Adaptive-mesh-based algorithm for fluorescence molecular tomography using an analytical solution
Fluorescence molecular tomography (FMT) has become an important method for in-vivo imaging of small animals. It has been widely used for tumor genesis, cancer detection, metastasis, drug discovery, and gene therapy. In this study, an algorithm for FMT is proposed to obtain accurate and fast reconstr...
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| Published in | Optics express Vol. 15; no. 15; p. 9722 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
23.07.2007
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| Online Access | Get full text |
| ISSN | 1094-4087 1094-4087 |
| DOI | 10.1364/OE.15.009722 |
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| Summary: | Fluorescence molecular tomography (FMT) has become an important method for in-vivo imaging of small animals. It has been widely used for tumor genesis, cancer detection, metastasis, drug discovery, and gene therapy. In this study, an algorithm for FMT is proposed to obtain accurate and fast reconstruction by combining an adaptive mesh refinement technique and an analytical solution of diffusion equation. Numerical studies have been performed on a parallel plate FMT system with matching fluid. The reconstructions obtained show that the algorithm is efficient in computation time, and they also maintain image quality. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1094-4087 1094-4087 |
| DOI: | 10.1364/OE.15.009722 |