the mouse. The typical location of these areas does not change after ethanol administration. However, postnatal administration of ethanol produces a selective atrophy and a decrease of the number of type IIb (fast glycolytic) fibers. Concurrently, the number of type IIa (fast oxidative-glycolytic) fibers increases.
AbstractList A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the albino mouse. The experimental group received ethanol in the drinking water until sacrifice at the age of 40 days. Based on the fiber composition, three different areas are distinguished in the m. gastrocnemius of the mouse. The typical location of these areas does not change after ethanol administration. However, postnatal administration of ethanol produces a selective atrophy and a decrease of the number of type IIb (fast glycolytic) fibers. Concurrently, the number of type IIa (fast oxidative-glycolytic) fibers increases.
A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the albino mouse. The experimental group received ethanol in the drinking water until sacrifice at the age of 40 days. Based on the fiber composition, three different areas are distinguished in the m. gastrocnemius of the mouse. The typical location of these areas does not change after ethanol administration. However, postnatal administration of ethanol produces a selective atrophy and a decrease of the number of type IIb (fast glycolytic) fibers. Concurrently, the number of type IIa (fast oxidative-glycolytic) fibers increases.
A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the albino mouse. The experimental group received ethanol in the drinking water until sacrifice at the age of 40 days. Based on the fiber composition, three different areas are distinguished in the m. gastrocnemius of the mouse. The typical location of these areas does not change after ethanol administration. However, postnatal administration of ethanol produces a selective atrophy and a decrease of the number of type IIb (fast glycolytic) fibers. Concurrently, the number of type IIa (fast oxidative-glycolytic) fibers increases.A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the albino mouse. The experimental group received ethanol in the drinking water until sacrifice at the age of 40 days. Based on the fiber composition, three different areas are distinguished in the m. gastrocnemius of the mouse. The typical location of these areas does not change after ethanol administration. However, postnatal administration of ethanol produces a selective atrophy and a decrease of the number of type IIb (fast glycolytic) fibers. Concurrently, the number of type IIa (fast oxidative-glycolytic) fibers increases.
Author González-Hernández, T.H.
Meyer, G.
González-Reimers, C.E.
Molina-Rodríguez, A.
Llabrés-Olmo, J.
Pérez-González, H.
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Issue 2
Keywords morphometry
mATPase
histochemistry
ethanol
muscle
Ethanol
Toxicity
ATPase
Rodentia
Postnatal development
Vertebrata
Mammalia
Mouse
Animal
Myosin
Muscle
Gastrocnemius muscle
Morphometry
Histochemistry
Myopathy
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Snippet A combined morphometric-histochemical (mATPase) study of the effects of ethanol during postnatal development on the m. gastrocnemius has been performed in the...
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StartPage 137
SubjectTerms Alcoholism and acute alcohol poisoning
Animals
Biological and medical sciences
Body Weight - drug effects
ethanol
Ethanol - pharmacology
histochemistry
Histocytochemistry
mATPase
Medical sciences
Mice
Mice, Nude
morphometry
muscle
Muscle Development
Muscles - drug effects
Muscles - pathology
Myosins - analysis
Organ Size - drug effects
Toxicology
Title Effects of postnatal administration of ethanol on the M. gastrocnemius of the albino mouse
URI https://dx.doi.org/10.1016/0376-8716(89)90019-7
https://www.ncbi.nlm.nih.gov/pubmed/2522873
https://www.proquest.com/docview/15254025
https://www.proquest.com/docview/78886745
Volume 23
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