Blockchain-based Clinical Trials: A Meta-Model Framework for Enhancing Security and Transparency with a Novel Algorithm

• Published in: International Journal of Technology Vol. 14; no. 6; pp. 1380 - 1392
• Main Authors: Anwar, Aymen, Goyal, S.B., Jan, Tony
• Format: Journal Article
• Language: English
• Published: Universitas Indonesia 31.10.2023
• Subjects: blockchain; clinical trials; data privacy; smart contracts; transparency
• ISSN: 2086-9614; 2087-2100; 2087-2100
• DOI: 10.14716/ijtech.v14i6.6703

Clinical trials are crucial to medication research, but data security, transparency, and integrity issues often arise. Blockchain technology offers a decentralized, tamper-proof framework for clinical trial data management, promising to overcome these issues. Current blockchain-based clinical trial platforms lack scalability, interoperability, and integrity. A meta-model paradigm for blockchain-based clinical trial security and transparency addresses these constraints. The system employs a unique algorithm with smart contracts and consensus procedures to protect data privacy, reduce redundancy, and promote platform compatibility. The algorithm aims to maximize resource consumption and reduce computational overhead while ensuring security and trust. To improve security and transparency, we analyze the proposed meta-model framework utilizing performance, scalability, and security metrics and benchmarks. We observed that the meta-model framework and algorithm are efficient, scalable, and safe, laying the groundwork for future research. In particular, the framework can minimize clinical trial costs and time while improving data quality, traceability, and accountability. The suggested meta-model framework and algorithm can improve blockchain-based clinical trial security and transparency, making data management more trustworthy and efficient.