Aortic aneurysms
The prevalence of aortic aneurysm is increasing; it is responsible for 1–2% of all deaths in men aged over 65 years in the Western world. The majority of aortic aneurysms affect the abdominal portion of the aorta. The disease most commonly represents a multifactorial degenerative process involving b...
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Published in | Surgery (Oxford) Vol. 27; no. 8; pp. 342 - 345 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Elsevier Ltd
2009
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Subjects | |
Online Access | Get full text |
ISSN | 0263-9319 1878-1764 |
DOI | 10.1016/j.mpsur.2009.06.003 |
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Abstract | The prevalence of aortic aneurysm is increasing; it is responsible for 1–2% of all deaths in men aged over 65 years in the Western world. The majority of aortic aneurysms affect the abdominal portion of the aorta. The disease most commonly represents a multifactorial degenerative process involving both genetic and environmental risk factors. It is characterized pathologically by a reduction in elastic lamellae within the aortic wall. The natural history of the condition is one of progressive enlargement with an associated increase risk of aneurysm rupture. Although aneurysm rupture remains a catastrophic event, with an overall mortality of approximately 80%, the majority of patients are asymptomatic. Asymptomatic aneurysms are usually diagnosed as an incidental finding and management relies on an assessment of the risks of future aneurysm rupture weighed against the risks associated with elective surgical repair. Aneurysm repair may be accomplished by traditional open surgery or minimally invasive endovascular repair. Although the latter confers a short- and medium-term survival advantage in selected patients, long-term follow-up data are still awaited. |
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AbstractList | The prevalence of aortic aneurysm is increasing; it is responsible for 1–2% of all deaths in men aged over 65 years in the Western world. The majority of aortic aneurysms affect the abdominal portion of the aorta. The disease most commonly represents a multifactorial degenerative process involving both genetic and environmental risk factors. It is characterized pathologically by a reduction in elastic lamellae within the aortic wall. The natural history of the condition is one of progressive enlargement with an associated increase risk of aneurysm rupture. Although aneurysm rupture remains a catastrophic event, with an overall mortality of approximately 80%, the majority of patients are asymptomatic. Asymptomatic aneurysms are usually diagnosed as an incidental finding and management relies on an assessment of the risks of future aneurysm rupture weighed against the risks associated with elective surgical repair. Aneurysm repair may be accomplished by traditional open surgery or minimally invasive endovascular repair. Although the latter confers a short- and medium-term survival advantage in selected patients, long-term follow-up data are still awaited. Abstract The prevalence of aortic aneurysm is increasing; it is responsible for 1–2% of all deaths in men aged over 65 years in the Western world. The majority of aortic aneurysms affect the abdominal portion of the aorta. The disease most commonly represents a multifactorial degenerative process involving both genetic and environmental risk factors. It is characterized pathologically by a reduction in elastic lamellae within the aortic wall. The natural history of the condition is one of progressive enlargement with an associated increase risk of aneurysm rupture. Although aneurysm rupture remains a catastrophic event, with an overall mortality of approximately 80%, the majority of patients are asymptomatic. Asymptomatic aneurysms are usually diagnosed as an incidental finding and management relies on an assessment of the risks of future aneurysm rupture weighed against the risks associated with elective surgical repair. Aneurysm repair may be accomplished by traditional open surgery or minimally invasive endovascular repair. Although the latter confers a short- and medium-term survival advantage in selected patients, long-term follow-up data are still awaited. |
Author | Chalmers, Roderick T.A. Tambyraja, Andrew L. |
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Cites_doi | 10.1056/NEJMct0707524 10.1016/S0140-6736(02)11522-4 10.1016/S0140-6736(98)10137-X |
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Keywords | thoracoabdominal aneurysm screening aortic rupture |
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References | Greenhalgh (10.1016/j.mpsur.2009.06.003_fr1) 2008; 358 (10.1016/j.mpsur.2009.06.003_fr3) 1998; 352 (10.1016/j.mpsur.2009.06.003_fr2) 2002; 360 |
References_xml | – volume: 358 start-page: 494 year: 2008 ident: 10.1016/j.mpsur.2009.06.003_fr1 article-title: Endovascular repair of abdominal aortic aneurysm publication-title: N Engl J Med doi: 10.1056/NEJMct0707524 – volume: 360 start-page: 1531 year: 2002 ident: 10.1016/j.mpsur.2009.06.003_fr2 article-title: Multicentre Aneurysm Screening Study Group. The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a randomised controlled trial publication-title: Lancet doi: 10.1016/S0140-6736(02)11522-4 – volume: 352 start-page: 1649 year: 1998 ident: 10.1016/j.mpsur.2009.06.003_fr3 article-title: The UK Small Aneurysm Trial Participants. Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms publication-title: Lancet doi: 10.1016/S0140-6736(98)10137-X |
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Snippet | The prevalence of aortic aneurysm is increasing; it is responsible for 1–2% of all deaths in men aged over 65 years in the Western world. The majority of... Abstract The prevalence of aortic aneurysm is increasing; it is responsible for 1–2% of all deaths in men aged over 65 years in the Western world. The majority... |
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StartPage | 342 |
SubjectTerms | aneurysm aortic rupture screening Surgery thoracoabdominal |
Title | Aortic aneurysms |
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