Upconversion nanoparticles: Recent strategies and mechanism based applications

Upconversion nanoparticles (UCNPs) doped with lanthanides can convert near-infrared excitation into UV and visible emissions. Because of their relatively high emission efficiency, UCNPs are appealing materials for use in a variety of sectors. UCNPs are known for low auto-fluorescence, excellent chem...

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Published inJournal of rare earths Vol. 40; no. 9; pp. 1343 - 1359
Main Authors Dubey, Neha, Chandra, Sudeshna
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.09.2022
Subjects
Applications
Luminescence
Mechanism
Optical imaging
Rare earths
Upconversion nanoparticles
Optical imaging
Applications
Rare earths
Mechanism
Luminescence
Upconversion nanoparticles
Online AccessGet full text
ISSN1002-0721
DOI10.1016/j.jre.2022.04.015

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Abstract Upconversion nanoparticles (UCNPs) doped with lanthanides can convert near-infrared excitation into UV and visible emissions. Because of their relatively high emission efficiency, UCNPs are appealing materials for use in a variety of sectors. UCNPs are known for low auto-fluorescence, excellent chemical and thermal photo-stability, deep tissue penetration, exceptional biocompatibility, low toxicity, color purity, and ease of surface functionalization. In this review, we explain a few recent strategies to boost the efficiency and luminescence of upconversion nanoparticles and minimize quenching by fabricating them as core/shell, nanofibers, or heavily doped lanthanides. Applications of UCNPs in drug delivery, Photodynamic therapy (PDT), biosensors, bioimaging, and optogenetics are also discussed along with their mechanism of action. Our motivation for this review is to understand the working mechanism of UCNPs and their applications in various fields. [Display omitted]
AbstractList Upconversion nanoparticles (UCNPs) doped with lanthanides can convert near-infrared excitation into UV and visible emissions. Because of their relatively high emission efficiency, UCNPs are appealing materials for use in a variety of sectors. UCNPs are known for low auto-fluorescence, excellent chemical and thermal photo-stability, deep tissue penetration, exceptional biocompatibility, low toxicity, color purity, and ease of surface functionalization. In this review, we explain a few recent strategies to boost the efficiency and luminescence of upconversion nanoparticles and minimize quenching by fabricating them as core/shell, nanofibers, or heavily doped lanthanides. Applications of UCNPs in drug delivery, Photodynamic therapy (PDT), biosensors, bioimaging, and optogenetics are also discussed along with their mechanism of action. Our motivation for this review is to understand the working mechanism of UCNPs and their applications in various fields. [Display omitted]
Author Dubey, Neha
Chandra, Sudeshna
Author_xml – sequence: 1
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  givenname: Sudeshna
  orcidid: 0000-0002-6565-9776
  surname: Chandra
  fullname: Chandra, Sudeshna
  email: sudeshna.chandra@nmims.edu, sudeshna.chandra@nmims.edu
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Snippet Upconversion nanoparticles (UCNPs) doped with lanthanides can convert near-infrared excitation into UV and visible emissions. Because of their relatively high...
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StartPage 1343
SubjectTerms Applications
Luminescence
Mechanism
Optical imaging
Rare earths
Upconversion nanoparticles
Title Upconversion nanoparticles: Recent strategies and mechanism based applications
URI https://dx.doi.org/10.1016/j.jre.2022.04.015
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