Structure-Based Virtual Screening of Protein Tyrosine Phosphatase Inhibitors: Significance, Challenges, and Solutions - R, Harikrishna Reddy; Kim, Hackyoung; Cha, Seungbin; Lee, Bongsoo; Kim, Young Jun (Journal of microbiology and biotechnology, 2017)
Keywords: Catalytic Domain; Diabetes Mellitus - drug therapy; Disease; Drug Delivery Systems; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Humans; Models, Molecular; Molecular Docking Simulation; Neoplasms - drug therapy; Phosphoric Monoester Hydrolases - physiology; Phosphorylation - physiology; Phosphotransferases - physiology; Protein Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1 - drug effects; Protein Tyrosine Phosphatase, Non-Receptor Type 1 - physiology; Protein Tyrosine Phosphatases - chemistry; Protein Tyrosine Phosphatases - classification; Protein Tyrosine Phosphatases - drug effects; Protein Tyrosine Phosphatases - physiology; 생물학; Allosteric targeting; cancers; molecular docking; drug designing; diabetes; protein tyrosine phosphatases