FDG PET-CT in Clinical Management of a Rare Case of Primary Hepatic Lymphoma: Role and Challenges
The common differential diagnoses for multiple space-occupying hepatic lesions (SOL) are metastases, multifocal hepatocellular carcinoma, and abscess. Primary hepatic lymphomas are rare entities that present many challenges with regard to their management. Fluorodeoxyglucose positron emission tomogr...
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| Published in | World journal of nuclear medicine Vol. 22; no. 4; pp. 297 - 299 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
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Germany
Thieme Medical and Scientific Publishers Pvt. Ltd
01.12.2023
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| Online Access | Get full text |
| ISSN | 1450-1147 1607-3312 |
| DOI | 10.1055/s-0043-1774734 |
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| Abstract | The common differential diagnoses for multiple space-occupying hepatic lesions (SOL) are metastases, multifocal hepatocellular carcinoma, and abscess. Primary hepatic lymphomas are rare entities that present many challenges with regard to their management. Fluorodeoxyglucose positron emission tomography-computed tomography is extensively used for the staging and response assessment of lymphomas but it can be challenging and difficult to interpret in cases with isolated liver involvement. We hereby present the case of an 82-year-old lady who presented with multiple liver SOL. |
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| AbstractList | The common differential diagnoses for multiple space-occupying hepatic lesions (SOL) are metastases, multifocal hepatocellular carcinoma, and abscess. Primary hepatic lymphomas are rare entities that present many challenges with regard to their management. Fluorodeoxyglucose positron emission tomography-computed tomography is extensively used for the staging and response assessment of lymphomas but it can be challenging and difficult to interpret in cases with isolated liver involvement. We hereby present the case of an 82-year-old lady who presented with multiple liver SOL. The common differential diagnoses for multiple space-occupying hepatic lesions (SOL) are metastases, multifocal hepatocellular carcinoma, and abscess. Primary hepatic lymphomas are rare entities that present many challenges with regard to their management. Fluorodeoxyglucose positron emission tomography-computed tomography is extensively used for the staging and response assessment of lymphomas but it can be challenging and difficult to interpret in cases with isolated liver involvement. We hereby present the case of an 82-year-old lady who presented with multiple liver SOL.The common differential diagnoses for multiple space-occupying hepatic lesions (SOL) are metastases, multifocal hepatocellular carcinoma, and abscess. Primary hepatic lymphomas are rare entities that present many challenges with regard to their management. Fluorodeoxyglucose positron emission tomography-computed tomography is extensively used for the staging and response assessment of lymphomas but it can be challenging and difficult to interpret in cases with isolated liver involvement. We hereby present the case of an 82-year-old lady who presented with multiple liver SOL. |
| Author | Gupta, Naveen Sharma, Lalit Mohan Malhotra, Hemant Jain, Tarun Kumar |
| AuthorAffiliation | 2 Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India 1 Department of Nuclear Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India |
| AuthorAffiliation_xml | – name: 2 Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India – name: 1 Department of Nuclear Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India |
| Author_xml | – sequence: 1 givenname: Tarun Kumar orcidid: 0000-0001-8494-2123 surname: Jain fullname: Jain, Tarun Kumar organization: Department of Nuclear Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India – sequence: 2 givenname: Naveen surname: Gupta fullname: Gupta, Naveen organization: Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India – sequence: 3 givenname: Hemant surname: Malhotra fullname: Malhotra, Hemant organization: Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India – sequence: 4 givenname: Lalit Mohan surname: Sharma fullname: Sharma, Lalit Mohan organization: Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India |
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| Cites_doi | 10.1102/1470-7330.2010.0028 10.1186/s43055-019-0011-1 10.1007/s12288-013-0263-2 10.3748/wjg.v18.i48.7409 10.7869/tg.239 10.1200/JCO.2008.18.5413 10.1007/s00261-016-0800-1 10.1186/s43055-022-00899-6 10.1159/000511248 10.4103/1450-1147.167581 |
| ContentType | Journal Article |
| Copyright | The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ). The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( ) 2023 The Author(s). |
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| Keywords | SUVmax response assessment FDG PET-CT primary hepatic lymphomas Deauville score |
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| References | D Albano (ref7) 2016; 41 W K Chan (ref3) 2008; 26 S Mrabet (ref2) 2020; 14 N Seshadri (ref6) 2010; 10 A IA Othman (ref8) 2019; 50 A Mastoraki (ref10) 2014; 30 H Y Elhamady (ref9) 2022; 53 B Pan (ref5) 2012; 18 R K Padhan (ref1) 2015; 36 S Mahajan (ref4) 2016; 15 |
| References_xml | – volume: 10 start-page: 194 issue: 01 year: 2010 ident: ref6 article-title: Primary hepatic (extranodal) lymphoma: utility of [(18)F]fluorodeoxyglucose-PET/CT publication-title: Cancer Imaging doi: 10.1102/1470-7330.2010.0028 – volume: 50 start-page: 29 year: 2019 ident: ref8 article-title: Beyond lymph nodes: 18F-FDG PET/CT in detection of unusual sites of extranodal lymphoma publication-title: Egypt J Radiol Nucl Med doi: 10.1186/s43055-019-0011-1 – volume: 30 start-page: 150 issue: 03 year: 2014 ident: ref10 article-title: Primary hepatic lymphoma: dilemmas in diagnostic approach and therapeutic management publication-title: Indian J Hematol Blood Transfus doi: 10.1007/s12288-013-0263-2 – volume: 18 start-page: 7409 issue: 48 year: 2012 ident: ref5 article-title: 18F-fluorodeoxyglucose PET/CT findings of a solitary primary hepatic lymphoma: a case report publication-title: World J Gastroenterol doi: 10.3748/wjg.v18.i48.7409 – volume: 36 start-page: 14 issue: 01 year: 2015 ident: ref1 article-title: Primary hepatic lymphoma publication-title: Trop Gastroenterol doi: 10.7869/tg.239 – volume: 26 start-page: 5479 issue: 33 year: 2008 ident: ref3 article-title: Positron emission tomography/computed tomography in the diagnosis of multifocal primary hepatic lymphoma publication-title: J Clin Oncol doi: 10.1200/JCO.2008.18.5413 – volume: 41 start-page: 1956 issue: 10 year: 2016 ident: ref7 article-title: 18F-FDG PET/CT and primary hepatic MALT: a case series publication-title: Abdom Radiol (NY) doi: 10.1007/s00261-016-0800-1 – volume: 53 start-page: 217 year: 2022 ident: ref9 article-title: Deauville score versus ratio Deauville score in the interpretation of interim 18F-FDG PET-CT and in prediction of outcome in children with FDG-avid extra-nodal lymphomas publication-title: Egypt J Radiol Nucl Med doi: 10.1186/s43055-022-00899-6 – volume: 14 start-page: 632 issue: 03 year: 2020 ident: ref2 article-title: Primary hepatic lymphoma in a patient with chronic hepatitis B publication-title: Case Rep Gastroenterol doi: 10.1159/000511248 – volume: 15 start-page: 142 issue: 02 year: 2016 ident: ref4 article-title: Detection of diffuse infiltrative primary hepatic lymphoma on FDG PET-CT: hallmarks of hepatic superscan publication-title: World J Nucl Med doi: 10.4103/1450-1147.167581 |
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| Title | FDG PET-CT in Clinical Management of a Rare Case of Primary Hepatic Lymphoma: Role and Challenges |
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