The technology for improving stability of nanosuspensions in drug delivery

  This review was devoted to the technology and approach for improving nanosuspensions stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of the present review included the nanosuspensions’ preparation approach, methods and guidelines for selection and opti...

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Published inJournal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology Vol. 24; no. 1
Main Authors Guan, Wenhao, Ma, Yingying, Ding, Shuaijie, Liu, Yanchao, Song, Zimin, Liu, Xiang, Tang, Lingling, Wang, Yancai
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Netherlands 01.01.2022
Springer Nature B.V
Subjects
Bioavailability
Candidates
Characterization and Evaluation of Materials
Chemistry and Materials Science
Drug delivery
Drug delivery systems
Drugs
Inorganic Chemistry
Lasers
Materials Science
Nanocrystals
Nanoparticles
Nanotechnology
Optical Devices
Optics
Particle size
Pensions
Pharmaceutical industry
Photonics
Physical Chemistry
Review
Solidification
Solids
Spray drying
Stability
Nanosuspensions
Freeze-drying
Solidification
Online AccessGet full text
ISSN1388-0764
1572-896X
DOI10.1007/s11051-022-05403-9

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Abstract   This review was devoted to the technology and approach for improving nanosuspensions stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of the present review included the nanosuspensions’ preparation approach, methods and guidelines for selection and optimizing stabilizers, the approaches for enhancing stability, and the other influencing factors on the stability of the prepared nanosuspensions. For a given drug candidate having a set of properties, this review could be invoked as a reference in making an educated choice of stabilizer and improving the nanosuspensions’ stability, rather than a trial-and-error approach that is being practiced currently.
AbstractList Abstract This review was devoted to the technology and approach for improving nanosuspensions stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of the present review included the nanosuspensions’ preparation approach, methods and guidelines for selection and optimizing stabilizers, the approaches for enhancing stability, and the other influencing factors on the stability of the prepared nanosuspensions. For a given drug candidate having a set of properties, this review could be invoked as a reference in making an educated choice of stabilizer and improving the nanosuspensions’ stability, rather than a trial-and-error approach that is being practiced currently.
  This review was devoted to the technology and approach for improving nanosuspensions stability in drug delivery to retrieve the state-of-the-art nanosuspensions. The main content of the present review included the nanosuspensions’ preparation approach, methods and guidelines for selection and optimizing stabilizers, the approaches for enhancing stability, and the other influencing factors on the stability of the prepared nanosuspensions. For a given drug candidate having a set of properties, this review could be invoked as a reference in making an educated choice of stabilizer and improving the nanosuspensions’ stability, rather than a trial-and-error approach that is being practiced currently.
ArticleNumber 14
Author Liu, Xiang
Ding, Shuaijie
Ma, Yingying
Tang, Lingling
Song, Zimin
Guan, Wenhao
Liu, Yanchao
Wang, Yancai
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  orcidid: 0000-0002-9465-2610
  surname: Wang
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  email: wangyancai1999@163.com
  organization: School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences)
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IEDL.DBID U2A
ISSN 1388-0764
IngestDate Fri Jul 25 12:21:35 EDT 2025
Tue Jul 01 04:31:41 EDT 2025
Thu Apr 24 23:12:51 EDT 2025
Fri Feb 21 02:47:26 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Spray drying
Stability
Nanosuspensions
Freeze-drying
Solidification
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c319t-a9e9627af6823735842e548a271c3018959cb5e13ab5ef5e4d30df6a40c7fdcc3
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content type line 14
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PQID 2618749748
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crossref_primary_10_1007_s11051_022_05403_9
crossref_citationtrail_10_1007_s11051_022_05403_9
springer_journals_10_1007_s11051_022_05403_9
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PublicationDate 20220100
2022-01-00
20220101
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  year: 2022
  text: 20220100
PublicationDecade 2020
PublicationPlace Dordrecht
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PublicationSubtitle An Interdisciplinary Forum for Nanoscale Science and Technology
PublicationTitle Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology
PublicationTitleAbbrev J Nanopart Res
PublicationYear 2022
Publisher Springer Netherlands
Springer Nature B.V
Publisher_xml – name: Springer Netherlands
– name: Springer Nature B.V
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Abstract This review was devoted to the technology and approach for improving nanosuspensions stability in drug delivery to retrieve the state-of-the-art...
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SubjectTerms Bioavailability
Candidates
Characterization and Evaluation of Materials
Chemistry and Materials Science
Drug delivery
Drug delivery systems
Drugs
Inorganic Chemistry
Lasers
Materials Science
Nanocrystals
Nanoparticles
Nanotechnology
Optical Devices
Optics
Particle size
Pensions
Pharmaceutical industry
Photonics
Physical Chemistry
Review
Solidification
Solids
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Title The technology for improving stability of nanosuspensions in drug delivery
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