Microsurgical free flaps for skull base reconstruction following tumor resection: Available techniques and complications
Resection of malignant tumors located in the anterior and middle fossae of the skull base requires thorough anatomical knowledge, as well as experience regarding the possible reconstructive options to resolve the resulting defects. The anatomical and functional relevance of the region, the complexit...
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Published in | Neurocirugía (Asturias, Spain) Vol. 34; no. 1; pp. 22 - 31 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier España, S.L.U
01.01.2023
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Subjects | |
Online Access | Get full text |
ISSN | 1130-1473 |
DOI | 10.1016/j.neucir.2021.12.002 |
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Abstract | Resection of malignant tumors located in the anterior and middle fossae of the skull base requires thorough anatomical knowledge, as well as experience regarding the possible reconstructive options to resolve the resulting defects. The anatomical and functional relevance of the region, the complexity of the defects requiring reconstruction and the potential complications that can occur, represent a true challenge for the surgical team. The goal of this study is to describe the microsurgical reconstructive techniques available, their usefulness and postoperative complications, in patients with malignant tumors involving the skull base.
This observational, retrospective study, included all patients who underwent surgery for malignant craniofacial tumors from January 1st, 2009 to January 1st, 2019 at a University Hospital in Argentina. Only patients who required reconstruction of the resulting defect with a free flap were included.
Twenty-four patients required reconstruction with FF; 14 were male (58.3%) and mean age was 54.9 years. Sarcoma was the most frequent tumor histology. Free flaps used were the following: anterolateral thigh, rectus abdominis, radial, latissimus dorsi, iliac crest and fibular. Complications occurred in 6 cases and no deaths were reported in the study group.
Free flaps are considered one of the preferable choices of treatment for large skull base defects. In spite of the complexity of the technique and the learning curve required, free flaps have shown to be safe, with a low rate of serious complications. For these patients, the surgical resolution should be performed by a multidisciplinary team.
La resección de los tumores malignos de la base de cráneo anterior y media requieren no solo un amplio conocimiento anatómico, sino también experiencia en las posibles opciones reconstructivas factibles para resolver el defecto generado. La importancia anatómica y funcional de la región, la complejidad de los defectos a reconstruir y las posibles complicaciones que pueden desarrollar representan un verdadero desafío para el equipo quirúrgico. El objetivo del presente trabajo es exponer las posibles opciones reconstructivas microquirúrgicas, su utilidad y las complicaciones postoperatorias en pacientes con tumores malignos que comprometen la base de cráneo.
Se realizó un estudio observacional retrospectivo de todos los pacientes operados de tumores malignos craneofaciales en el período comprendido entre el primero de enero de 2009 al primero de enero de 2019 en un hospital universitario de Argentina. Se incluyeron solo aquellos pacientes en los que fue necesario reconstruir el defecto a través de un colgajo libre (CL).
Veinticuatro pacientes requirieron reconstrucción con CL. Catorce fueron varones (n=14 [58,3%]) y la media de edad fue de 54,9 años. La variedad tumoral histológica más frecuente fue el sarcoma. Los tipos de CL utilizados fueron los siguientes: anterolateral de muslo, recto anterior del abdomen, radial, dorsal ancho, cresta iliaca y fibular fueron los CL utilizados. Se reportó una tasa global de complicaciones del n=6 (25%). Un solo paciente presentó isquemia del colgajo. No hubo mortalidad asociada.
Los CL representan una de las primeras opciones en el tratamiento en defectos grandes de la base de cráneo. A pesar de la complejidad de la técnica y la curva de aprendizaje necesaria, los CL han demostrado ser seguros con bajas tasas de complicaciones graves. La resolución quirúrgica de estos pacientes se debe realizar por un equipo multidisciplinario. |
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AbstractList | Resection of malignant tumors located in the anterior and middle fossae of the skull base requires thorough anatomical knowledge, as well as experience regarding the possible reconstructive options to resolve the resulting defects. The anatomical and functional relevance of the region, the complexity of the defects requiring reconstruction and the potential complications that can occur, represent a true challenge for the surgical team. The goal of this study is to describe the microsurgical reconstructive techniques available, their usefulness and postoperative complications, in patients with malignant tumors involving the skull base.
This observational, retrospective study, included all patients who underwent surgery for malignant craniofacial tumors from January 1st, 2009 to January 1st, 2019 at a University Hospital in Argentina. Only patients who required reconstruction of the resulting defect with a free flap were included.
Twenty-four patients required reconstruction with FF; 14 were male (58.3%) and mean age was 54.9 years. Sarcoma was the most frequent tumor histology. Free flaps used were the following: anterolateral thigh, rectus abdominis, radial, latissimus dorsi, iliac crest and fibular. Complications occurred in 6 cases and no deaths were reported in the study group.
Free flaps are considered one of the preferable choices of treatment for large skull base defects. In spite of the complexity of the technique and the learning curve required, free flaps have shown to be safe, with a low rate of serious complications. For these patients, the surgical resolution should be performed by a multidisciplinary team.
La resección de los tumores malignos de la base de cráneo anterior y media requieren no solo un amplio conocimiento anatómico, sino también experiencia en las posibles opciones reconstructivas factibles para resolver el defecto generado. La importancia anatómica y funcional de la región, la complejidad de los defectos a reconstruir y las posibles complicaciones que pueden desarrollar representan un verdadero desafío para el equipo quirúrgico. El objetivo del presente trabajo es exponer las posibles opciones reconstructivas microquirúrgicas, su utilidad y las complicaciones postoperatorias en pacientes con tumores malignos que comprometen la base de cráneo.
Se realizó un estudio observacional retrospectivo de todos los pacientes operados de tumores malignos craneofaciales en el período comprendido entre el primero de enero de 2009 al primero de enero de 2019 en un hospital universitario de Argentina. Se incluyeron solo aquellos pacientes en los que fue necesario reconstruir el defecto a través de un colgajo libre (CL).
Veinticuatro pacientes requirieron reconstrucción con CL. Catorce fueron varones (n=14 [58,3%]) y la media de edad fue de 54,9 años. La variedad tumoral histológica más frecuente fue el sarcoma. Los tipos de CL utilizados fueron los siguientes: anterolateral de muslo, recto anterior del abdomen, radial, dorsal ancho, cresta iliaca y fibular fueron los CL utilizados. Se reportó una tasa global de complicaciones del n=6 (25%). Un solo paciente presentó isquemia del colgajo. No hubo mortalidad asociada.
Los CL representan una de las primeras opciones en el tratamiento en defectos grandes de la base de cráneo. A pesar de la complejidad de la técnica y la curva de aprendizaje necesaria, los CL han demostrado ser seguros con bajas tasas de complicaciones graves. La resolución quirúrgica de estos pacientes se debe realizar por un equipo multidisciplinario. |
Author | Padilla-Lichtenberger, Fernando Ajler, Pablo Boccalatte, Luis Larrañaga, Juan Figari, Marcelo Plou, Pedro |
Author_xml | – sequence: 1 givenname: Pedro orcidid: 0000-0003-3435-6083 surname: Plou fullname: Plou, Pedro email: pedro.plou@hospitalitaliano.org.ar organization: Department of Neurosurgery, Hospital Italiano de Buenos Aires, Argentina – sequence: 2 givenname: Luis orcidid: 0000-0002-0096-418X surname: Boccalatte fullname: Boccalatte, Luis organization: Section of Head and Neck Surgery, Department of General Surgery, Hospital Italiano de Buenos Aires, Argentina – sequence: 3 givenname: Fernando orcidid: 0000-0002-4243-6705 surname: Padilla-Lichtenberger fullname: Padilla-Lichtenberger, Fernando organization: Department of Neurosurgery, Hospital Italiano de Buenos Aires, Argentina – sequence: 4 givenname: Marcelo surname: Figari fullname: Figari, Marcelo organization: Section of Head and Neck Surgery, Department of General Surgery, Hospital Italiano de Buenos Aires, Argentina – sequence: 5 givenname: Pablo surname: Ajler fullname: Ajler, Pablo organization: Department of Neurosurgery, Hospital Italiano de Buenos Aires, Argentina – sequence: 6 givenname: Juan surname: Larrañaga fullname: Larrañaga, Juan organization: Section of Head and Neck Surgery, Department of General Surgery, Hospital Italiano de Buenos Aires, Argentina |
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Cites_doi | 10.1001/archotol.128.2.161 10.1055/s-0039-1677881 10.1001/archotol.1993.01880240054007 10.1097/01.PRS.0000160691.63029.74 10.1016/j.bjps.2016.06.008 10.1055/s-0037-1606556 10.1097/PRS.0000000000003917 10.1177/014556131809700712 10.1055/s-0031-1286119 10.1097/00006534-199612000-00005 10.1097/00006534-199705010-00013 10.1002/hed.2880120502 10.1097/00006534-198606000-00005 10.1055/s-2006-932503 10.1055/s-0037-1607273 10.1002/cncr.25390 10.1001/archopht.1941.00870080015001 10.1055/s-0032-1329618 10.1016/S0094-1298(20)32722-X 10.1016/j.otohns.2009.02.025 10.1002/cncr.11630 10.1016/0002-9610(63)90387-8 10.1002/hed.2880160103 10.1001/archotol.1994.01880350017004 10.1097/SCS.0000000000000858 10.1001/archotol.125.3.295 10.1016/j.jcms.2016.10.017 10.1002/cncr.28108 10.1016/S0194-5998(99)70172-5 10.1002/(SICI)1097-0347(199901)21:1<12::AID-HED2>3.0.CO;2-# 10.1097/01.sap.0000218490.16921.c2 10.1002/(SICI)1097-0347(199609/10)18:5<412::AID-HED4>3.0.CO;2-8 10.1007/s10143-009-0222-4 10.1002/hed.20166 10.1002/hed.10147 10.1097/SAP.0b013e3181715707 10.1002/hed.2880160403 |
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Keywords | Cirugía de la base del cráneo Colgajo libre Malignant tumors Skull base surgery Free flap Tumores malignos Reconstrucción de la base del cráneo Skull base reconstruction |
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SubjectTerms | Cirugía de la base del cráneo Colgajo libre Free flap Malignant tumors Reconstrucción de la base del cráneo Skull base reconstruction Skull base surgery Tumores malignos |
Title | Microsurgical free flaps for skull base reconstruction following tumor resection: Available techniques and complications |
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