Estimating the Variance of Estimator of the Latent Factor Linear Mixed Model Using Supplemented Expectation-Maximization Algorithm
This paper deals with symmetrical data that can be modelled based on Gaussian distribution, such as linear mixed models for longitudinal data. The latent factor linear mixed model (LFLMM) is a method generally used for analysing changes in high-dimensional longitudinal data. It is usual that the mod...
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          | Published in | Symmetry (Basel) Vol. 13; no. 7; p. 1286 | 
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| Main Authors | , , , , | 
| Format | Journal Article | 
| Language | English | 
| Published | 
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        01.07.2021
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| Online Access | Get full text | 
| ISSN | 2073-8994 2073-8994  | 
| DOI | 10.3390/sym13071286 | 
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| Abstract | This paper deals with symmetrical data that can be modelled based on Gaussian distribution, such as linear mixed models for longitudinal data. The latent factor linear mixed model (LFLMM) is a method generally used for analysing changes in high-dimensional longitudinal data. It is usual that the model estimates are based on the expectation-maximization (EM) algorithm, but unfortunately, the algorithm does not produce the standard errors of the regression coefficients, which then hampers testing procedures. To fill in the gap, the Supplemented EM (SEM) algorithm for the case of fixed variables is proposed in this paper. The computational aspects of the SEM algorithm have been investigated by means of simulation. We also calculate the variance matrix of beta using the second moment as a benchmark to compare with the asymptotic variance matrix of beta of SEM. Both the second moment and SEM produce symmetrical results, the variance estimates of beta are getting smaller when number of subjects in the simulation increases. In addition, the practical usefulness of this work was illustrated using real data on political attitudes and behaviour in Flanders-Belgium. | 
    
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| AbstractList | This paper deals with symmetrical data that can be modelled based on Gaussian distribution, such as linear mixed models for longitudinal data. The latent factor linear mixed model (LFLMM) is a method generally used for analysing changes in high-dimensional longitudinal data. It is usual that the model estimates are based on the expectation-maximization (EM) algorithm, but unfortunately, the algorithm does not produce the standard errors of the regression coefficients, which then hampers testing procedures. To fill in the gap, the Supplemented EM (SEM) algorithm for the case of fixed variables is proposed in this paper. The computational aspects of the SEM algorithm have been investigated by means of simulation. We also calculate the variance matrix of beta using the second moment as a benchmark to compare with the asymptotic variance matrix of beta of SEM. Both the second moment and SEM produce symmetrical results, the variance estimates of beta are getting smaller when number of subjects in the simulation increases. In addition, the practical usefulness of this work was illustrated using real data on political attitudes and behaviour in Flanders-Belgium. | 
    
| Author | Saefuddin, Asep Notodiputro, Khairil Anwar Toharudin, Toni Angraini, Yenni Folmer, Henk  | 
    
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| Copyright | 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. | 
    
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| References_xml | – ident: ref_10 doi: 10.3390/sym13040657 – volume: 86 start-page: 899 year: 1991 ident: ref_6 article-title: Using EM to Obtain Asymptotic Variance-Covariance Matrices: The SEM Algorithm publication-title: J. Am. Stat. Assoc. doi: 10.1080/01621459.1991.10475130 – volume: 44 start-page: 281 year: 2009 ident: ref_8 article-title: Covariance Structure Model Fit Testing Under Missing Data: An Application of the Supplemented EM Algorithm Covariance Structure Model Fit Testing Under Missing Data: An Application of the Supplemented EM Algorithm publication-title: Multivar. Behav. Res. doi: 10.1080/00273170902794255 – volume: 61 start-page: 309 year: 2008 ident: ref_7 article-title: SEM of another flavour: Two new applications of the supplemented EM algorithm publication-title: Br. J. Math. Stat. Psychol. doi: 10.1348/000711007X249603 – volume: 73 start-page: 412 year: 2012 ident: ref_9 article-title: Numerical Differentiation Methods for Computing Error Covariance Matrices in Item Response Theory Modeling: An Evaluation and a New Proposal publication-title: Educ. Psychol. Meas doi: 10.1177/0013164412465875 – volume: 34 start-page: 224 year: 1995 ident: ref_19 article-title: Church Involvement, Individualism, and Ethnic Prejudice among Flemish Roman Catholics: New Evidence of a Moderating Effect publication-title: J. Sci. Study Relig. doi: 10.2307/1386767 – volume: 81 start-page: 633 year: 1994 ident: ref_27 article-title: The ECME algorithm: A simple extension of EM and ECM with faster monotone convergence publication-title: Biometrika doi: 10.1093/biomet/81.4.633 – volume: 80 start-page: 267 year: 1993 ident: ref_24 article-title: Maximum likelihood estimation via the ECM algorithm: A general framework publication-title: Biometrika doi: 10.1093/biomet/80.2.267 – ident: ref_26 doi: 10.3390/sym12111877 – volume: 58 start-page: 590 year: 2015 ident: ref_2 article-title: Affective Properties of Mothers’ Speech to Infants with Hearing Impairment and Cochlear Implants publication-title: J. Speech Lang. Hear. Res. doi: 10.1044/2015_JSLHR-S-14-0095 – ident: ref_16 – volume: 85 start-page: 755 year: 1998 ident: ref_28 article-title: Parameter Expansion to Accelerate EM: The PX-EM Algorithm publication-title: Biometrika doi: 10.1093/biomet/85.4.755 – ident: ref_5 doi: 10.1002/9780470191613 – ident: ref_18 – volume: 49 start-page: 41 year: 2014 ident: ref_23 article-title: The Relationships between Individualism, Nationalism, Ethnocentrism, and Authoritarianism in Flanders: A Continuous Time-Structural Equation Modeling Approach publication-title: Multivar. Behav. Res. doi: 10.1080/00273171.2013.836621 – volume: 62 start-page: 83 year: 2008 ident: ref_21 article-title: Assessing the relationships between Nationalism, Ethnocentrism, and Individualism in Flanders using Bergstrom’s approximate discrete model publication-title: Stat. Neerl. doi: 10.1111/j.1467-9574.2007.00378.x – volume: 5 start-page: 55 year: 1995 ident: ref_25 article-title: Maximum Likelihood Estimation via the ECM Algorithm: Computing The Asymptotic Variance publication-title: Stat. Sin. – ident: ref_4 – ident: ref_14 doi: 10.1002/9781119013563 – volume: 32 start-page: 4229 year: 2013 ident: ref_1 article-title: A latent factor linear mixed model for high-dimensional longitudinal data analysis publication-title: Stat. Med. doi: 10.1002/sim.5825 – ident: ref_22 doi: 10.1007/978-3-531-18898-0 – volume: Volume 1 start-page: 697 year: 1972 ident: ref_12 article-title: A Missing Information Principle: Theory and Applications publication-title: Theory of Statistics doi: 10.1525/9780520325883-036 – ident: ref_15 – volume: 39 start-page: 1 year: 1977 ident: ref_13 article-title: Maximum Likelihood from Incomplete Data via the EM Algorithm A publication-title: J. R. Stat. Soc. Ser. B doi: 10.1111/j.2517-6161.1977.tb01600.x – volume: 36 start-page: 3244 year: 2017 ident: ref_3 article-title: Multidimensional latent trait linear mixed model: An application in clinical studies with multivariate longitudinal outcomes publication-title: Stat. Med. doi: 10.1002/sim.7347 – ident: ref_17 – volume: 4 start-page: 1 year: 2017 ident: ref_11 article-title: A comparison of parameter covariance estimation methods for item response models in an expectation-maximization framework publication-title: Cogent Psychol. doi: 10.1080/23311908.2017.1279435 – ident: ref_20  | 
    
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| SubjectTerms | Algorithms Dimensional changes Estimates Mathematical models Matrices (mathematics) Maximization Normal distribution Optimization Regression coefficients Simulation Statistical analysis Variables Variance  | 
    
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| Title | Estimating the Variance of Estimator of the Latent Factor Linear Mixed Model Using Supplemented Expectation-Maximization Algorithm | 
    
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