Conjunctive p16INK4a Testing Significantly Increases Accuracy in Diagnosing High-Grade Cervical Intraepithelial Neoplasia - Bergeron, Christine; Ordi, Jaume; Schmidt, Dietmar; Trunk, Marcus J.; Keller, Thomas; Ridder, Ruediger (American journal of clinical pathology, 2010)
Keywords: Adult; Analysis of Variance; Biological and medical sciences; Cervical Intraepithelial Neoplasia - diagnosis; Cervical Intraepithelial Neoplasia - metabolism; Cyclin-Dependent Kinase Inhibitor p16 - metabolism; Female; Female genital diseases; Gynecology. Andrology. Obstetrics; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Observer Variation; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Predictive Value of Tests; Reference Standards; Reproducibility of Results; Tumors; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - metabolism; Immunohistochemistry; Premalignant lesion; Cervical biopsy; Increase; Medical screening; CDKN2 gene; Female genital diseases; High grade; Interrater reliability; Anatomic pathology; Accuracy; Cervical dysplasia; p16; Biopsy; Cervical intraepithelial neoplasia; Diagnostic accuracy; Interindividual comparison; Diagnosis; Reliability; Uterine cervix diseases; Tumor suppressor gene; High malignancy