Panax ginseng ginsenoside-Rg₂ protects memory impairment via anti-apoptosis in a rat model with vascular dementia - Zhang, Guizhi; Liu, Ailing; Zhou, Yingbin; San, Xun; Jin, Taowei; Jin, Yi (Journal of ethnopharmacology, 2008)
Keywords: animal models; Animals; apoptosis; Apoptosis - drug effects; bcl-2-Associated X Protein - drug effects; bcl-2-Associated X Protein - metabolism; Biological and medical sciences; brain; central nervous system diseases; dementia; Dementia, Vascular - drug therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation - drug effects; General pharmacology; ginsenoside; Ginsenosides - administration & dosage; Ginsenosides - isolation & purification; Ginsenosides - pharmacology; heat shock proteins; herbal medicines; HSP70 Heat-Shock Proteins - drug effects; HSP70 Heat-Shock Proteins - metabolism; ischemia; Male; Medical sciences; medicinal plants; medicinal properties; memory; Memory Disorders - drug therapy; nervous system; Nimodipine - pharmacology; Panax - chemistry; Panax ginseng; Pharmacognosy. Homeopathy. Health food; Pharmacology. Drug treatments; protein synthesis; Proto-Oncogene Proteins c-bcl-2 - drug effects; Proto-Oncogene Proteins c-bcl-2 - metabolism; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 - drug effects; Tumor Suppressor Protein p53 - metabolism; Vasodilator Agents - pharmacology; Asia; China; Steroid; Neuroprotection; Rat; Memory; Cardiovascular disease; Panax ginseng; Medicinal plant; Saponin; Prevention; Folk medicine; Dicotyledones; Angiospermae; Degenerative disease; Glycoside; Araliaceae; Cerebrovascular disease; Terpenoid; Nervous system diseases; Vascular dementia; Pharmacognosy; Rodentia; Cerebral disorder; Vertebrata; Mammalia; Cell death; Animal; Central nervous system disease; Plant origin; Triterpene; Spermatophyta; Apoptosis