Integrated Computational and Functional Screening Identifies G9a Inhibitors for SETD2 -mutant Leukemia - Zhang, Ya; Xia, Mengfang; Yi, Zhenyi; Sui, Pinpin; He, Xudong; Wang, Liping; Chen, Qiyi; Zhu, Hong-Hu; Huang, Gang; Wang, Qian-Fei (Genomics, proteomics & bioinformatics, 2025)
Keywords: Antineoplastic Agents - pharmacology; Cell Line, Tumor; Computational Biology; Enzyme Inhibitors - pharmacology; Histocompatibility Antigens - genetics; Histocompatibility Antigens - metabolism; Histone-Lysine N-Methyltransferase - antagonists & inhibitors; Histone-Lysine N-Methyltransferase - genetics; Histone-Lysine N-Methyltransferase - metabolism; Humans; Leukemia - drug therapy; Leukemia - genetics; MicroRNAs - genetics; MicroRNAs - metabolism; Mutation; Original Research; Proto-Oncogene Proteins c-myc - genetics; Proto-Oncogene Proteins c-myc - metabolism; G9a inhibitor; let-7a; MYC; L1000; SETD2-mutant leukemia