Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer

Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and b...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of polymeric materials Vol. 69; no. 2; pp. 85 - 126
Main Authors Espinoza, Sergio Miguel, Patil, Harshal Indrabhan, San Martin Martinez, Eduardo, Casañas Pimentel, Rocio, Ige, Pradum Pundlikrao
Format Journal Article
LanguageEnglish
Published Taylor & Francis 22.01.2020
Subjects
cancer
drug delivery systems
Nanomedicine
poly-ε-caprolactone
polymeric nanostructures
Online AccessGet full text
ISSN0091-4037
1563-535X
DOI10.1080/00914037.2018.1539990

Cover

Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.
AbstractList Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.
Author Patil, Harshal Indrabhan
Ige, Pradum Pundlikrao
Espinoza, Sergio Miguel
San Martin Martinez, Eduardo
Casañas Pimentel, Rocio
Author_xml – sequence: 1
  givenname: Sergio Miguel
  surname: Espinoza
  fullname: Espinoza, Sergio Miguel
  organization: Instituto Politécnico Nacional, Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada
– sequence: 2
  givenname: Harshal Indrabhan
  surname: Patil
  fullname: Patil, Harshal Indrabhan
  organization: Department of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur
– sequence: 3
  givenname: Eduardo
  surname: San Martin Martinez
  fullname: San Martin Martinez, Eduardo
  organization: Instituto Politécnico Nacional, Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada
– sequence: 4
  givenname: Rocio
  orcidid: 0000-0003-3184-9675
  surname: Casañas Pimentel
  fullname: Casañas Pimentel, Rocio
  email: rgcasanaspi@conacyt.mx
  organization: CONACYT-Instituto Politécnico Nacional, Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada
– sequence: 5
  givenname: Pradum Pundlikrao
  orcidid: 0000-0001-8709-5767
  surname: Ige
  fullname: Ige, Pradum Pundlikrao
  email: pradyumna_1978@rediffmail.com
  organization: Department of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur
BookMark eNqFkMFKAzEURYNUsFY_QchSwalJM2lndKMUq0LBLhTcDW_eJBqZSYZkinTlV_kbfpOprRsXukpuuPe-l7NPetZZRcgRZ0POMnbGWM5TJibDEePZkEuR5znbIX0uxyKRQj71SH_tSdamPbIfwitjXMgs75P3hatXyedHgtB6VwN2sZseL6bzk1MKNL41Jhj7TNvoa5Sn2nnavoBvANWyMwg1BVvR0rhGVRvZtnW8dMbZcE5nDpeBOkst2I3FxAHGUgSLyh-QXQ11UIfbc0AeZ9cP09tkfn9zN72aJyg465IsywHGgGmZa8UkxzKNH1LjSSm5LjOFKeJIoyx5mko-0pWqlCorZHnUWozEgFxsetG7ELzSBZrue8fOg6kLzoo1y-KHZbFmWWxZxrT8lW69acCv_s1dbnLGRm4NvDlfV0UHq9p57SMAEwrxd8UXHMSQ1A
CitedBy_id crossref_primary_10_1080_09205063_2022_2161780
crossref_primary_10_1016_j_mtchem_2023_101376
crossref_primary_10_1007_s12221_024_00516_5
crossref_primary_10_1002_pol_20210858
crossref_primary_10_3390_polym14235278
crossref_primary_10_3390_ijms24032945
crossref_primary_10_1002_pen_25776
crossref_primary_10_3390_polym16172400
crossref_primary_10_1016_j_pnsc_2020_10_001
crossref_primary_10_1155_2022_6449607
crossref_primary_10_3390_polym12030512
crossref_primary_10_1016_j_compositesa_2021_106494
crossref_primary_10_1016_j_bioactmat_2022_04_027
crossref_primary_10_1021_acsapm_1c01307
crossref_primary_10_3390_ijms251910692
crossref_primary_10_1007_s13726_024_01449_9
crossref_primary_10_1080_00914037_2023_2277222
crossref_primary_10_1016_j_jddst_2023_104300
crossref_primary_10_1016_j_matlet_2022_133062
crossref_primary_10_1016_j_xphs_2023_08_025
crossref_primary_10_1016_j_ijpharm_2025_125340
crossref_primary_10_1016_j_mtcomm_2021_102455
crossref_primary_10_3390_ma13030570
crossref_primary_10_1002_chem_202401727
crossref_primary_10_1134_S1061933X23600744
crossref_primary_10_1007_s13346_020_00736_1
crossref_primary_10_3390_nano13152163
crossref_primary_10_3390_molecules26071870
crossref_primary_10_3390_ma17091973
crossref_primary_10_1021_acsmaterialsau_3c00013
crossref_primary_10_1016_j_jmbbm_2022_105418
crossref_primary_10_1002_app_54759
crossref_primary_10_1016_j_jddst_2025_106754
crossref_primary_10_3390_polym15061554
crossref_primary_10_1016_j_lfs_2021_119927
crossref_primary_10_1016_j_jtice_2020_11_003
crossref_primary_10_1016_j_ccr_2022_214701
crossref_primary_10_3390_ma16062364
crossref_primary_10_1002_adfm_202010284
crossref_primary_10_1515_polyeng_2022_0261
crossref_primary_10_3390_ijms22062792
crossref_primary_10_3390_macromol3030026
crossref_primary_10_1007_s12035_023_03540_3
crossref_primary_10_1016_j_jpba_2021_114182
crossref_primary_10_1016_j_ijpharm_2022_122363
crossref_primary_10_3390_polym14050983
crossref_primary_10_1021_acs_orglett_9b02830
crossref_primary_10_3390_polym14214702
crossref_primary_10_18778_1730_2366_16_10
crossref_primary_10_1016_j_msec_2021_112489
crossref_primary_10_1021_acs_joc_2c01062
crossref_primary_10_1038_s41598_020_78977_w
crossref_primary_10_1002_mabi_202300075
crossref_primary_10_1021_acs_jafc_0c03645
crossref_primary_10_1002_adfm_202300501
crossref_primary_10_3390_bioengineering8010001
crossref_primary_10_1080_00914037_2022_2075870
crossref_primary_10_1039_D2CP01273A
crossref_primary_10_2174_0929867330666230120163543
crossref_primary_10_3390_nano10040656
crossref_primary_10_1002_pen_26810
crossref_primary_10_3390_pharmaceutics14040873
crossref_primary_10_1016_j_eurpolymj_2020_109789
crossref_primary_10_1039_D2PY00115B
crossref_primary_10_1007_s00289_021_03865_w
crossref_primary_10_1021_acsapm_3c01270
crossref_primary_10_1080_10601325_2020_1831392
crossref_primary_10_1016_j_polymertesting_2020_106998
crossref_primary_10_3390_ijms21197312
crossref_primary_10_3390_polym12010137
crossref_primary_10_1007_s00347_022_01673_9
crossref_primary_10_1016_j_ijpharm_2021_120846
crossref_primary_10_1088_2057_1976_abeb5a
crossref_primary_10_3390_nano10091696
crossref_primary_10_3390_pharmaceutics14071522
crossref_primary_10_3390_ijms232315393
crossref_primary_10_4103_jcrt_jcrt_278_22
crossref_primary_10_1038_s41598_024_53548_5
crossref_primary_10_1038_s41598_024_54157_y
crossref_primary_10_1615_CritRevBiomedEng_2023043780
crossref_primary_10_31857_S0023291223600463
crossref_primary_10_1080_10837450_2020_1864643
crossref_primary_10_1039_D4RA01178C
crossref_primary_10_3390_pharmaceutics14122709
crossref_primary_10_3390_chemengineering7060104
crossref_primary_10_1016_j_fbio_2025_105884
crossref_primary_10_3390_su132212856
crossref_primary_10_1016_j_molstruc_2021_131459
crossref_primary_10_3390_polym14183736
crossref_primary_10_1016_j_ijpharm_2024_124734
crossref_primary_10_3390_jfb12040055
crossref_primary_10_1007_s12221_022_4275_0
crossref_primary_10_1088_2399_7532_abc735
crossref_primary_10_3390_pharmaceutics16030317
crossref_primary_10_1039_D0RA04997B
crossref_primary_10_3390_nanomanufacturing4010002
crossref_primary_10_1080_26889277_2022_2053302
Cites_doi 10.3109/10717544.2014.948643
10.1016/j.biomaterials.2013.08.036
10.1021/cn100114k
10.1016/j.biomaterials.2012.05.020
10.1016/j.polymer.2013.04.045
10.1016/j.matpr.2016.11.036
10.1002/app.41768">10.1002/app.41768
10.1016/j.ijpharm.2009.06.007
10.1016/j.ijpharm.2010.10.005
10.2147/IJN.S33602">10.2147/IJN.S33602
10.1016/j.colsurfa.2010.01.037
10.1016/j.ijpharm.2009.04.007
10.1016/j.jpcs.2007.09.016
10.1016/j.msec.2012.12.015
10.1016/j.ijbiomac.2016.11.098
10.1002/app.1981.070261124
10.2147/IJN.S108143
10.1039/C4TB00273C
10.1002/adem.201180035
10.3109/02652049609006801
10.1177/155892501400900309
10.1039/C5NR04963F
10.1002/polb.22259
10.2147/IJN.S75186">10.2147/IJN.S75186
10.1166/jbn.2014.1835
10.1016/j.progpolymsci.2007.05.017
10.1016/S0141-3910(99)00145-7
10.1186/1556-276X-6-260
10.1166/jbn.2014.1746
10.1002/jps.22266
10.3390/ph5101092
10.2174/156800908786241050
10.1016/S0378-5173(02)00483-0
10.2174/156652412803833508
10.1016/j.ijpharm.2007.05.040
10.1016/j.biomaterials.2012.07.046
10.1093/abbs/gmt063
10.1016/S0168-3659(03)00367-5
10.1021/mp300350e
10.1016/j.biomaterials.2013.09.001
10.5732/cjc.012.10280
10.3923/rjnn.2010
10.1016/j.bej.2012.02.005
10.1007/BF00701240
10.1007/s10549-012-2289-9
10.1016/j.jconrel.2007.02.013
10.1529/biophysj.106.098715
10.1016/j.ijpharm.2012.11.034
10.1016/j.biomaterials.2012.10.068
10.1016/j.ijpharm.2008.12.015
10.2147/IJN.S25251">10.2147/IJN.S25251
10.1016/j.ijpharm.2014.11.029
10.1007/s13311-017-0520-4
10.1038/sj.onc.1210797
10.3390/polym5020361
10.1007/s10924-006-0041-4
10.3109/02652048.2011.576785
10.1093/nar/gkx1089
10.1109/TNB.2016.2612340
10.1016/j.nano.2015.10.022
10.3109/21691401.2015.1101000
10.1016/j.colsurfb.2009.03.010
10.2147/IJN.S34886">10.2147/IJN.S34886
10.1007/978-94-007-0344-5_1
10.2147/IJN.S123422
10.1002/jbm.820190408
10.1016/j.ijpharm.2014.05.014
10.1073/pnas.1114518108
10.1039/C4BM00134F
10.1021/np800191t
10.1016/j.progpolymsci.2010.04.002
10.2147/IJN.S16570">10.2147/IJN.S16570
10.1021/bm400378x
10.1016/S1535-6108(03)00273-3
10.1016/j.jconrel.2012.05.003
10.1093/abbs/gmr011
10.1016/j.biomaterials.2011.07.069
10.1002/pat.1992.220030611
10.1039/C6RA04687H
10.1002/jps.24548
10.1016/S1734-1140(12)70901-5
10.1007/s11671-009-9431-6
10.1016/S0141-3910(02)00393-2
10.1016/S0032-3861(98)00414-5
10.1021/mp1002653
10.1080/02652040110055270
10.1158/0008-5472
10.1155/2014/498420
10.1080/10611860701453901
10.1016/j.jconrel.2011.11.031
10.1016/j.biocel.2011.01.020
10.1038/srep26546">10.1038/srep26546
10.1016/j.jconrel.2008.04.013
10.3892/or_00000689">10.3892/or_00000689
10.1038/s41598-017-12824-3
10.1016/S0168-3659(99)00253-9
10.1039/c7sc01905j
10.1016/S1359-6446(01)01721-4
10.1016/j.jconrel.2014.05.056
10.1517/17425247.3.1.139
10.1371/journal.pone.0024172">10.1371/journal.pone.0024172
10.2147/IJN.S45062">10.2147/IJN.S45062
10.3109/10837450.2016.1146296
10.1016/B978-0-12-396983-5.00001-6
10.1021/mp2002736
10.1016/j.colsurfb.2013.07.036
10.3390/ijms11052188
10.1021/acsnano.6b06040
10.1023/A:1005441707356
10.1016/j.biomaterials.2011.02.044
10.1158/0008-5472.CAN-06-1648
10.1002/macp.1984.021850617
10.1016/j.ejphar.2006.01.008
10.1016/j.ejpb.2010.04.016
10.3762/bjnano.8.144
10.1002/ijc.22886
10.1016/S0378-5173(99)00109-X
10.1246/cl.1993.1149">10.1246/cl.1993.1149
10.1016/j.nano.2011.11.005
10.1016/j.ejps.2017.02.026
10.1016/j.jconrel.2011.09.064
10.1016/j.canlet.2004.09.041
10.1016/j.biomaterials.2012.03.058
10.1080/10611860802102282
10.4103/2230-973X.119212
10.1155/2017/7392891
10.1369/0022155413503662
10.1002/app.1978.070220417
10.1080/10611860802095494
10.1016/j.molmed.2012.04.012
10.1007/s00280-008-0790-y
10.1038/sj.neo.7900234
10.3322/caac.21262
10.1016/j.biomaterials.2012.09.044
10.1038/sj.cgt.7700831
10.1016/0955-2863(91)90019-2
10.1016/j.ijpharm.2012.04.008
10.1021/acsbiomaterials.6b00310
10.1016/S0378-4347(97)00468-4">10.1016/S0378-4347(97)00468-4
10.1016/j.actbio.2016.06.038">10.1016/j.actbio.2016.06.038
10.1007/s11095-009-9929-8
10.1016/j.polymer.2004.11.013
10.1021/mp400644e
10.3109/1061186X.2015.1070854
10.1002/pat.1227
10.1172/JCI200320337
10.3892/or.2011.1243">10.3892/or.2011.1243
10.1016/j.biomaterials.2003.09.087
10.1038/srep02534
10.3109/21691401.2015.1008510
10.1021/bm050902y
10.1093/clinchem/39.5.746
10.1371/journal.pone.0069643">10.1371/journal.pone.0069643
10.1002/jbm.a.34735
10.1016/j.nano.2011.08.012
10.1111/bph.12344
10.1021/bc200139n
10.1039/C4BM00272E
10.1371/journal.pone.0024075">10.1371/journal.pone.0024075
10.1002/app.32266">10.1002/app.32266
10.1016/j.carbpol.2013.01.014
10.1023/A:1020450326301
10.1080/02652040400015346.
10.1039/C5RA23067E
10.1351/PAC-CON-11-10-19
10.1016/j.ijpharm.2004.01.044
10.1016/B978-0-12-396983-5.00009-0
10.1039/C2DT30276D
10.1021/mp500113p
10.1166/jnn.2011.3102
10.1016/j.ijpharm.2009.07.033
10.2165/00126839-200708030-00001
10.1007/978-3-642-19077-3_2
10.1016/j.jconrel.2011.08.017
10.1016/j.biomaterials.2004.09.052
10.1002/ddr.10396
10.1039/C4MD00348A
10.1016/S0142-9612(00)00291-X
10.1017/S1462399411001888">10.1017/S1462399411001888
10.1186/1556-276X-8-66">10.1186/1556-276X-8-66
10.1007/s11095-007-9451-9
10.2147/IJN.S76092">10.2147/IJN.S76092
10.1016/j.colsurfb.2015.04.005
10.1016/j.tranon.2015.12.005
10.1021/bm0342382
10.1593/tlo.10235
10.1089/ten.tea.2008.0025
10.1016/j.biomaterials.2005.09.019
10.1163/156856297X00380
10.1016/j.molliq.2018.02.024
10.1088/1468-6996/13/3/035002">10.1088/1468-6996/13/3/035002
10.1007/s11095-011-0440-7
10.2147/IJN.S55541">10.2147/IJN.S55541
10.1021/jp905781g
10.1002/pat.733
10.1002/masy.200650822">10.1002/masy.200650822
10.1016/j.actbio.2009.11.035
10.1016/S0141-3910(96)00208-X
10.1002/ijc.29210
10.1016/j.brainres.2008.01.039
10.1016/j.ijpharm.2012.05.015
10.1039/C5TB01939G
10.1039/C7RA09038B
10.1016/0032-3861(73)90017-7
10.1016/j.ijpharm.2011.05.014
10.1016/j.colsurfb.2009.09.001
10.1016/j.ijpharm.2010.10.015
10.1016/j.polymer.2008.06.005
10.2147/IJN.S26401">10.2147/IJN.S26401
10.1016/j.jconrel.2011.10.005
10.1016/j.biomaterials.2014.04.099
10.1016/j.lfs.2015.09.021
10.2147/IJN.S78988">10.2147/IJN.S78988
10.7150/thno.10257
10.1016/S0959-8049(01)00171-X
10.2174/187152012800228788
10.1016/j.ijpharm.2004.12.010
10.1016/j.ijpharm.2009.09.023
10.1007/s10847-014-0422-6
10.1166/jnn.2010.3617
10.1016/j.nano.2005.12.003
10.1039/B820162P
10.1002/mnfr.200900277
10.1016/j.canlet.2008.04.018
10.1021/mp3000309
10.1016/j.biopha.2016.10.095
10.1055/s-0042-112030
10.1016/j.yexmp.2008.12.004
10.1038/jcbfm.2013.41
10.2147/IJN.S45250">10.2147/IJN.S45250
10.1155/2017/9625909
10.1166/jnn.2016.10739
10.1016/j.jconrel.2009.11.002
10.1158/1078-0432.CCR-07-4973
10.1073/pnas.0408191101
10.1158/1535-7163
10.1038/aps.2016.20
10.1016/S0169-409X(02)00047-9
10.1016/j.jconrel.2013.10.002
10.1155/2014/507273
10.1016/j.colsurfb.2015.11.041
10.1016/j.ijpharm.2013.07.069
10.1093/nar/30.1.42
10.2174/092986709788803312
10.2147/IJN.S77667">10.2147/IJN.S77667
10.1016/S0032-3861(99)00586-8
10.1016/j.ejphar.2008.02.026
10.1016/S0169-409X(02)00228-4
10.1038/onc.2009.441
10.1002/cbf.1149
10.1371/journal.pone.0094309">10.1371/journal.pone.0094309
10.1021/mp400342f
10.1002/(SICI)1097-4628(19971031)66:5 < 921::AID-APP12 > 3.0.CO;2-Q
10.7314/APJCP.2013.14.1.409
10.1021/acs.biomac.6b01608
10.1016/j.ejpb.2008.06.016
10.1016/j.canlet.2009.02.018
10.1016/j.msec.2015.08.058
10.1039/C6RA03440C
10.1039/C3RA42112K
10.1039/c0nr00758g
10.1016/j.polymer.2010.10.029
10.1186/2162-3619-1-38">10.1186/2162-3619-1-38
10.1016/j.actbio.2013.04.031
10.4015/S1016237213400097">10.4015/S1016237213400097
10.1080/21691401.2016.1203793
10.1016/j.ejpb.2012.04.021
10.1016/j.jconrel.2015.08.021
10.5599/admet.3.2.167">10.5599/admet.3.2.167
10.1016/j.ejps.2015.10.021
10.2147/IJN.S26697">10.2147/IJN.S26697
ContentType Journal Article
Copyright 2019 Taylor & Francis Group, LLC 2019
Copyright_xml – notice: 2019 Taylor & Francis Group, LLC 2019
DBID AAYXX
CITATION
DOI 10.1080/00914037.2018.1539990
DatabaseName CrossRef
DatabaseTitle CrossRef
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
Discipline Engineering
Chemistry
EISSN 1563-535X
EndPage 126
ExternalDocumentID 10_1080_00914037_2018_1539990
1539990
Genre Article
GroupedDBID -~X
.7F
.QJ
0BK
0R~
29J
30N
4.4
5GY
5VS
AAENE
AAJMT
AALDU
AAMIU
AAPUL
AAQRR
ABDBF
ABFIM
ABHAV
ABJNI
ABLIJ
ABPAQ
ABPEM
ABXUL
ABXYU
ACGEJ
ACGFS
ACGOD
ACIWK
ACTIO
ADCVX
ADGTB
ADXPE
AEISY
AENEX
AEOZL
AEPSL
AEYOC
AFKVX
AGDLA
AGMYJ
AHDZW
AIJEM
AJWEG
AKBVH
AKOOK
ALMA_UNASSIGNED_HOLDINGS
ALQZU
AQRUH
AVBZW
AWYRJ
BLEHA
CCCUG
CE4
CS3
DGEBU
DKSSO
DU5
EAP
EBS
EMK
EPL
EST
ESX
E~A
E~B
GCUZY
GTTXZ
H13
HF~
HZ~
H~P
I-F
IPNFZ
J.P
KYCEM
LJTGL
M4Z
ML~
NA5
NW0
O9-
P2P
PQQKQ
RIG
RNANH
ROSJB
RTWRZ
S-T
SNACF
TBQAZ
TCY
TDBHL
TFL
TFT
TFW
TTC
TTHFI
TUROJ
TUS
TWF
UT5
UU3
WH7
ZGOLN
~S~
AAGDL
AAHIA
AAYXX
ADYSH
AFRVT
AIYEW
AMPGV
CITATION
ID FETCH-LOGICAL-c310t-889aa6ac4b9fe051cb4091e67b51fb8ec4cc2fc5b144512fdedeebdc09445f323
ISSN 0091-4037
IngestDate Thu Apr 24 23:01:13 EDT 2025
Tue Jul 01 04:38:33 EDT 2025
Wed Dec 25 09:09:22 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 2
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c310t-889aa6ac4b9fe051cb4091e67b51fb8ec4cc2fc5b144512fdedeebdc09445f323
ORCID 0000-0001-8709-5767
0000-0003-3184-9675
PageCount 42
ParticipantIDs crossref_citationtrail_10_1080_00914037_2018_1539990
informaworld_taylorfrancis_310_1080_00914037_2018_1539990
crossref_primary_10_1080_00914037_2018_1539990
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 1/22/2020
2020-01-22
PublicationDateYYYYMMDD 2020-01-22
PublicationDate_xml – month: 01
  year: 2020
  text: 1/22/2020
  day: 22
PublicationDecade 2020
PublicationTitle International journal of polymeric materials
PublicationYear 2020
Publisher Taylor & Francis
Publisher_xml – name: Taylor & Francis
References Wagner F. S (CIT0057) 1991; 1
CIT0230
CIT0111
CIT0232
CIT0110
CIT0231
CIT0113
CIT0234
CIT0112
CIT0233
CIT0115
CIT0236
CIT0114
CIT0235
Dhanaraju M. D. (CIT0090) 2010; 5
CIT0117
CIT0238
CIT0237
CIT0119
CIT0118
CIT0239
CIT0120
CIT0241
CIT0240
CIT0122
CIT0243
CIT0121
CIT0242
CIT0003
CIT0124
CIT0245
CIT0002
CIT0123
CIT0244
CIT0005
CIT0126
CIT0247
CIT0125
CIT0246
CIT0007
CIT0128
CIT0249
CIT0006
CIT0127
CIT0248
CIT0009
CIT0008
CIT0129
Forman D. (CIT0012) 2014
CIT0250
CIT0010
CIT0131
CIT0252
CIT0130
CIT0251
CIT0133
CIT0254
CIT0011
CIT0132
CIT0253
CIT0014
CIT0135
CIT0256
CIT0013
CIT0134
CIT0255
CIT0137
CIT0258
CIT0015
CIT0136
CIT0257
CIT0018
CIT0139
CIT0017
CIT0138
CIT0259
CIT0019
CIT0140
CIT0261
CIT0260
CIT0021
CIT0142
CIT0263
CIT0020
CIT0141
CIT0262
CIT0023
CIT0144
CIT0265
CIT0022
CIT0143
CIT0264
CIT0025
CIT0146
CIT0267
CIT0024
CIT0145
CIT0266
CIT0027
CIT0148
CIT0269
CIT0026
CIT0147
CIT0268
CIT0028
CIT0149
Cama G. (CIT0067) 2016
Lide D. R (CIT0055) 2003
CIT0209
CIT0208
CIT0200
CIT0203
CIT0202
CIT0205
CIT0204
CIT0206
CIT0210
CIT0219
CIT0212
CIT0211
CIT0214
CIT0213
CIT0216
CIT0215
CIT0218
Tietz N. W. (CIT0046) 1993; 39
CIT0217
CIT0100
CIT0221
CIT0220
CIT0102
CIT0223
CIT0101
CIT0222
CIT0104
CIT0225
CIT0103
CIT0224
CIT0106
CIT0227
Guerra G. D. (CIT0083) 2011; 5
CIT0105
CIT0226
CIT0108
CIT0229
CIT0107
CIT0228
CIT0072
CIT0193
CIT0071
CIT0192
CIT0074
CIT0195
CIT0073
CIT0194
CIT0076
CIT0197
CIT0075
CIT0196
CIT0078
CIT0199
CIT0077
CIT0198
CIT0070
CIT0191
CIT0190
CIT0079
CIT0082
CIT0085
CIT0084
CIT0087
CIT0086
CIT0089
CIT0088
CIT0081
CIT0094
CIT0093
CIT0096
CIT0095
CIT0098
CIT0097
CIT0099
Jadia R. (CIT0207) 2016; 1
CIT0092
CIT0091
Maletínská L. (CIT0116) 2000; 60
Ramesh D. V (CIT0080) 2009; 23
CIT0270
CIT0030
CIT0151
CIT0272
CIT0150
CIT0271
CIT0032
CIT0153
CIT0274
CIT0031
CIT0152
CIT0273
CIT0034
CIT0155
CIT0276
CIT0033
CIT0154
CIT0275
Godage R. (CIT0001) 2017
CIT0036
CIT0157
CIT0278
CIT0035
CIT0156
CIT0277
CIT0038
CIT0159
CIT0037
CIT0158
CIT0279
CIT0039
Nakache E. (CIT0016) 1999; 5
CIT0160
CIT0281
CIT0280
CIT0041
CIT0162
CIT0283
CIT0040
CIT0161
CIT0282
CIT0043
CIT0164
CIT0285
CIT0042
CIT0163
CIT0284
CIT0045
CIT0166
CIT0044
CIT0165
Osbild S. (CIT0201) 2006; 26
CIT0286
CIT0047
CIT0168
CIT0167
CIT0049
CIT0048
CIT0169
CIT0050
CIT0171
CIT0170
CIT0052
CIT0173
CIT0051
CIT0172
CIT0054
CIT0175
CIT0053
CIT0174
CIT0056
CIT0177
CIT0176
CIT0058
CIT0179
CIT0178
CIT0059
CIT0061
CIT0182
CIT0060
CIT0181
CIT0063
CIT0184
CIT0062
CIT0183
CIT0065
CIT0186
CIT0064
CIT0185
CIT0188
CIT0066
CIT0187
CIT0180
Sivabalan A. (CIT0004) 2014; 1
Yadav B.V.N. (CIT0109) 2016; 8
CIT0069
CIT0068
CIT0189
Pitt C. G (CIT0029) 1990
References_xml – ident: CIT0151
  doi: 10.3109/10717544.2014.948643
– ident: CIT0156
  doi: 10.1016/j.biomaterials.2013.08.036
– ident: CIT0140
  doi: 10.1021/cn100114k
– ident: CIT0141
  doi: 10.1016/j.biomaterials.2012.05.020
– ident: CIT0032
  doi: 10.1016/j.polymer.2013.04.045
– volume: 5
  start-page: 121
  year: 2011
  ident: CIT0083
  publication-title: International Journal of Biology and Biomedical Engineering
– ident: CIT0269
  doi: 10.1016/j.matpr.2016.11.036
– ident: CIT0095
  doi: 10.1002/app.41768">10.1002/app.41768
– ident: CIT0226
  doi: 10.1016/j.ijpharm.2009.06.007
– ident: CIT0108
  doi: 10.1016/j.ijpharm.2010.10.005
– ident: CIT0209
  doi: 10.2147/IJN.S33602">10.2147/IJN.S33602
– ident: CIT0220
  doi: 10.1016/j.colsurfa.2010.01.037
– ident: CIT0253
  doi: 10.1016/j.ijpharm.2009.04.007
– ident: CIT0078
  doi: 10.1016/j.jpcs.2007.09.016
– ident: CIT0064
  doi: 10.1016/j.msec.2012.12.015
– ident: CIT0231
  doi: 10.1016/j.ijbiomac.2016.11.098
– ident: CIT0027
  doi: 10.1002/app.1981.070261124
– ident: CIT0175
  doi: 10.2147/IJN.S108143
– ident: CIT0286
  doi: 10.1039/C4TB00273C
– ident: CIT0101
  doi: 10.1002/adem.201180035
– ident: CIT0086
  doi: 10.3109/02652049609006801
– ident: CIT0059
  doi: 10.1177/155892501400900309
– ident: CIT0202
  doi: 10.1039/C5NR04963F
– ident: CIT0036
  doi: 10.1002/polb.22259
– ident: CIT0203
  doi: 10.2147/IJN.S75186">10.2147/IJN.S75186
– ident: CIT0235
  doi: 10.1166/jbn.2014.1835
– ident: CIT0023
  doi: 10.1016/j.progpolymsci.2007.05.017
– ident: CIT0042
  doi: 10.1016/S0141-3910(99)00145-7
– ident: CIT0278
  doi: 10.1186/1556-276X-6-260
– ident: CIT0217
  doi: 10.1166/jbn.2014.1746
– ident: CIT0079
  doi: 10.1002/jps.22266
– ident: CIT0154
  doi: 10.3390/ph5101092
– ident: CIT0169
  doi: 10.2174/156800908786241050
– ident: CIT0038
  doi: 10.1016/S0378-5173(02)00483-0
– ident: CIT0219
  doi: 10.2174/156652412803833508
– ident: CIT0094
  doi: 10.1016/j.ijpharm.2007.05.040
– ident: CIT0118
  doi: 10.1016/j.biomaterials.2012.07.046
– ident: CIT0214
  doi: 10.1093/abbs/gmt063
– ident: CIT0097
  doi: 10.1016/S0168-3659(03)00367-5
– ident: CIT0267
  doi: 10.1021/mp300350e
– ident: CIT0138
  doi: 10.1016/j.biomaterials.2013.09.001
– ident: CIT0155
  doi: 10.5732/cjc.012.10280
– ident: CIT0009
  doi: 10.3923/rjnn.2010
– ident: CIT0103
  doi: 10.1016/j.bej.2012.02.005
– ident: CIT0031
  doi: 10.1007/BF00701240
– ident: CIT0197
  doi: 10.1007/s10549-012-2289-9
– ident: CIT0282
  doi: 10.1016/j.jconrel.2007.02.013
– ident: CIT0056
  doi: 10.1529/biophysj.106.098715
– ident: CIT0264
  doi: 10.1016/j.ijpharm.2012.11.034
– ident: CIT0215
  doi: 10.1016/j.biomaterials.2012.10.068
– volume: 5
  start-page: 114
  year: 2010
  ident: CIT0090
  publication-title: Asian J. Pharm. Sci
– ident: CIT0262
  doi: 10.1016/j.ijpharm.2008.12.015
– ident: CIT0125
  doi: 10.2147/IJN.S25251">10.2147/IJN.S25251
– ident: CIT0224
  doi: 10.1016/j.ijpharm.2014.11.029
– ident: CIT0160
  doi: 10.1007/s13311-017-0520-4
– ident: CIT0234
  doi: 10.1038/sj.onc.1210797
– ident: CIT0071
  doi: 10.3390/polym5020361
– ident: CIT0039
  doi: 10.1007/s10924-006-0041-4
– ident: CIT0165
  doi: 10.3109/02652048.2011.576785
– ident: CIT0034
  doi: 10.1093/nar/gkx1089
– ident: CIT0106
  doi: 10.1109/TNB.2016.2612340
– ident: CIT0206
  doi: 10.1016/j.nano.2015.10.022
– ident: CIT0222
  doi: 10.3109/21691401.2015.1101000
– ident: CIT0114
  doi: 10.1016/j.colsurfb.2009.03.010
– ident: CIT0237
  doi: 10.2147/IJN.S34886">10.2147/IJN.S34886
– ident: CIT0104
  doi: 10.1007/978-94-007-0344-5_1
– ident: CIT0120
  doi: 10.2147/IJN.S123422
– ident: CIT0028
  doi: 10.1002/jbm.820190408
– ident: CIT0263
  doi: 10.1016/j.ijpharm.2014.05.014
– ident: CIT0137
  doi: 10.1073/pnas.1114518108
– ident: CIT0242
  doi: 10.1039/C4BM00134F
– ident: CIT0174
  doi: 10.1021/np800191t
– ident: CIT0003
  doi: 10.1016/j.progpolymsci.2010.04.002
– ident: CIT0121
  doi: 10.2147/IJN.S16570">10.2147/IJN.S16570
– ident: CIT0195
  doi: 10.1021/bm400378x
– ident: CIT0136
  doi: 10.1016/S1535-6108(03)00273-3
– ident: CIT0089
  doi: 10.1016/j.jconrel.2012.05.003
– ident: CIT0112
  doi: 10.1093/abbs/gmr011
– ident: CIT0147
  doi: 10.1016/j.biomaterials.2011.07.069
– ident: CIT0096
  doi: 10.1002/pat.1992.220030611
– ident: CIT0192
  doi: 10.1039/C6RA04687H
– ident: CIT0272
  doi: 10.1002/jps.24548
– ident: CIT0015
  doi: 10.1016/S1734-1140(12)70901-5
– ident: CIT0184
  doi: 10.1007/s11671-009-9431-6
– ident: CIT0065
  doi: 10.1016/S0141-3910(02)00393-2
– ident: CIT0040
  doi: 10.1016/S0032-3861(98)00414-5
– ident: CIT0198
  doi: 10.1021/mp1002653
– start-page: 16
  volume-title: World cancer report
  year: 2014
  ident: CIT0012
– ident: CIT0092
  doi: 10.1080/02652040110055270
– ident: CIT0205
  doi: 10.1158/0008-5472
– ident: CIT0037
  doi: 10.1155/2014/498420
– ident: CIT0277
  doi: 10.1080/10611860701453901
– ident: CIT0159
  doi: 10.1016/j.jconrel.2011.11.031
– volume-title: Advanced drug delivery systems
  year: 2017
  ident: CIT0001
– ident: CIT0232
  doi: 10.1016/j.biocel.2011.01.020
– ident: CIT0266
  doi: 10.1038/srep26546">10.1038/srep26546
– ident: CIT0183
  doi: 10.1016/j.jconrel.2008.04.013
– ident: CIT0255
  doi: 10.3892/or_00000689">10.3892/or_00000689
– ident: CIT0007
  doi: 10.1038/s41598-017-12824-3
– ident: CIT0082
  doi: 10.1016/S0168-3659(99)00253-9
– ident: CIT0245
  doi: 10.1039/c7sc01905j
– ident: CIT0105
  doi: 10.1016/S1359-6446(01)01721-4
– ident: CIT0143
  doi: 10.1016/j.jconrel.2014.05.056
– ident: CIT0021
  doi: 10.1517/17425247.3.1.139
– ident: CIT0229
  doi: 10.1371/journal.pone.0024172">10.1371/journal.pone.0024172
– ident: CIT0170
  doi: 10.2147/IJN.S45062">10.2147/IJN.S45062
– ident: CIT0173
  doi: 10.3109/10837450.2016.1146296
– ident: CIT0051
  doi: 10.1016/B978-0-12-396983-5.00001-6
– volume: 8
  start-page: 83
  year: 2016
  ident: CIT0109
  publication-title: Int. J. Pharm. Pharm. Sci
– ident: CIT0265
  doi: 10.1021/mp2002736
– ident: CIT0188
  doi: 10.1016/j.colsurfb.2013.07.036
– ident: CIT0177
  doi: 10.3390/ijms11052188
– ident: CIT0010
  doi: 10.1021/acsnano.6b06040
– ident: CIT0069
  doi: 10.1023/A:1005441707356
– ident: CIT0117
  doi: 10.1016/j.biomaterials.2011.02.044
– ident: CIT0257
  doi: 10.1158/0008-5472.CAN-06-1648
– ident: CIT0063
  doi: 10.1002/macp.1984.021850617
– ident: CIT0127
  doi: 10.1016/j.ejphar.2006.01.008
– ident: CIT0228
  doi: 10.1016/j.ejpb.2010.04.016
– ident: CIT0026
  doi: 10.3762/bjnano.8.144
– ident: CIT0258
  doi: 10.1002/ijc.22886
– ident: CIT0099
  doi: 10.1016/S0378-5173(99)00109-X
– ident: CIT0077
  doi: 10.1246/cl.1993.1149">10.1246/cl.1993.1149
– ident: CIT0191
  doi: 10.1016/j.nano.2011.11.005
– ident: CIT0163
  doi: 10.1016/j.ejps.2017.02.026
– volume: 1
  start-page: 1
  year: 2016
  ident: CIT0207
  publication-title: Int. J. Nanotechnol. Nanomed
– ident: CIT0005
  doi: 10.1016/j.jconrel.2011.09.064
– volume: 1
  start-page: 155
  volume-title: Kirk-Othmer Encyclopedia of Chemical Technology
  year: 1991
  ident: CIT0057
– ident: CIT0110
  doi: 10.1016/j.canlet.2004.09.041
– ident: CIT0148
  doi: 10.1016/j.biomaterials.2012.03.058
– ident: CIT0233
  doi: 10.1080/10611860802102282
– ident: CIT0084
  doi: 10.4103/2230-973X.119212
– ident: CIT0087
  doi: 10.1155/2017/7392891
– ident: CIT0240
  doi: 10.1369/0022155413503662
– ident: CIT0060
  doi: 10.1002/app.1978.070220417
– volume: 1
  start-page: 9
  year: 2014
  ident: CIT0004
  publication-title: Int. J. Sci. Res. Eng. Technol
– ident: CIT0285
  doi: 10.1080/10611860802095494
– ident: CIT0142
  doi: 10.1016/j.molmed.2012.04.012
– ident: CIT0260
  doi: 10.1007/s00280-008-0790-y
– ident: CIT0130
  doi: 10.1038/sj.neo.7900234
– ident: CIT0013
  doi: 10.3322/caac.21262
– ident: CIT0145
  doi: 10.1016/j.biomaterials.2012.09.044
– ident: CIT0157
  doi: 10.1038/sj.cgt.7700831
– ident: CIT0035
  doi: 10.1016/0955-2863(91)90019-2
– ident: CIT0238
  doi: 10.1016/j.ijpharm.2012.04.008
– volume: 60
  start-page: 2300
  year: 2000
  ident: CIT0116
  publication-title: Cancer Res
– ident: CIT0048
  doi: 10.1021/acsbiomaterials.6b00310
– ident: CIT0070
  doi: 10.1016/S0378-4347(97)00468-4">10.1016/S0378-4347(97)00468-4
– ident: CIT0246
  doi: 10.1016/j.actbio.2016.06.038">10.1016/j.actbio.2016.06.038
– ident: CIT0254
  doi: 10.1007/s11095-009-9929-8
– ident: CIT0066
  doi: 10.1016/j.polymer.2004.11.013
– ident: CIT0158
  doi: 10.1021/mp400644e
– ident: CIT0134
  doi: 10.3109/1061186X.2015.1070854
– ident: CIT0047
  doi: 10.1002/pat.1227
– ident: CIT0115
  doi: 10.1172/JCI200320337
– ident: CIT0271
  doi: 10.3892/or.2011.1243">10.3892/or.2011.1243
– ident: CIT0122
  doi: 10.1016/j.biomaterials.2003.09.087
– ident: CIT0131
  doi: 10.1038/srep02534
– ident: CIT0176
  doi: 10.3109/21691401.2015.1008510
– ident: CIT0256
  doi: 10.1021/bm050902y
– volume: 39
  start-page: 746
  year: 1993
  ident: CIT0046
  publication-title: Clin. Chem
  doi: 10.1093/clinchem/39.5.746
– ident: CIT0221
  doi: 10.1371/journal.pone.0069643">10.1371/journal.pone.0069643
– ident: CIT0190
  doi: 10.1002/jbm.a.34735
– ident: CIT0179
  doi: 10.1016/j.nano.2011.08.012
– ident: CIT0135
  doi: 10.1111/bph.12344
– ident: CIT0194
  doi: 10.1021/bc200139n
– ident: CIT0261
  doi: 10.1039/C4BM00272E
– ident: CIT0199
  doi: 10.1371/journal.pone.0024075">10.1371/journal.pone.0024075
– ident: CIT0180
  doi: 10.1002/app.32266">10.1002/app.32266
– ident: CIT0241
  doi: 10.1016/j.carbpol.2013.01.014
– ident: CIT0043
  doi: 10.1023/A:1020450326301
– ident: CIT0098
  doi: 10.1080/02652040400015346.
– ident: CIT0280
  doi: 10.1039/C5RA23067E
– ident: CIT0073
  doi: 10.1351/PAC-CON-11-10-19
– ident: CIT0002
  doi: 10.1016/j.ijpharm.2004.01.044
– ident: CIT0052
  doi: 10.1016/B978-0-12-396983-5.00009-0
– ident: CIT0074
  doi: 10.1039/C2DT30276D
– ident: CIT0149
  doi: 10.1021/mp500113p
– ident: CIT0187
  doi: 10.1166/jnn.2011.3102
– ident: CIT0025
  doi: 10.1016/j.ijpharm.2009.07.033
– ident: CIT0152
  doi: 10.2165/00126839-200708030-00001
– ident: CIT0072
  doi: 10.1007/978-3-642-19077-3_2
– ident: CIT0124
  doi: 10.1016/j.jconrel.2011.08.017
– ident: CIT0008
  doi: 10.1016/j.biomaterials.2004.09.052
– ident: CIT0081
  doi: 10.1002/ddr.10396
– ident: CIT0268
  doi: 10.1039/C4MD00348A
– ident: CIT0093
  doi: 10.1016/S0142-9612(00)00291-X
– ident: CIT0146
  doi: 10.1017/S1462399411001888">10.1017/S1462399411001888
– ident: CIT0210
  doi: 10.1186/1556-276X-8-66">10.1186/1556-276X-8-66
– start-page: 71
  volume-title: Biodegradable Polymers as Drug Delivery Systems
  year: 1990
  ident: CIT0029
– ident: CIT0167
  doi: 10.1007/s11095-007-9451-9
– ident: CIT0275
  doi: 10.2147/IJN.S76092">10.2147/IJN.S76092
– ident: CIT0107
  doi: 10.1016/j.colsurfb.2015.04.005
– ident: CIT0133
  doi: 10.1016/j.tranon.2015.12.005
– ident: CIT0068
  doi: 10.1021/bm0342382
– ident: CIT0171
  doi: 10.1593/tlo.10235
– ident: CIT0045
  doi: 10.1089/ten.tea.2008.0025
– ident: CIT0030
  doi: 10.1016/j.biomaterials.2005.09.019
– ident: CIT0100
  doi: 10.1163/156856297X00380
– ident: CIT0091
  doi: 10.1016/j.molliq.2018.02.024
– ident: CIT0102
  doi: 10.1088/1468-6996/13/3/035002">10.1088/1468-6996/13/3/035002
– ident: CIT0153
  doi: 10.1007/s11095-011-0440-7
– ident: CIT0212
  doi: 10.2147/IJN.S55541">10.2147/IJN.S55541
– ident: CIT0225
  doi: 10.1021/jp905781g
– ident: CIT0053
  doi: 10.1002/pat.733
– ident: CIT0076
  doi: 10.1002/masy.200650822">10.1002/masy.200650822
– ident: CIT0185
  doi: 10.1016/j.actbio.2009.11.035
– ident: CIT0044
  doi: 10.1016/S0141-3910(96)00208-X
– ident: CIT0162
  doi: 10.1002/ijc.29210
– ident: CIT0123
  doi: 10.1016/j.brainres.2008.01.039
– ident: CIT0126
  doi: 10.1016/j.ijpharm.2012.05.015
– ident: CIT0244
  doi: 10.1039/C5TB01939G
– ident: CIT0075
  doi: 10.1039/C7RA09038B
– ident: CIT0061
  doi: 10.1016/0032-3861(73)90017-7
– ident: CIT0168
  doi: 10.1016/j.ijpharm.2011.05.014
– ident: CIT0006
  doi: 10.1016/j.colsurfb.2009.09.001
– ident: CIT0161
  doi: 10.1016/j.ijpharm.2010.10.015
– ident: CIT0250
  doi: 10.1016/j.polymer.2008.06.005
– ident: CIT0230
  doi: 10.2147/IJN.S26401">10.2147/IJN.S26401
– ident: CIT0019
  doi: 10.1016/j.jconrel.2011.10.005
– ident: CIT0200
  doi: 10.1016/j.biomaterials.2014.04.099
– ident: CIT0164
  doi: 10.1016/j.lfs.2015.09.021
– ident: CIT0249
  doi: 10.2147/IJN.S78988">10.2147/IJN.S78988
– ident: CIT0139
  doi: 10.7150/thno.10257
– volume-title: CRC Handbook of Chemistry and Physics
  year: 2003
  ident: CIT0055
– ident: CIT0166
  doi: 10.1016/S0959-8049(01)00171-X
– ident: CIT0248
  doi: 10.2174/187152012800228788
– ident: CIT0024
  doi: 10.1016/j.ijpharm.2004.12.010
– volume: 5
  start-page: 577
  volume-title: Handbook of Nanostructured Materials and Nanotechnology: Organics, polymers, and biological materials
  year: 1999
  ident: CIT0016
– ident: CIT0054
  doi: 10.1016/j.ijpharm.2009.09.023
– ident: CIT0186
  doi: 10.1007/s10847-014-0422-6
– ident: CIT0011
  doi: 10.1166/jnn.2010.3617
– ident: CIT0022
  doi: 10.1016/j.nano.2005.12.003
– ident: CIT0058
  doi: 10.1039/B820162P
– ident: CIT0111
  doi: 10.1002/mnfr.200900277
– ident: CIT0172
  doi: 10.1016/j.canlet.2008.04.018
– ident: CIT0281
  doi: 10.1021/mp3000309
– ident: CIT0178
  doi: 10.1016/j.biopha.2016.10.095
– volume: 26
  start-page: 3595
  year: 2006
  ident: CIT0201
  publication-title: Anticancer Res
– ident: CIT0113
  doi: 10.1055/s-0042-112030
– ident: CIT0017
  doi: 10.1016/j.yexmp.2008.12.004
– ident: CIT0150
  doi: 10.1038/jcbfm.2013.41
– ident: CIT0218
  doi: 10.2147/IJN.S45250">10.2147/IJN.S45250
– ident: CIT0216
  doi: 10.1155/2017/9625909
– ident: CIT0189
  doi: 10.1166/jnn.2016.10739
– ident: CIT0236
  doi: 10.1016/j.jconrel.2009.11.002
– ident: CIT0259
  doi: 10.1158/1078-0432.CCR-07-4973
– ident: CIT0144
  doi: 10.1073/pnas.0408191101
– ident: CIT0014
  doi: 10.1158/1535-7163
– ident: CIT0208
  doi: 10.1038/aps.2016.20
– ident: CIT0182
  doi: 10.1016/S0169-409X(02)00047-9
– ident: CIT0132
  doi: 10.1016/j.jconrel.2013.10.002
– ident: CIT0020
  doi: 10.1155/2014/507273
– ident: CIT0196
  doi: 10.1016/j.colsurfb.2015.11.041
– ident: CIT0284
  doi: 10.1016/j.ijpharm.2013.07.069
– ident: CIT0033
  doi: 10.1093/nar/30.1.42
– ident: CIT0119
  doi: 10.2174/092986709788803312
– ident: CIT0204
  doi: 10.2147/IJN.S77667">10.2147/IJN.S77667
– ident: CIT0041
  doi: 10.1016/S0032-3861(99)00586-8
– ident: CIT0128
  doi: 10.1016/j.ejphar.2008.02.026
– ident: CIT0018
  doi: 10.1016/S0169-409X(02)00228-4
– volume: 23
  start-page: 21
  year: 2009
  ident: CIT0080
  publication-title: Trends Biomater. Artif. Organs
– ident: CIT0274
  doi: 10.1038/onc.2009.441
– ident: CIT0193
  doi: 10.1002/cbf.1149
– ident: CIT0270
  doi: 10.1371/journal.pone.0094309">10.1371/journal.pone.0094309
– ident: CIT0279
  doi: 10.1021/mp400342f
– ident: CIT0062
  doi: 10.1002/(SICI)1097-4628(19971031)66:5 < 921::AID-APP12 > 3.0.CO;2-Q
– ident: CIT0213
  doi: 10.7314/APJCP.2013.14.1.409
– ident: CIT0049
  doi: 10.1021/acs.biomac.6b01608
– ident: CIT0239
  doi: 10.1016/j.ejpb.2008.06.016
– ident: CIT0129
  doi: 10.1016/j.canlet.2009.02.018
– ident: CIT0088
  doi: 10.1016/j.msec.2015.08.058
– ident: CIT0276
  doi: 10.1039/C6RA03440C
– ident: CIT0050
  doi: 10.1039/C3RA42112K
– ident: CIT0227
  doi: 10.1039/c0nr00758g
– ident: CIT0247
  doi: 10.1016/j.polymer.2010.10.029
– ident: CIT0251
  doi: 10.1186/2162-3619-1-38">10.1186/2162-3619-1-38
– ident: CIT0252
  doi: 10.1016/j.actbio.2013.04.031
– ident: CIT0181
  doi: 10.4015/S1016237213400097">10.4015/S1016237213400097
– ident: CIT0211
  doi: 10.1080/21691401.2016.1203793
– ident: CIT0283
  doi: 10.1016/j.ejpb.2012.04.021
– ident: CIT0273
  doi: 10.1016/j.jconrel.2015.08.021
– ident: CIT0085
  doi: 10.5599/admet.3.2.167">10.5599/admet.3.2.167
– start-page: 79
  volume-title: Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties
  year: 2016
  ident: CIT0067
– ident: CIT0223
  doi: 10.1016/j.ejps.2015.10.021
– ident: CIT0243
  doi: 10.2147/IJN.S26697">10.2147/IJN.S26697
SSID ssj0013589
Score 2.496444
Snippet Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of...
SourceID crossref
informaworld
SourceType Enrichment Source
Index Database
Publisher
StartPage 85
SubjectTerms cancer
drug delivery systems
Nanomedicine
poly-ε-caprolactone
polymeric nanostructures
Title Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer
URI https://www.tandfonline.com/doi/abs/10.1080/00914037.2018.1539990
Volume 69
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9NAEF6FcgAOCAqI8tIeqAQKjuK3lxuNUlWIVpFIpdys3fW6sRTsKHEO9MKv4m_wczgz-7C9phXPSxI7WjvxfDs7szPzDUIvczIOGEwyh3jj3AmI7zpUCJhXUZy5eUBcpsIFp2fRyXnwfhEuBoPvVtbSrmYjfnltXcm_SBXOgVxllexfSLa9KJyAzyBfeAUJw-sfyXhWrT47h5Pp4VHocAq6cCW752izcTb5AF6-Ss6USVggTlV3DiM-iY1KLlwve9vZcgddF-PrQyuyLbcNjiu-U6GFkpZVE5GXuyVc4mZjG7n9XUaLm8LcveBDsJP1A2ot-u26KKtLZcqC_rooquFpcbETbQLIDK6nibfBFV8qhpBsQ9myQ_dHGXdSrAjmTW-OTzM5C6ou2LKlMjvgyKXb4azQnKQ6x5zrnLRmE8STuXSO17nM8yv9SGydT6SXrKllRsKo-ch3Qj9c2OuAbhlj8O5ZSl33FDLmgasL_K-sPE2qJpEEiLHMGUxGrqT91d1QfyL1Nt_cQDe9GGw-WXo0PuuiX2Gi3Tbzy5vKM8kJf90NejZVj3HXspXm99Bd4-Tgdxqx99FAlPvo1qTpLbiP7lg0mA_QF4Xjb197GMavAMGv32CKW_Rigx8Md8Z99GJAL-7Qi230vsUKu7gqsY1dXJRYY_chOj-ezicnjmkM4nDwRmonSQilEeUBI7mAVYWzAB6LiGIWujlLBA8493IeMlfS73l5JjIhWMbHBI5z3_Mfob0S_sljhBNY0UCJjYOMSc2UMwEqitGMgpIiMeEHKGgebcoNa75s3rJK3ZZcV0sklRJJjUQO0Kgdtta0Mb8bQGy5pbVCdK7BnPq_HPvkP8Y-Rbe7-fQM7dWbnXgOZnbNXihM_gBSI9ED
linkProvider Taylor & Francis
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV29TsMwELYQDMDATwFRfj0wgIRLnDhNzIYqqgKlYgCJLbIdWyBKWpV0gIWn4jV4Js51UwISMDAm8kW285195zt_h9Ce4R6ToGSE-54hjAeUCK1Br-pRSg3jVI7CBZedeuuGnd-Gt6W7MDat0vrQxhFFjNZqq9z2MLpIiTsCu8DSzEU2MyuuUUuuysFtnwnBHLdpfYHX-YwkhLEzgbn1lYKouMXz02e-7E9f2EtL-05zEamixy7d5KE2zGVNvXwjc_zfkJbQwtgsxScOR8toSmcVNNsoqsFV0HyJuHAFvV71us_k_Y0oAR3r2po9mcb7V432wSEWGN6BHLTEfWj3qAcYxof7d-Xjcwx9xe7yv3ssRdKPcbOnhk-4l-FMZL0i_o_vM6wsSger6KZ5et1okXEpB6LAfsxJHHMh6kIxyY2GdUBJ8CuprkcypEbGWjGlfKNCSS1hmm9SnWotUwXOJwtN4AdraDqDkawjHMMaBLDzWCotlozUACopUgGw4hFXVcSKH5ioMc-5LbfRTeiEDtXNdWLnOhnPdRXVJmJ9R_TxlwAvoyPJRycsxpVDSYJfZTf-IbuLZlvXl-2kfda52ERzvvX_PUp8fwtN54Oh3gYjKZc7Iy34AP7IBVo
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NThsxELYQlfg5tJBSQQvUBw4g1WG96_0xtyoQBQhRDkTitrK9tqiabqKwOZQLT8Vr8Ewdx7thgwQ9cNyVZ2V7v7FnPONvEDow3GMSlIxw3zOE8YASoTXoVRRn1DBO5SxccNWLOgN2cRNW2YR3ZVql9aGNI4qYrdVWuceZqTLijsEssCxzsU3MSprUcqty8No_RF7ALX1-4PWeAwlh4ixgbl2lIK4u8bz2mYXtaYG8tLbttD8hWXXYZZv8bk4L2VT3L7gc3zWiDfSxNErxT4eiTbSk8wZabVW14BpovUZb-Bk99EfDv-TpkSgB_Rraij25xof9VvfoBxYY3oEctMRjaPdHTzAMD49v64fnGLqK3dV_91iLo5_g9khN7_Aox7nIR1X0H__KsbIYnWyhQfvsutUhZSEHosB6LEiScCEioZjkRsMqoCR4lVRHsQypkYlWTCnfqFBSS5fmm0xnWstMgevJQhP4wRe0nMNIthFOYAUC0HkskxZJRmqAlBSZAFDxmKsdxKr_l6qS5dwW2ximdE6G6uY6tXOdlnO9g5pzsbGj-fifAK-DIy1m5yvGFUNJgzdlv75D9jta6Z-20-557_IbWvOt8-9R4vu7aLmYTPUeWEiF3J_pwD_aXAQH
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Poly-%CE%B5-caprolactone+%28PCL%29%2C+a+promising+polymer+for+pharmaceutical+and+biomedical+applications%3A+Focus+on+nanomedicine+in+cancer&rft.jtitle=International+journal+of+polymeric+materials&rft.au=Espinoza%2C+Sergio+Miguel&rft.au=Patil%2C+Harshal+Indrabhan&rft.au=San+Martin+Martinez%2C+Eduardo&rft.au=Casa%C3%B1as+Pimentel%2C+Rocio&rft.date=2020-01-22&rft.pub=Taylor+%26+Francis&rft.issn=0091-4037&rft.eissn=1563-535X&rft.volume=69&rft.issue=2&rft.spage=85&rft.epage=126&rft_id=info:doi/10.1080%2F00914037.2018.1539990&rft.externalDocID=1539990
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0091-4037&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0091-4037&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0091-4037&client=summon