Nutritional potassium limitation impact on serum potassium change, and death in chronic kidney disease: A meta‐analysis

Introduction We performed a meta‐analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease. Methods A systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidne...

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Published inTherapeutic apheresis and dialysis Vol. 26; no. 6; pp. 1079 - 1085
Main Authors Gong, Zhumei, Chen, Taiai
Format Journal Article
LanguageEnglish
Published Kyoto, Japan John Wiley & Sons Australia, Ltd 01.12.2022
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ISSN1744-9979
1744-9987
1744-9987
DOI10.1111/1744-9987.13831

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Abstract Introduction We performed a meta‐analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease. Methods A systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidney disease at the start of the study; 41 474 of them were provided with nutritional potassium limitation and 510 084 were nonrestricted diet. Results Nutritional potassium limitation had significantly lower serum potassium change (MD, −0.33; 95% CI, −0.58 to −0.07; p = 0.01) compared to nonrestricted diet in subjects with chronic kidney disease. However, nutritional potassium limitation had no significant impact on the death (OR, 0.80; 95% CI, 0.58–1.10; p = 0.17) compared to nonrestricted diet in subjects with chronic kidney disease. Conclusion Nutritional potassium limitation had significantly lower serum potassium change compared to nonrestricted diet in subjects with chronic kidney disease. Further studies are required to validate these findings.
AbstractList Introduction We performed a meta‐analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease. Methods A systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidney disease at the start of the study; 41 474 of them were provided with nutritional potassium limitation and 510 084 were nonrestricted diet. Results Nutritional potassium limitation had significantly lower serum potassium change (MD, −0.33; 95% CI, −0.58 to −0.07; p = 0.01) compared to nonrestricted diet in subjects with chronic kidney disease. However, nutritional potassium limitation had no significant impact on the death (OR, 0.80; 95% CI, 0.58–1.10; p = 0.17) compared to nonrestricted diet in subjects with chronic kidney disease. Conclusion Nutritional potassium limitation had significantly lower serum potassium change compared to nonrestricted diet in subjects with chronic kidney disease. Further studies are required to validate these findings.
We performed a meta-analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease.INTRODUCTIONWe performed a meta-analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease.A systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidney disease at the start of the study; 41 474 of them were provided with nutritional potassium limitation and 510 084 were nonrestricted diet.METHODSA systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidney disease at the start of the study; 41 474 of them were provided with nutritional potassium limitation and 510 084 were nonrestricted diet.Nutritional potassium limitation had significantly lower serum potassium change (MD, -0.33; 95% CI, -0.58 to -0.07; p = 0.01) compared to nonrestricted diet in subjects with chronic kidney disease. However, nutritional potassium limitation had no significant impact on the death (OR, 0.80; 95% CI, 0.58-1.10; p = 0.17) compared to nonrestricted diet in subjects with chronic kidney disease.RESULTSNutritional potassium limitation had significantly lower serum potassium change (MD, -0.33; 95% CI, -0.58 to -0.07; p = 0.01) compared to nonrestricted diet in subjects with chronic kidney disease. However, nutritional potassium limitation had no significant impact on the death (OR, 0.80; 95% CI, 0.58-1.10; p = 0.17) compared to nonrestricted diet in subjects with chronic kidney disease.Nutritional potassium limitation had significantly lower serum potassium change compared to nonrestricted diet in subjects with chronic kidney disease. Further studies are required to validate these findings.CONCLUSIONNutritional potassium limitation had significantly lower serum potassium change compared to nonrestricted diet in subjects with chronic kidney disease. Further studies are required to validate these findings.
We performed a meta-analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease. A systematic literature search up to October 2021 was carried out and eight studies included 92 558 subjects with chronic kidney disease at the start of the study; 41 474 of them were provided with nutritional potassium limitation and 510 084 were nonrestricted diet. Nutritional potassium limitation had significantly lower serum potassium change (MD, -0.33; 95% CI, -0.58 to -0.07; p = 0.01) compared to nonrestricted diet in subjects with chronic kidney disease. However, nutritional potassium limitation had no significant impact on the death (OR, 0.80; 95% CI, 0.58-1.10; p = 0.17) compared to nonrestricted diet in subjects with chronic kidney disease. Nutritional potassium limitation had significantly lower serum potassium change compared to nonrestricted diet in subjects with chronic kidney disease. Further studies are required to validate these findings.
Author Gong, Zhumei
Chen, Taiai
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Keywords mortality
chronic kidney disease
nonrestricted diet
nutritional potassium limitation in chronic kidney disease
serum potassium change
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Snippet Introduction We performed a meta‐analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney...
We performed a meta-analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney disease. A...
We performed a meta-analysis to evaluate the impact of nutritional potassium limitation on serum potassium change, and death in chronic kidney...
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SubjectTerms chronic kidney disease
mortality
nonrestricted diet
nutritional potassium limitation in chronic kidney disease
serum potassium change
Title Nutritional potassium limitation impact on serum potassium change, and death in chronic kidney disease: A meta‐analysis
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2F1744-9987.13831
https://www.ncbi.nlm.nih.gov/pubmed/35247229
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