A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI part 2: Validation using CT arthrography

• Published in: Magnetic resonance imaging Vol. 15; no. 7; pp. 805 - 813
• Main Authors: Haubner, Michael, Eckstein, Felix, Schnier, Michael, Lösch, Andreas, Sittek, Harald, Becker, Christoph, Kolem, Heiner, Reiser, Maximilian, Englmeier, Karl-Hans
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 1997; Elsevier Science
• Subjects: Adult; Arthrography - methods; Articular cartilage; Biological and medical sciences; Cadaver; Cartilage thickness; Cartilage, Articular - anatomy & histology; Cartilage, Articular - diagnostic imaging; CT arthrography; Humans; Image Processing, Computer-Assisted - methods; Investigative techniques, diagnostic techniques (general aspects); Knee Joint - anatomy & histology; Knee Joint - diagnostic imaging; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Medical sciences; Middle Aged; Osteoarticular system. Muscles; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Three-dimensional reconstruction; Tomography, X-Ray Computed - methods; Articular cartilage; Magnetic resonance imaging; Cartilage thickness; CT arthrography; Three-dimensional reconstruction; Thickness; Validation; Radiodiagnosis; Arthrography; Medical imagery; Tridimensional image; Computerized axial tomography; Technique; Nuclear magnetic resonance imaging; Image reconstruction
• ISSN: 0730-725X; 1873-5894
• DOI: 10.1016/S0730-725X(97)00011-8

Established methods for the measurement of articular cartilage thickness are invasive and cannot be sequentially applied in living subjects. In the present study, the distribution of cartilage thickness throughout entire joint surfaces was determined from MR images obtained with a fat-suppressed gradient-echo sequence at a resolution of 0.31 × 0.31 × 2.00 mm3, and compared to that derived from CT arthrography. A minimal distance algorithm was employed to produce 3D cartilage thickness maps of seven cadaveric human knee joints. The mean amount of deviation of the cartilage volumes was 5.6% (±4.6), statistical analysis showing that there was high agreement between the two methods (r = 0.995, slope = 1.037, y-intercept = -90.5 mm3). The 3D thickness maps yielded a striking agreement between the two methods, the maximum values generally yielding a deviation of none or one thickness interval of 0.5 mm. This investigation shows that accurate 3D assessment of articular cartilage thickness can be performed with MRI, this technique having the advantage that it is suitable for investigating living subjects.