The impact of sex in the effectiveness of functional remediation in bipolar disorder

Background Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long‐term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a valid...

Full description

Saved in:

Bibliographic Details
Published in	Acta psychiatrica Scandinavica Vol. 150; no. 6; pp. 543 - 561
Main Authors	Serra‐Navarro, Maria, Clougher, Derek, Solé, Brisa, Sánchez‐Moreno, Jose, González‐Pinto, Ana, Jiménez, Esther, Amann, Benedikt L., Balanzá‐Martínez, Vicent, Tabarés‐Seisdedos, Rafael, Arango, Celso, Accardo, Vivian, García‐Portilla, María Paz, Ibáñez, Ángela, Crespo, José Manuel, Ayuso‐Mateos, José Luis, Amoretti, Silvia, Torrent, Carla, Martínez‐Aran, Anabel, Vieta, Eduard, Forte, Maria Florencia, Montejo, Laura, Mar Bonnín, Caterina, Ortiz‐Gil, Jordi, Segura, Barbara, Landín‐Romero, Ramon, Alonso‐Lana, Silvia, Saiz‐Ruiz, Jerónimo, León‐Quismondo, Leticia, Ochoa‐Mangado, Enriqueta, Bertolin, Sara, Custal, Nuria, Menchon, Jose Manuel, Azua, Sonia Ruiz, Mar‐Barrutia, Lorea, Haidar, Karim, Correa‐Ghisays, Patricia, Selva‐Vera, Gabriel, Fuentes‐Durá, Inmaculada, Ferrer‐Quintero, Marta, Echevarria‐Bruno, Ana, Díaz‐Caneja, Covadonga M.
Format	Journal Article
Language	English
Published	United States Blackwell Publishing Ltd 01.12.2024
Subjects	Bipolar disorder Cognition Females functional remediation Gender differences Males psychosocial functioning Recovery of function Sex differences Social interactions Sociodemographics bipolar disorder psychosocial functioning functional remediation sex differences
Online Access	Get full text
ISSN	0001-690X 1600-0447 1600-0447
DOI	10.1111/acps.13748

Cover

Abstract	Background Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long‐term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD. The present study assessed the effect of sex differences of FR on psychosocial functioning at post‐treatment (6‐months) and 12‐month follow‐up (FUP). To the best of our knowledge, this is the first study to explore the role of sex as a factor in the efficacy of FR. Methods 157 participants with BD were randomly assigned to either FR (N = 77) or treatment as usual group (80). Clinical, sociodemographic, neuropsychological, and functional data were obtained using a comprehensive assessment battery. Sex differences were explored via a general linear model (GLM) for repeated measures to compare the effect of sex on the intervention over time (6 months and FUP). Results Results demonstrated that FR benefits both sexes, males (p = 0.001; d’ = 0.88) and females (p = 0.04; d’ = 0.57), at 6 months suggesting a generalized functional improvement. Conversely, at 12‐month FUP sex differences were observed only in males (p = 0.005; d’ = 0.68). Conclusions FR is a beneficial intervention for males and females after treatment, suggesting that there are no relevant distinct needs. Females may benefit from ongoing psychosocial functioning booster sessions after the intervention to maintain original improvements. Future research exploring sex differences could help to identify strategies to offer personalized FR intervention approaches in individuals with BD.
AbstractList	Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long-term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD. The present study assessed the effect of sex differences of FR on psychosocial functioning at post-treatment (6-months) and 12-month follow-up (FUP). To the best of our knowledge, this is the first study to explore the role of sex as a factor in the efficacy of FR. 157 participants with BD were randomly assigned to either FR (N = 77) or treatment as usual group (80). Clinical, sociodemographic, neuropsychological, and functional data were obtained using a comprehensive assessment battery. Sex differences were explored via a general linear model (GLM) for repeated measures to compare the effect of sex on the intervention over time (6 months and FUP). Results demonstrated that FR benefits both sexes, males (p = 0.001; d' = 0.88) and females (p = 0.04; d' = 0.57), at 6 months suggesting a generalized functional improvement. Conversely, at 12-month FUP sex differences were observed only in males (p = 0.005; d' = 0.68). FR is a beneficial intervention for males and females after treatment, suggesting that there are no relevant distinct needs. Females may benefit from ongoing psychosocial functioning booster sessions after the intervention to maintain original improvements. Future research exploring sex differences could help to identify strategies to offer personalized FR intervention approaches in individuals with BD. BackgroundFunctional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long‐term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD. The present study assessed the effect of sex differences of FR on psychosocial functioning at post‐treatment (6‐months) and 12‐month follow‐up (FUP). To the best of our knowledge, this is the first study to explore the role of sex as a factor in the efficacy of FR.Methods157 participants with BD were randomly assigned to either FR (N = 77) or treatment as usual group (80). Clinical, sociodemographic, neuropsychological, and functional data were obtained using a comprehensive assessment battery. Sex differences were explored via a general linear model (GLM) for repeated measures to compare the effect of sex on the intervention over time (6 months and FUP).ResultsResults demonstrated that FR benefits both sexes, males (p = 0.001; d’ = 0.88) and females (p = 0.04; d’ = 0.57), at 6 months suggesting a generalized functional improvement. Conversely, at 12‐month FUP sex differences were observed only in males (p = 0.005; d’ = 0.68).ConclusionsFR is a beneficial intervention for males and females after treatment, suggesting that there are no relevant distinct needs. Females may benefit from ongoing psychosocial functioning booster sessions after the intervention to maintain original improvements. Future research exploring sex differences could help to identify strategies to offer personalized FR intervention approaches in individuals with BD. Background Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long‐term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD. The present study assessed the effect of sex differences of FR on psychosocial functioning at post‐treatment (6‐months) and 12‐month follow‐up (FUP). To the best of our knowledge, this is the first study to explore the role of sex as a factor in the efficacy of FR. Methods 157 participants with BD were randomly assigned to either FR (N = 77) or treatment as usual group (80). Clinical, sociodemographic, neuropsychological, and functional data were obtained using a comprehensive assessment battery. Sex differences were explored via a general linear model (GLM) for repeated measures to compare the effect of sex on the intervention over time (6 months and FUP). Results Results demonstrated that FR benefits both sexes, males (p = 0.001; d’ = 0.88) and females (p = 0.04; d’ = 0.57), at 6 months suggesting a generalized functional improvement. Conversely, at 12‐month FUP sex differences were observed only in males (p = 0.005; d’ = 0.68). Conclusions FR is a beneficial intervention for males and females after treatment, suggesting that there are no relevant distinct needs. Females may benefit from ongoing psychosocial functioning booster sessions after the intervention to maintain original improvements. Future research exploring sex differences could help to identify strategies to offer personalized FR intervention approaches in individuals with BD. Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long-term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD. The present study assessed the effect of sex differences of FR on psychosocial functioning at post-treatment (6-months) and 12-month follow-up (FUP). To the best of our knowledge, this is the first study to explore the role of sex as a factor in the efficacy of FR.BACKGROUNDFunctional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are associated with long-term functional impairment, yet the impact of sex differences is unclear. Functional remediation (FR) is a validated intervention aimed at achieving functional recovery in BD. The present study assessed the effect of sex differences of FR on psychosocial functioning at post-treatment (6-months) and 12-month follow-up (FUP). To the best of our knowledge, this is the first study to explore the role of sex as a factor in the efficacy of FR.157 participants with BD were randomly assigned to either FR (N = 77) or treatment as usual group (80). Clinical, sociodemographic, neuropsychological, and functional data were obtained using a comprehensive assessment battery. Sex differences were explored via a general linear model (GLM) for repeated measures to compare the effect of sex on the intervention over time (6 months and FUP).METHODS157 participants with BD were randomly assigned to either FR (N = 77) or treatment as usual group (80). Clinical, sociodemographic, neuropsychological, and functional data were obtained using a comprehensive assessment battery. Sex differences were explored via a general linear model (GLM) for repeated measures to compare the effect of sex on the intervention over time (6 months and FUP).Results demonstrated that FR benefits both sexes, males (p = 0.001; d' = 0.88) and females (p = 0.04; d' = 0.57), at 6 months suggesting a generalized functional improvement. Conversely, at 12-month FUP sex differences were observed only in males (p = 0.005; d' = 0.68).RESULTSResults demonstrated that FR benefits both sexes, males (p = 0.001; d' = 0.88) and females (p = 0.04; d' = 0.57), at 6 months suggesting a generalized functional improvement. Conversely, at 12-month FUP sex differences were observed only in males (p = 0.005; d' = 0.68).FR is a beneficial intervention for males and females after treatment, suggesting that there are no relevant distinct needs. Females may benefit from ongoing psychosocial functioning booster sessions after the intervention to maintain original improvements. Future research exploring sex differences could help to identify strategies to offer personalized FR intervention approaches in individuals with BD.CONCLUSIONSFR is a beneficial intervention for males and females after treatment, suggesting that there are no relevant distinct needs. Females may benefit from ongoing psychosocial functioning booster sessions after the intervention to maintain original improvements. Future research exploring sex differences could help to identify strategies to offer personalized FR intervention approaches in individuals with BD.
Author	Ochoa‐Mangado, Enriqueta Ayuso‐Mateos, José Luis González‐Pinto, Ana Amann, Benedikt L. Ortiz‐Gil, Jordi Segura, Barbara Landín‐Romero, Ramon Alonso‐Lana, Silvia Menchon, Jose Manuel Ibáñez, Ángela Díaz‐Caneja, Covadonga M. Vieta, Eduard Azua, Sonia Ruiz Correa‐Ghisays, Patricia Jiménez, Esther Martínez‐Aran, Anabel García‐Portilla, María Paz Accardo, Vivian Crespo, José Manuel Arango, Celso Bertolin, Sara Selva‐Vera, Gabriel Balanzá‐Martínez, Vicent Serra‐Navarro, Maria Solé, Brisa Custal, Nuria Sánchez‐Moreno, Jose Mar Bonnín, Caterina Montejo, Laura Ferrer‐Quintero, Marta Haidar, Karim Fuentes‐Durá, Inmaculada León‐Quismondo, Leticia Echevarria‐Bruno, Ana Torrent, Carla Mar‐Barrutia, Lorea Forte, Maria Florencia Tabarés‐Seisdedos, Rafael Saiz‐Ruiz, Jerónimo Clougher, Derek Amoretti, Silvia
Author_xml	– sequence: 1 givenname: Maria surname: Serra‐Navarro fullname: Serra‐Navarro, Maria organization: Health Institute Carlos III (ISCIII) – sequence: 2 givenname: Derek orcidid: 0000-0001-7631-3845 surname: Clougher fullname: Clougher, Derek organization: University of the Basque Country – sequence: 3 givenname: Brisa surname: Solé fullname: Solé, Brisa organization: Health Institute Carlos III (ISCIII) – sequence: 4 givenname: Jose surname: Sánchez‐Moreno fullname: Sánchez‐Moreno, Jose organization: Health Institute Carlos III (ISCIII) – sequence: 5 givenname: Ana surname: González‐Pinto fullname: González‐Pinto, Ana organization: University of the Basque Country – sequence: 6 givenname: Esther surname: Jiménez fullname: Jiménez, Esther organization: University of the Basque Country – sequence: 7 givenname: Benedikt L. orcidid: 0000-0002-4407-1519 surname: Amann fullname: Amann, Benedikt L. organization: Pompeu Fabra University – sequence: 8 givenname: Vicent orcidid: 0000-0001-7772-7396 surname: Balanzá‐Martínez fullname: Balanzá‐Martínez, Vicent organization: University of Valencia, INCLIVA – sequence: 9 givenname: Rafael orcidid: 0000-0002-1089-2204 surname: Tabarés‐Seisdedos fullname: Tabarés‐Seisdedos, Rafael organization: University of Valencia, INCLIVA – sequence: 10 givenname: Celso surname: Arango fullname: Arango, Celso organization: IiSGM, School of Medicine – sequence: 11 givenname: Vivian surname: Accardo fullname: Accardo, Vivian organization: ASST Spedali Civili of Brescia – sequence: 12 givenname: María Paz orcidid: 0000-0003-3643-1622 surname: García‐Portilla fullname: García‐Portilla, María Paz organization: University of Oviedo – sequence: 13 givenname: Ángela surname: Ibáñez fullname: Ibáñez, Ángela organization: Universidad de Alcalá – sequence: 14 givenname: José Manuel surname: Crespo fullname: Crespo, José Manuel organization: University Hospital of Bellvitge – sequence: 15 givenname: José Luis surname: Ayuso‐Mateos fullname: Ayuso‐Mateos, José Luis organization: Universidad Autónoma de Madrid – sequence: 16 givenname: Silvia surname: Amoretti fullname: Amoretti, Silvia email: silvia.amoretti@vhir.org organization: Vall d'Hebron Research Institute (VHIR) – sequence: 17 givenname: Carla surname: Torrent fullname: Torrent, Carla email: ctorrent@recerca.clinic.cat organization: Health Institute Carlos III (ISCIII) – sequence: 18 givenname: Anabel surname: Martínez‐Aran fullname: Martínez‐Aran, Anabel organization: Health Institute Carlos III (ISCIII) – sequence: 19 givenname: Eduard orcidid: 0000-0002-0548-0053 surname: Vieta fullname: Vieta, Eduard organization: Health Institute Carlos III (ISCIII) – sequence: 21 givenname: Maria Florencia surname: Forte fullname: Forte, Maria Florencia – sequence: 22 givenname: Laura surname: Montejo fullname: Montejo, Laura – sequence: 23 givenname: Caterina surname: Mar Bonnín fullname: Mar Bonnín, Caterina – sequence: 24 givenname: Jordi surname: Ortiz‐Gil fullname: Ortiz‐Gil, Jordi – sequence: 25 givenname: Barbara surname: Segura fullname: Segura, Barbara – sequence: 26 givenname: Ramon surname: Landín‐Romero fullname: Landín‐Romero, Ramon – sequence: 27 givenname: Silvia surname: Alonso‐Lana fullname: Alonso‐Lana, Silvia – sequence: 28 givenname: Jerónimo surname: Saiz‐Ruiz fullname: Saiz‐Ruiz, Jerónimo – sequence: 29 givenname: Leticia surname: León‐Quismondo fullname: León‐Quismondo, Leticia – sequence: 30 givenname: Enriqueta surname: Ochoa‐Mangado fullname: Ochoa‐Mangado, Enriqueta – sequence: 31 givenname: Sara surname: Bertolin fullname: Bertolin, Sara – sequence: 32 givenname: Nuria surname: Custal fullname: Custal, Nuria – sequence: 33 givenname: Jose Manuel surname: Menchon fullname: Menchon, Jose Manuel – sequence: 34 givenname: Sonia Ruiz surname: Azua fullname: Azua, Sonia Ruiz – sequence: 35 givenname: Lorea surname: Mar‐Barrutia fullname: Mar‐Barrutia, Lorea – sequence: 36 givenname: Karim surname: Haidar fullname: Haidar, Karim – sequence: 37 givenname: Patricia surname: Correa‐Ghisays fullname: Correa‐Ghisays, Patricia – sequence: 38 givenname: Gabriel surname: Selva‐Vera fullname: Selva‐Vera, Gabriel – sequence: 39 givenname: Inmaculada surname: Fuentes‐Durá fullname: Fuentes‐Durá, Inmaculada – sequence: 40 givenname: Marta surname: Ferrer‐Quintero fullname: Ferrer‐Quintero, Marta – sequence: 41 givenname: Ana surname: Echevarria‐Bruno fullname: Echevarria‐Bruno, Ana – sequence: 42 givenname: Covadonga M. surname: Díaz‐Caneja fullname: Díaz‐Caneja, Covadonga M.
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/39243167$$D View this record in MEDLINE/PubMed
BookMark	eNp90U1LwzAYB_AgE_eiFz-AFLyI0JmnydL2OIZvMFBwgreStk8wo2tqsqr79qZ2evBgLuGf_JLw5BmTQW1qJOQU6BT8uJJF46bAYp4ckBEISkPKeTwgI0ophCKlL0Mydm7t4wxockSGLI04AxGPyGr1ioHeNLLYBkYFDj8DXQdbv4hKYbHV71ijc92eamufTS2rwOIGSy271PFcN6aSNii1M7ZEe0wOlawcnuznCXm-uV4t7sLlw-39Yr4MC_94EpZMyFxITFXMqeAJSgCRsjyFNFUsTiJWCoaqwDzhUMR0hhjzsuRcAKCKGJuQi_7expq3Ft0222hXYFXJGk3rMgYU4pSLKPH0_A9dm9b6WjoVsVkyY1R4dbZXbe4rzBqrN9Lusp__8uCyB4U1zllUvwRo1jUj65qRfTfDY-jxh65w94_M5ovHp_7MF3KtilA
Cites_doi	10.1111/j.1600‐0447.2010.01590.x 10.2466/pms.1958.8.3.271 10.1037/h0054651 10.1016/j.euroneuro.2023.06.006 10.1155/2014/418432 10.1016/j.jad.2017.12.038 10.1016/j.jad.2014.02.034 10.1037/a0029299 10.1136/jnnp.23.1.56 10.1186/1745‐0179‐3‐5 10.3233/WOR‐2012‐1402 10.1016/j.jad.2008.10.023 10.1016/j.jad.2013.10.044 10.1002/wps.20351 10.1016/j.jad.2021.08.125 10.1016/j.euroneuro.2023.03.001 10.1016/j.jad.2011.04.055 10.1080/165019701750098902 10.1176/appi.ajp.2007.05081484 10.3109/00048670903446882 10.1176/appi.ajp.2012.12070971 10.1097/NMD.0000000000001224 10.1192/bjp.bp.114.162123 10.3109/09540261.2010.514601 10.1016/j.jad.2021.09.066 10.1037/a0022677 10.2217/whe.11.71 10.1017/S1355617721001442 10.3389/fpsyt.2018.00641 10.1016/j.euroneuro.2010.08.001 10.1017/CBO9781107415867 10.1111/acps.12894 10.1016/j.jad.2014.11.058 10.1016/j.jad.2009.05.014 10.2174/1745017901107010112 10.2147/NDT.S207544 10.1017/S0033291715001713 10.1017/S0033291709991644 10.1192/bjp.133.5.429 10.1016/j.euroneuro.2019.04.002 10.1080/10503307.2015.1072285 10.1016/j.euroneuro.2021.10.771
ContentType	Journal Article
Contributor	León-Quismondo, Leticia Ferrer-Quintero, Marta Bertolin, Sara Alonso-Lana, Silvia Del Mar Bonnín, Caterina Segura, Barbara Ortiz-Gil, Jordi Custal, Nuria Correa-Ghisays, Patricia Menchon, Jose Manuel de Azua, Sonia Ruiz Saiz-Ruiz, Jerónimo Mar-Barrutia, Lorea Díaz-Caneja, Covadonga M Montejo, Laura Echevarria-Bruno, Ana Landín-Romero, Ramon Haidar, Karim Fuentes-Durá, Inmaculada Selva-Vera, Gabriel Ochoa-Mangado, Enriqueta Forte, Maria Florencia
Contributor_xml	– sequence: 1 givenname: Maria Florencia surname: Forte fullname: Forte, Maria Florencia – sequence: 2 givenname: Laura surname: Montejo fullname: Montejo, Laura – sequence: 3 givenname: Caterina surname: Del Mar Bonnín fullname: Del Mar Bonnín, Caterina – sequence: 4 givenname: Jordi surname: Ortiz-Gil fullname: Ortiz-Gil, Jordi – sequence: 5 givenname: Barbara surname: Segura fullname: Segura, Barbara – sequence: 6 givenname: Ramon surname: Landín-Romero fullname: Landín-Romero, Ramon – sequence: 7 givenname: Silvia surname: Alonso-Lana fullname: Alonso-Lana, Silvia – sequence: 8 givenname: Jerónimo surname: Saiz-Ruiz fullname: Saiz-Ruiz, Jerónimo – sequence: 9 givenname: Leticia surname: León-Quismondo fullname: León-Quismondo, Leticia – sequence: 10 givenname: Enriqueta surname: Ochoa-Mangado fullname: Ochoa-Mangado, Enriqueta – sequence: 11 givenname: Sara surname: Bertolin fullname: Bertolin, Sara – sequence: 12 givenname: Nuria surname: Custal fullname: Custal, Nuria – sequence: 13 givenname: Jose Manuel surname: Menchon fullname: Menchon, Jose Manuel – sequence: 14 givenname: Sonia Ruiz surname: de Azua fullname: de Azua, Sonia Ruiz – sequence: 15 givenname: Lorea surname: Mar-Barrutia fullname: Mar-Barrutia, Lorea – sequence: 16 givenname: Karim surname: Haidar fullname: Haidar, Karim – sequence: 17 givenname: Patricia surname: Correa-Ghisays fullname: Correa-Ghisays, Patricia – sequence: 18 givenname: Gabriel surname: Selva-Vera fullname: Selva-Vera, Gabriel – sequence: 19 givenname: Inmaculada surname: Fuentes-Durá fullname: Fuentes-Durá, Inmaculada – sequence: 20 givenname: Marta surname: Ferrer-Quintero fullname: Ferrer-Quintero, Marta – sequence: 21 givenname: Ana surname: Echevarria-Bruno fullname: Echevarria-Bruno, Ana – sequence: 22 givenname: Covadonga M surname: Díaz-Caneja fullname: Díaz-Caneja, Covadonga M
Copyright	2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Copyright_xml	– notice: 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
CorporateAuthor	CIBERSAM Functional Remediation Group
CorporateAuthor_xml	– name: CIBERSAM Functional Remediation Group
DBID	AAYXX CITATION NPM 7TK K9. 7X8
DOI	10.1111/acps.13748
DatabaseName	CrossRef PubMed Neurosciences Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic
DatabaseTitle	CrossRef PubMed ProQuest Health & Medical Complete (Alumni) Neurosciences Abstracts MEDLINE - Academic
DatabaseTitleList	PubMed ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine
EISSN	1600-0447
EndPage	561
ExternalDocumentID	39243167 10_1111_acps_13748 ACPS13748
Genre	researchArticle Journal Article
GrantInformation_xml	– fundername: Sara Borrell Doctoral Program funderid: CD20/00177 – fundername: Departament de Salut de la Generalitat de Catalunya for the Pla estratègic de recerca I innovació en salut funderid: SLT006/17/00177 – fundername: ISCIII‐Subdirección General de Evaluación and the Fondo Europeo de Desarrollo Regional (FEDER) – fundername: Spanish Ministry of Science and Innovation – fundername: European Union (FEDER) – fundername: European Social Fund – fundername: Project PRISM‐2 funderid: 101034377 – fundername: CIBERSAM, Madrid Regional Government funderid: B2017/BMD‐3740 AGES‐CM‐2 – fundername: “Miguel Servet” postdoctoral contract funderid: CPI14/00175 – fundername: Spanish Ministry of Innovation and Science – fundername: CIBERSAM, the Basque Government grantid: 2022111054 – fundername: Spanish Ministry of Economy and Competitiveness grantid: PI080180 – fundername: Departament de Salut de la Generalitat de Catalunya for the Pla estratègic de recerca I innovació en salut grantid: SLT006/17/00177 – fundername: European Union-NextGenerationEU grantid: PI19/01024 – fundername: Spanish Ministry of Economy and Competitiveness grantid: PI08/90654 – fundername: Spanish Ministry of Economy and Competitiveness grantid: PI08/90327 – fundername: Sara Borrell Doctoral Program grantid: CD20/00177 – fundername: Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación; by the Madrid Regional Government grantid: S2022/BMD-7216 – fundername: Spanish Ministry of Economy and Competitiveness grantid: PI12/00912
GroupedDBID	--- -~X .3N .55 .GA .GJ .Y3 05W 0R~ 10A 1OB 1OC 23M 31~ 33P 36B 3O- 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAESR AAEVG AAHHS AAHQN AAIPD AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABDBF ABEML ABIVO ABJNI ABLJU ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACFBH ACGFS ACGOF ACHQT ACMXC ACPOU ACPRK ACRPL ACSCC ACUHS ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN ADZOD AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFEBI AFFNX AFFPM AFGKR AFPWT AFWVQ AFZJQ AHBTC AHEFC AHMBA AIACR AITYG AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMXJE BROTX BRXPI BY8 C45 CAG COF CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DUUFO EAD EAP EAS EBC EBD EBS EJD EMB EMK EMOBN EPS ESX EX3 F00 F01 F04 F5P FEDTE FUBAC FZ0 G-S GODZA H.X HF~ HGLYW HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO L7B LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OHT OIG OVD P2P P2W P2X P2Z P4B P4D PALCI PQQKQ Q.N Q11 QB0 R.K RIWAO RJQFR ROL RX1 SAMSI SUPJJ SV3 TEORI TUS UB1 UPT V9Y W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQJ WRC WUP WVDHM WXI WXSBR X7M XG1 YF5 ZGI ZXP ZZTAW ~IA ~WT AAYXX AEYWJ AGHNM AGQPQ AGYGG CITATION AAMMB AEFGJ AGXDD AIDQK AIDYY NPM 7TK K9. 7X8
ID	FETCH-LOGICAL-c3168-d36ab6ae9f740648ea11693b9199f37823d63efceb841c705ee74dd44611ef233
IEDL.DBID	DR2
ISSN	0001-690X 1600-0447
IngestDate	Fri Sep 05 09:05:15 EDT 2025 Sat Jul 26 00:34:58 EDT 2025 Fri Jul 04 01:52:38 EDT 2025 Tue Jul 01 04:08:36 EDT 2025 Wed Jan 22 17:15:25 EST 2025
IsPeerReviewed	true
IsScholarly	true
Issue	6
Keywords	bipolar disorder psychosocial functioning functional remediation sex differences
Language	English
License	2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c3168-d36ab6ae9f740648ea11693b9199f37823d63efceb841c705ee74dd44611ef233
Notes	Anabel Martínez‐Aran and Eduard Vieta should be considered joint last author. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ORCID	0000-0001-7772-7396 0000-0001-7631-3845 0000-0003-3643-1622 0000-0002-0548-0053 0000-0002-1089-2204 0000-0002-4407-1519
PMID	39243167
PQID	3123585306
PQPubID	33508
PageCount	19
ParticipantIDs	proquest_miscellaneous_3101794628 proquest_journals_3123585306 pubmed_primary_39243167 crossref_primary_10_1111_acps_13748 wiley_primary_10_1111_acps_13748_ACPS13748
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	December 2024 2024-12-00 2024-Dec 20241201
PublicationDateYYYYMMDD	2024-12-01
PublicationDate_xml	– month: 12 year: 2024 text: December 2024
PublicationDecade	2020
PublicationPlace	United States
PublicationPlace_xml	– name: United States – name: Aalborg
PublicationTitle	Acta psychiatrica Scandinavica
PublicationTitleAlternate	Acta Psychiatr Scand
PublicationYear	2024
Publisher	Blackwell Publishing Ltd
Publisher_xml	– name: Blackwell Publishing Ltd
References	2023; 75 2022; 296 2013; 44 2016; 208 2018; 229 2017; 27 1986; 14 2019; 15 2010; 121 1976 2008 2010; 122 1997 1978; 133 2014; 2014 2004 2014; 155 2016; 15 2020; 208 1935; 18 2011; 133 2011; 7 2010; 40 2009; 116 2010; 22 1993. 2015; 174 2010; 44 2018; 9 2018; 138 2023; 29 2000 1960; 23 1987 1958; 8 2019; 29 2011; 21 2021; 295 2014 2011; 25 2007; 3 2014; 160 2022; 55 2013; 170 2001; 33 2023; 71 2016; 46 Conners CK (e_1_2_11_36_1) 2004 e_1_2_11_51_1 e_1_2_11_13_1 e_1_2_11_11_1 e_1_2_11_6_1 e_1_2_11_4_1 Ramos‐Brieva JA (e_1_2_11_27_1) 1986; 14 e_1_2_11_48_1 e_1_2_11_2_1 American Psychiatric Association (e_1_2_11_24_1) 2000 e_1_2_11_20_1 e_1_2_11_45_1 e_1_2_11_47_1 e_1_2_11_41_1 e_1_2_11_8_1 e_1_2_11_22_1 e_1_2_11_43_1 e_1_2_11_17_1 e_1_2_11_15_1 Weschler D (e_1_2_11_29_1) 1997 e_1_2_11_38_1 e_1_2_11_19_1 e_1_2_11_50_1 e_1_2_11_10_1 e_1_2_11_31_1 e_1_2_11_14_1 e_1_2_11_52_1 e_1_2_11_12_1 e_1_2_11_33_1 e_1_2_11_7_1 e_1_2_11_5_1 e_1_2_11_26_1 e_1_2_11_3_1 e_1_2_11_49_1 Heaton R (e_1_2_11_30_1) 1993 Rey A (e_1_2_11_34_1) 1997 e_1_2_11_21_1 e_1_2_11_44_1 e_1_2_11_46_1 e_1_2_11_25_1 e_1_2_11_40_1 e_1_2_11_9_1 e_1_2_11_23_1 e_1_2_11_42_1 e_1_2_11_18_1 Delis DC (e_1_2_11_35_1) 1987 Benton A (e_1_2_11_32_1) 1976 e_1_2_11_16_1 e_1_2_11_37_1 e_1_2_11_39_1 Guy W (e_1_2_11_28_1) 1976
References_xml	– volume: 116 start-page: 37 issue: 1–2 year: 2009 end-page: 42 article-title: Neurocognitive and symptomatic predictors of functional outcome in bipolar disorders: a prospective 1 year follow‐up study publication-title: J Affect Disord – volume: 155 start-page: 162 issue: 1 year: 2014 end-page: 168 article-title: Sex differences in cognitive functioning in patients with bipolar disorder who recently recovered from a first episode of mania: data from the systematic treatment optimization program for early mania (STOP‐EM) publication-title: J Affect Disord – volume: 8 start-page: 271 issue: 3 year: 1958 end-page: 276 article-title: Validity of the trail making test as an indicator of organic brain damage publication-title: Percept Mot Skills – volume: 133 start-page: 443 issue: 3 year: 2011 end-page: 449 article-title: Gender differences in a cohort study of 604 bipolar patients: the role of predominant polarity publication-title: J Affect Disord – volume: 7 start-page: 663 issue: 6 year: 2011 end-page: 676 article-title: Bipolar disorder differences between genders: special considerations for women publication-title: Womens Health – volume: 3 start-page: 5 year: 2007 article-title: Validity and reliability of the functioning assessment short test (FAST) in bipolar disorder publication-title: Clin Pract Epidemiol Ment Health – volume: 23 start-page: 56 issue: 1 year: 1960 end-page: 62 article-title: A rating scale for depression publication-title: J Neurol Neurosurg Psychiatry – year: 2014 – volume: 29 start-page: 701 issue: 6 year: 2019 end-page: 710 article-title: Functional remediation improves bipolar disorder functioning with no effects on brain‐derived neurotrophic factor levels publication-title: Eur Neuropsychopharmacol – volume: 2014 start-page: 1 year: 2014 end-page: 10 article-title: Sex dependence of cognitive functions in bipolar disorder publication-title: Sci World J – volume: 15 start-page: 288 year: 2016 end-page: 289 article-title: Functional remediation: the pathway from remission to recovery in bipolar disorder publication-title: World Psychiatry – volume: 27 start-page: 74 year: 2017 end-page: 88 article-title: Effects of sex and gender in ten types of psychotherapy publication-title: Psychother Res – volume: 170 start-page: 852 issue: 8 year: 2013 end-page: 859 article-title: Efficacy of functional remediation in bipolar disorder: a multicenter randomized controlled study publication-title: Am J Psychiatry – volume: 40 start-page: 1349 year: 2010 end-page: 1355 article-title: Gender differences in immediate memory in bipolar disorder publication-title: Psychol Med – year: 2008 – year: 2004 – volume: 160 start-page: 50 year: 2014 end-page: 54 article-title: Verbal memory as a mediator in the relationship between subthreshold depressive symptoms and functional outcome in bipolar disorder publication-title: J Affect Disord – volume: 22 start-page: 437 issue: 5 year: 2010 end-page: 452 article-title: Is sex important gender differences in bipolar disorder publication-title: Int Rev Psychiatry – year: 1997 – volume: 121 start-page: 156 issue: 1–2 year: 2010 end-page: 160 article-title: Clinical and neurocognitive predictors of functional outcome in bipolar euthymic patients: a long‐term, follow‐up study publication-title: J Affect Disord – volume: 208 start-page: 87 issue: 1 year: 2016 end-page: 93 article-title: Functional remediation in bipolar disorder: 1‐year follow‐up of neurocognitive and functional outcome publication-title: Br J Psychiatry – volume: 7 start-page: 112 issue: 1 year: 2011 end-page: 116 article-title: Functional remediation for bipolar disorder publication-title: Clin Pract Epidemiol Ment Health – year: 1976 – year: 1993. – volume: 33 start-page: 71 issue: 2 year: 2001 end-page: 78 article-title: Factors associated with successful vocational rehabilitation in a Swedish rural area publication-title: J Rehabil Med – volume: 44 start-page: 449 issue: 4 year: 2013 end-page: 457 article-title: Employability and work ability: returning to the labour market after long‐term absence publication-title: Work – volume: 75 start-page: 41 year: 2023 end-page: 58 – volume: 174 start-page: 303 year: 2015 end-page: 309 article-title: Gender differences in the treatment of patients with bipolar disorder: a study of 7354 patients publication-title: J Affect Disord – volume: 21 start-page: 287 issue: 4 year: 2011 end-page: 293 article-title: 2‐year course of bipolar disorder type I patients in outpatient care: factors associated with remission and functional recovery publication-title: Eur Neuropsychopharmacol – volume: 208 start-page: 904 issue: 11 year: 2020 end-page: 907 article-title: Predictors of high psychosocial functioning in bipolar disorder publication-title: J Nerv Ment Dis – volume: 29 start-page: 12 issue: 1 year: 2023 end-page: 23 article-title: Characterisation of deficits and sex differences in verbal and visual memory/learning in bipolar disorder publication-title: J Int Neuropsychol Soc – year: 1987 – year: 2000 – volume: 229 start-page: 95 year: 2018 end-page: 104 article-title: Gender differences in C‐reactive protein and homocysteine modulation of cognitive performance and real‐world functioning in bipolar disorder publication-title: J Affect Disord – volume: 295 start-page: 431 year: 2021 end-page: 437 article-title: Sex differences in cognitive function of first‐diagnosed and drug‐naïve patients with bipolar disorder publication-title: J Affect Disord – volume: 18 start-page: 643 issue: 6 year: 1935 end-page: 662 article-title: Studies of interference in serial verbal reactions publication-title: J Exp Psychol – volume: 44 start-page: 29 issue: 1 year: 2013 end-page: 36 article-title: Sex differences in college students' preferences for an ideal psychotherapist publication-title: Prof Psychol Res Pract – volume: 25 start-page: 499 issue: 4 year: 2011 end-page: 510 article-title: Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder publication-title: Neuropsychology – volume: 46 start-page: 291 issue: 2 year: 2016 end-page: 301 article-title: Effects of functional remediation on neurocognitively impaired bipolar patients: enhancement of verbal memory publication-title: Psychol Med – volume: 14 start-page: 335 issue: 4 year: 1986 end-page: 338 article-title: Relation between the validity and reliability of the Castillian version of the Hamilton rating scale for depression publication-title: Actas Luso Esp Neurol Psiquiatr Cienc Afines – volume: 138 start-page: 145 issue: 2 year: 2018 end-page: 154 article-title: Factors associated with poor functional outcome in bipolar disorder: sociodemographic, clinical, and neurocognitive variables publication-title: Acta Psychiatr Scand – volume: 133 start-page: 429 year: 1978 end-page: 435 article-title: A rating scale for mania publication-title: Br J Psychiatry – volume: 44 start-page: 220 issue: 3 year: 2010 end-page: 229 article-title: Use of the repeatable battery for the assessment of neuropsychological status (RBANS) to investigate group and gender differences in schizophrenia and bipolar disorder publication-title: Aust N Z J Psychiatry – volume: 71 start-page: 6 year: 2023 end-page: 8 – volume: 15 start-page: 3069 year: 2019 end-page: 3078 article-title: Sex differences in psychoeducation for patients with depression: a comparison of frequency and efficacy of psychoeducation publication-title: Neuropsychiatr Dis Treat – volume: 296 start-page: 208 issue: 2021 year: 2022 end-page: 215 article-title: Sex differences in neurocognitive and psychosocial functioning in bipolar disorder publication-title: J Affect Disord – volume: 55 start-page: 20 year: 2022 end-page: 21 article-title: Precision psychotherapy publication-title: Eur Neuropsychopharmacol – volume: 122 start-page: 499 issue: 6 year: 2010 end-page: 506 article-title: Neurocognitive dysfunction and psychosocial outcome in patients with bipolar I disorder at 15 year follow‐up publication-title: Acta Psychiatr Scand – volume: 9 issue: November year: 2018 article-title: Toward precision psychiatry in bipolar disorder: staging 2.0 publication-title: Front Psych – ident: e_1_2_11_13_1 doi: 10.1111/j.1600‐0447.2010.01590.x – volume-title: Diagnostic and Statistical Manual of Mental Disorders: Test Revision DSM‐IV‐TR. Fourth year: 2000 ident: e_1_2_11_24_1 – ident: e_1_2_11_33_1 doi: 10.2466/pms.1958.8.3.271 – ident: e_1_2_11_31_1 doi: 10.1037/h0054651 – volume-title: California Verbal Learning Test year: 1987 ident: e_1_2_11_35_1 – volume-title: ECDEU Assessment Manual for Psychopharmacology ‐ Revised year: 1976 ident: e_1_2_11_28_1 – ident: e_1_2_11_50_1 doi: 10.1016/j.euroneuro.2023.06.006 – ident: e_1_2_11_17_1 doi: 10.1155/2014/418432 – ident: e_1_2_11_42_1 doi: 10.1016/j.jad.2017.12.038 – ident: e_1_2_11_43_1 doi: 10.1016/j.jad.2014.02.034 – ident: e_1_2_11_45_1 doi: 10.1037/a0029299 – ident: e_1_2_11_26_1 doi: 10.1136/jnnp.23.1.56 – ident: e_1_2_11_37_1 doi: 10.1186/1745‐0179‐3‐5 – ident: e_1_2_11_40_1 doi: 10.3233/WOR‐2012‐1402 – ident: e_1_2_11_18_1 doi: 10.1016/j.jad.2008.10.023 – ident: e_1_2_11_15_1 doi: 10.1016/j.jad.2013.10.044 – ident: e_1_2_11_21_1 doi: 10.1002/wps.20351 – ident: e_1_2_11_49_1 doi: 10.1016/j.jad.2021.08.125 – ident: e_1_2_11_51_1 doi: 10.1016/j.euroneuro.2023.03.001 – ident: e_1_2_11_11_1 doi: 10.1016/j.jad.2011.04.055 – ident: e_1_2_11_41_1 doi: 10.1080/165019701750098902 – ident: e_1_2_11_10_1 doi: 10.1176/appi.ajp.2007.05081484 – volume: 14 start-page: 335 issue: 4 year: 1986 ident: e_1_2_11_27_1 article-title: Relation between the validity and reliability of the Castillian version of the Hamilton rating scale for depression publication-title: Actas Luso Esp Neurol Psiquiatr Cienc Afines – ident: e_1_2_11_48_1 doi: 10.3109/00048670903446882 – ident: e_1_2_11_19_1 doi: 10.1176/appi.ajp.2012.12070971 – ident: e_1_2_11_6_1 doi: 10.1097/NMD.0000000000001224 – ident: e_1_2_11_22_1 doi: 10.1192/bjp.bp.114.162123 – ident: e_1_2_11_9_1 doi: 10.3109/09540261.2010.514601 – ident: e_1_2_11_7_1 doi: 10.1016/j.jad.2021.09.066 – ident: e_1_2_11_8_1 doi: 10.1037/a0022677 – ident: e_1_2_11_12_1 doi: 10.2217/whe.11.71 – ident: e_1_2_11_16_1 doi: 10.1017/S1355617721001442 – ident: e_1_2_11_23_1 doi: 10.3389/fpsyt.2018.00641 – volume-title: Wisconsin Card Sorting Test Manual year: 1993 ident: e_1_2_11_30_1 – ident: e_1_2_11_4_1 doi: 10.1016/j.euroneuro.2010.08.001 – volume-title: Wechsler Adult Intelligence Scale‐III (WAIS‐III) year: 1997 ident: e_1_2_11_29_1 – ident: e_1_2_11_38_1 doi: 10.1017/CBO9781107415867 – ident: e_1_2_11_5_1 doi: 10.1111/acps.12894 – ident: e_1_2_11_39_1 doi: 10.1016/j.jad.2014.11.058 – ident: e_1_2_11_3_1 doi: 10.1016/j.jad.2009.05.014 – volume-title: Multilingual Aphasia Examination Manual year: 1976 ident: e_1_2_11_32_1 – ident: e_1_2_11_20_1 doi: 10.2174/1745017901107010112 – volume-title: Conners' Continuous Performance Test II year: 2004 ident: e_1_2_11_36_1 – ident: e_1_2_11_44_1 doi: 10.2147/NDT.S207544 – ident: e_1_2_11_14_1 doi: 10.1017/S0033291715001713 – ident: e_1_2_11_47_1 doi: 10.1017/S0033291709991644 – ident: e_1_2_11_25_1 doi: 10.1192/bjp.133.5.429 – ident: e_1_2_11_2_1 doi: 10.1016/j.euroneuro.2019.04.002 – ident: e_1_2_11_46_1 doi: 10.1080/10503307.2015.1072285 – volume-title: Test de copia de la figura compleja (The Rey–Osterrieth Complex Figure) year: 1997 ident: e_1_2_11_34_1 – ident: e_1_2_11_52_1 doi: 10.1016/j.euroneuro.2021.10.771
SSID	ssj0005108
Score	2.453836
Snippet	Background Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive... Functional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive variables are... BackgroundFunctional recovery remains a core clinical objective for patients with bipolar disorder (BD). Sociodemographic, clinical, and neurocognitive...
SourceID	proquest pubmed crossref wiley
SourceType	Aggregation Database Index Database Publisher
StartPage	543
SubjectTerms	Bipolar disorder Cognition Females functional remediation Gender differences Males psychosocial functioning Recovery of function Sex differences Social interactions Sociodemographics
Title	The impact of sex in the effectiveness of functional remediation in bipolar disorder
URI	https://onlinelibrary.wiley.com/doi/abs/10.1111%2Facps.13748 https://www.ncbi.nlm.nih.gov/pubmed/39243167 https://www.proquest.com/docview/3123585306 https://www.proquest.com/docview/3101794628
Volume	150
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dS8MwED_GHsQXvz-mUyL6JHSsTT_BlzGVISiiG-xFStMkMIRuuA3Ev967pN2cgqBvhaRNmsvd_S65_AJwIchtiCBxVBLSFWZt4QiMwRyNzk2FMaelJ8q2eAh7A_9uGAxrcFWdhbH8EIsFN9IMY69JwTMx_aLkWT6ZtlxiT0ED7PKQiPOvn5bcUTjZrBnGeBlDwGHJTUppPMtXV73RD4i5iliNy7ndhJeqszbT5LU1n4lW_vGNx_G_f7MFGyUWZR07ebahpoodWLsvd9t3oY9ziNljlGys2VS9s1HBEDEymwVSGkoqI_doVxUZLThKK3CqLkYTip6ZLGk-92Bwe9Pv9pzyFgYnp0utHMnDTISZSnSEzt-PVeYSgYtI3CTRHAEGlyFXOlci9t08agdKRb6UGGa6rtIe5_tQL8aFOgSWC-V7MtJt2dYIXLSQwosRAwrsdByruAHnlTTSiSXbSKsghQYoNQPUgGYlqLRUuGnKzZnfAAOgBpwtilFVaP8jK9R4TnWM-Qk9_MSBFfCiGYSJhhSgAZdGTL-0n3a6j8_m6egvlY9h3UNAZFNhmlCfvc3VCQKamTg1E_cTya3wHw
linkProvider	Wiley-Blackwell
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LSwMxEB60gnrx_ahWjehJ2LKvbnePpVqqtkW0hd6WzSaBImyLbUH89c4k29YqCHpbSPaVmcl8M5l8Abjm5DZ4JbJkFNARZja3OMZglkLnJoPQo9QTVVt0gmbPf-hX-nltDu2FMfwQ84QbWYaer8nAKSH9xcqTdDQuO0SfsgprtEBHdnn7vGCPQnUzEzFGzBgE9nN2UirkWdy77I9-gMxlzKqdTmPbnKw61lyFVGvyWp5OeDn9-Mbk-O__2YGtHI6ymtGfXViR2R6st_MF933oohoxs5OSDRUby3c2yBiCRmYKQfK5ktrIQ5rEIqOcozAyp-58MKIAmomc6fMAeo27br1p5QcxWCmda2UJL0h4kMhIVdH_-6FMHOJw4ZETRcpDjOGJwJMqlTz0nbRqV6Ss-kJgpOk4UrmedwiFbJjJY2Apl74rqsoWtkLsorjgbogwkONHh6EMi3A1E0c8Mnwb8SxOoQGK9QAVoTSTVJzb3Dj29LbfCsZARbicN6O10BJIksnhlProGShw8RFHRsLz1yBS1LwARbjRcvrl_XGt_vSir07-0vkCNprdditu3XceT2HTRXxkKmNKUJi8TeUZ4psJP9da_AnO1PQ8
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3rS8MwED_mhOEX34_5jOgnoaOvdS34RabD5xi6wb5IaZoEhtANt4H413uXtNMpCPqtkLRJc7nc7y6XXwBOOZkNXo8sGQV0hZnNLY4-mKXQuMkg9Cj0RNkW7eC659_26_0SnBdnYQw_xCzgRpqh12tS8JFQX5Q8SUfjmkPsKQuw6AfoXhEkevwkj8LZZtZhdJjRB-zn5KSUx_P57rw5-oEx5yGrtjmtFXguemtSTV5q0wmvpe_fiBz_-zursJyDUXZhZs8alGS2DpWHfLt9A7o4iZg5R8mGio3lGxtkDCEjM2kg-UpJZWQfTViRUcRRGIlTdT4YkfvMRM7zuQm91lW3eW3l1zBYKd1qZQkvSHiQyEg10Pr7oUwcYnDhkRNFykOE4YnAkyqVPPSdtGHXpWz4QqCf6ThSuZ63BeVsmMkdYCmXvisayha2QuSiuOBuiCCQY6fDUIZVOCmkEY8M20ZceCk0QLEeoCrsF4KKc40bx54-9FtHD6gKx7Ni1BXaAEkyOZxSHb3-BC5-YtsIeNYM4kTNClCFMy2mX9qPL5qdJ_20-5fKR1DpXLbi-5v23R4suQiOTFrMPpQnr1N5gOBmwg_1HP4AANfy6w
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+impact+of+sex+in+the+effectiveness+of+functional+remediation+in+bipolar+disorder&rft.jtitle=Acta+psychiatrica+Scandinavica&rft.au=Serra%E2%80%90Navarro%2C+Maria&rft.au=Clougher%2C+Derek&rft.au=Sol%C3%A9%2C+Brisa&rft.au=S%C3%A1nchez%E2%80%90Moreno%2C+Jose&rft.date=2024-12-01&rft.issn=0001-690X&rft.eissn=1600-0447&rft.volume=150&rft.issue=6&rft.spage=543&rft.epage=561&rft_id=info:doi/10.1111%2Facps.13748&rft.externalDBID=n%2Fa&rft.externalDocID=10_1111_acps_13748
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0001-690X&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0001-690X&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0001-690X&client=summon