Hybridization of soft-computing algorithms with neural network for prediction obstructive sleep apnea using biomedical sensor measurements

• Published in: Neural computing & applications Vol. 34; no. 11; pp. 8933 - 8957
• Main Authors: Chyad, Mustafa Habeeb, Gharghan, Sadik Kamel, Hamood, Haider Qasim, Altayyar, Ahmed Saleh Hameed, Zubaidi, Salah L., Ridha, Hussein Mohammed
• Format: Journal Article
• Language: English
• Published: London Springer London 01.06.2022; Springer Nature B.V
• Subjects: Algorithms; Artificial Intelligence; Artificial neural networks; Computational Biology/Bioinformatics; Computational Science and Engineering; Computer Science; Data Mining and Knowledge Discovery; Heart rate; Image Processing and Computer Vision; Learning theory; Motion sensors; Muscles; Neural networks; Original Article; Probability and Statistics in Computer Science; Respiratory diseases; Sleep apnea; Soft computing; Heart rate; Sleep apnea; SpO; Artificial neural network; Soft computing algorithm; Prediction
• ISSN: 0941-0643; 1433-3058
• DOI: 10.1007/s00521-022-06919-w

Sleep apnea (SA) is a common respiratory disorder, especially among obese people. It is caused by either the relaxation of the upper respiratory tract muscles or the failure of the neural signal to reach the muscles responsible for breathing, both of which interrupt the patient’s sleep–wake cycles. The traditional method for diagnosing this disorder, based on polysomnography, is complicated, vexing, expensive, time-consuming, and requires both sleep centers and specialized staff capable of connecting electrodes to the patient’s body. This paper proposes an SA prediction system based on merging five soft computing algorithms, specifically, combining the multi-verse optimizer (MVO) with an artificial neural network (ANN) to leverage measurements from heart rate, SpO 2 , and chest movement sensors. The most substantial novelty of this research is the hybridization of MVO and ANN (MVO-ANN), which improves the ANN performance by selecting the best learning rate and number of neurons in hidden ANN layers. This enables highly accurate prediction of sleep apnea events. This work’s experimental results reveal that the MVO-ANN performs better than other algorithms, with mean absolute errors of 0.042, 0.202, and 0.166 for training, testing, and validation of the ANN. In addition, the SA prediction system achieved an accuracy of 98.67%, a sensitivity of 96.71%, and a specificity of 99.24%. These results provide good evidence that the proposed method can reliably predict respiratory events in people suffering from SA.