Advanced polymeric systems for colon drug delivery: from experimental models to market applications - Crispino, R; Lagreca, E; Procopio, A; D'Auria, R; Corrado, B; La Manna, S; Onesto, V; Di Natale, C (Soft matter, 2025)
Keywords: Administration, Oral; Animals; Bioavailability; Biocompatibility; Biodegradation; Cell Line, Tumor; Colitis, Ulcerative - drug therapy; Colon; Colon - drug effects; Colon cancer; Colonic Neoplasms - drug therapy; Colorectal carcinoma; Controlled release; Crohn's disease; Drug Carriers - chemistry; Drug delivery; Drug delivery systems; Drug Delivery Systems - instrumentation; Drug Delivery Systems - methods; Drug Industry; Drug Screening Assays, Antitumor; Gastrointestinal system; Gastrointestinal tract; Humans; Hydrogen-Ion Concentration; In vitro methods and tests; In vivo methods and tests; Inflammatory bowel diseases; Inflammatory Bowel Diseases - drug therapy; Intestine; Mathematical models; Mice; Microfluidics; Microparticles; Oral administration; Polymers; Polymers - chemistry; Sustained release; Time dependence; Toxicity; Transit time; Ulcerative colitis