Age‐dependent accumulation of monoclonal CD4+CD8+double positive T lymphocytes in the peripheral blood of the elderly - Ghia, Paolo; Prato, Giuseppina; Stella, Stefania; Scielzo, Cristina; Geuna, Massimo; Caligaris‐Cappio, Federico (British journal of haematology, 2007)
Keywords: Adult; Aged; Aged, 80 and over; Aging - immunology; Biological and medical sciences; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; chronic lymphocytic leukaemia; Female; Flow Cytometry - methods; Genes, T-Cell Receptor beta; Hematologic and hematopoietic diseases; Humans; immune senescence; Immunoglobulin Variable Region - genetics; Immunophenotyping; large granular lymphocytic leukaemia; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Lymphocytosis - immunology; lymphoproliferative disorder; Male; Medical sciences; Middle Aged; Polymerase Chain Reaction - methods; Receptors, Antigen, T-Cell, alpha-beta - genetics; T-Lymphocyte Subsets - immunology; T‐cell receptor gene; Human; T cell receptor; Hematology; T-cell receptor gene; Malignant hemopathy; Blood; large granular lymphocytic leukaemia; Chronic lymphocytic leukemia; lymphoproliferative disorder; chronic lymphocytic leukaemia; Gene; Lymphoproliferative syndrome; T-Lymphocyte; Genetics; Immunosenescence; Elderly; Age; Cancer; immune senescence