Pharmacokinetic comparison of a fixed-dose combination of telmisartan/rosuvastatin/ezetimibe/amlodipine 80/20/10/5 mg and a loose-dose combination of ezetimibe/rosuvastatin 10/20 mg and telmisartan/amlodipine 80/5 mg in healthy male subjects - Lee, Sooyoun; Kim, Hyun Chul; Kim, Kyung Tae; Kang, Seung-Hyun; Lee, SeungHwan; Yu, Kyung-Sang; Lee, Soyoung (Naunyn-Schmiedeberg's archives of pharmacology, 2025)
Keywords: Adult; Amlodipine - administration & dosage; Amlodipine - adverse effects; Amlodipine - blood; Amlodipine - pharmacokinetics; Anticholesteremic Agents - administration & dosage; Anticholesteremic Agents - pharmacokinetics; Area Under Curve; Benzimidazoles - administration & dosage; Benzimidazoles - adverse effects; Benzimidazoles - blood; Benzimidazoles - pharmacokinetics; Benzoates - administration & dosage; Benzoates - pharmacokinetics; Biomedical and Life Sciences; Biomedicine; Blood pressure; Cholesterol; Clinical medicine; Cross-Over Studies; Dosage; Drug Combinations; Drug dosages; Electrocardiography; Ezetimibe - administration & dosage; Ezetimibe - adverse effects; Ezetimibe - blood; Ezetimibe - pharmacokinetics; Healthy Volunteers; Humans; Hypertension; Male; Medical laboratories; Metabolic disorders; Neurosciences; Patient compliance; Pharmacokinetics; Pharmacology/Toxicology; Rosuvastatin Calcium - administration & dosage; Rosuvastatin Calcium - adverse effects; Rosuvastatin Calcium - blood; Rosuvastatin Calcium - pharmacokinetics; Statins; Telmisartan - administration & dosage; Telmisartan - pharmacokinetics; Young Adult; United States--US; South Korea; Hypertension; Bioequivalence; Pharmacokinetics; Fixed-dose combination; Dyslipidemia