QRS duration and dispersion for predicting ventricular arrhythmias in early stage of acute myocardial infraction

To determine the relationship between QRS duration and dispersion and the occurrence of ventricular arrhythmias in early stages of acute myocardial infarction (AMI). A retrospective, longitudinal descriptive study was carried out. Hospital General Universitario “Camilo Cienfuegos”, Sancti Spíritus,...

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Published inMedicina intensiva (English ed.) Vol. 41; no. 6; pp. 347 - 355
Main Authors Chávez-González, E., Rodríguez Jiménez, A.E., Moreno-Martínez, F.L.
Format Journal Article
LanguageEnglish
Published Elsevier España, S.L.U 01.08.2017
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ISSN2173-5727
2173-5727
DOI10.1016/j.medine.2017.04.003

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Abstract To determine the relationship between QRS duration and dispersion and the occurrence of ventricular arrhythmias in early stages of acute myocardial infarction (AMI). A retrospective, longitudinal descriptive study was carried out. Hospital General Universitario “Camilo Cienfuegos”, Sancti Spíritus, Cuba. Secondary health care. A total of 209 patients diagnosed with ST-segment elevation AMI from January 2012 to June 2014. The duration and dispersion of the QT interval, corrected QT interval, and QRS complex were measured in the first electrocardiogram performed at the hospital. The presence of ventricular tachycardia/fibrillation was assessed during follow-up (length of hospital stay). Arrhythmias were found in 46 patients (22%); in 25 of them (15.9%), arrhythmias originated in ventricles, and were more common in those subjects with extensive anterior wall AMI, which was responsible for 81.8% of the ventricular fibrillations and more than half (57.1%) of the ventricular tachycardias. The widest QRS complexes (77.3±13.3 vs. 71.5±6.4ms; p=0.029) and their greatest dispersion (24.1±16.2 vs. 16.5±4.8ms; p=0.019) were found on those leads that explore the regions affected by ischaemia. The highest values of all measurements were found in extensive anterior wall AMI, with significant differences: QRS 92.3±18.8ms, QRS dispersion 37.9±23.9ms, corrected QT 518.5±72.2ms, and corrected QT interval dispersion 94.9±26.8ms. Patients with higher QRS dispersion values were more likely to have ventricular arrhythmias, with cutoff points at 23.5ms and 24.5ms for tachycardia and ventricular fibrillation, respectively. Increased QRS duration and dispersion implied a greater likelihood of ventricular arrhythmias in early stages of AMI than increased duration and dispersion of the corrected QT interval. Determinar la relación entre duración y dispersión del QRS con la aparición de arritmias ventriculares en las fases iniciales del infarto agudo de miocardio (IAM). Estudio descriptivo retrospectivo longitudinal. Hospital General Universitario «Camilo Cienfuegos» de Sancti Spíritus, Cuba. Atención secundaria. Doscientos nueve pacientes con diagnóstico de IAM con elevación del segmento ST entre enero de 2012 y junio de 2014. Se midieron la duración y dispersión del QT, QTc y QRS del primer electrocardiograma hospitalario y se determinó la presencia de taquicardia/fibrilación ventricular en el seguimiento (estancia hospitalaria). Se detectaron arritmias en 46 pacientes (22%), en 25 (15,9%) estas fueron ventriculares; más frecuentes en el IAM anterior extenso, que fue responsable del 81,8% de las fibrilaciones ventriculares y más de la mitad (57,1%) de las taquicardias ventriculares. La duración del QRS (77,3±13,3 vs. 71,5±6,4ms; p=0,029) y su dispersión (24,1±16,2 vs. 16,5±4,8ms; p=0,019) fue superior en las derivaciones afectadas por la isquemia. Los mayores valores de todas las mediciones se presentaron, con diferencia significativa, en el IAM anterior extenso: QRS 92,3±18,8ms, dQRS 37,9±23,9ms, QTc 518,5±72,2ms y dQTc 94,9±26,8ms. Los pacientes con mayores valores de dispersión del QRS tuvieron más probabilidad de presentar arritmias ventriculares, con puntos de corte de 23,5ms para la taquicardia y de 24,5ms para la fibrilación ventricular. El incremento de la duración y dispersión del QRS mostró mayor probabilidad de aparición de arritmias ventriculares en las fases iniciales del IAM que los incrementos del intervalo QTc y su dispersión.
AbstractList Abstract Objective To determine the relationship between QRS duration and dispersion and the occurrence of ventricular arrhythmias in early stages of acute myocardial infarction (AMI). Design A retrospective, longitudinal descriptive study was carried out. Setting Hospital General Universitario “Camilo Cienfuegos”, Sancti Spíritus, Cuba. Secondary health care. Patients or participants A total of 209 patients diagnosed with ST-segment elevation AMI from January 2012 to June 2014. Main variables of interest The duration and dispersion of the QT interval, corrected QT interval, and QRS complex were measured in the first electrocardiogram performed at the hospital. The presence of ventricular tachycardia/fibrillation was assessed during follow-up (length of hospital stay). Results Arrhythmias were found in 46 patients (22%); in 25 of them (15.9%), arrhythmias originated in ventricles, and were more common in those subjects with extensive anterior wall AMI, which was responsible for 81.8% of the ventricular fibrillations and more than half (57.1%) of the ventricular tachycardias. The widest QRS complexes (77.3 ± 13.3 vs. 71.5 ± 6.4 ms; p = 0.029) and their greatest dispersion (24.1 ± 16.2 vs. 16.5 ± 4.8 ms; p = 0.019) were found on those leads that explore the regions affected by ischaemia. The highest values of all measurements were found in extensive anterior wall AMI, with significant differences: QRS 92.3 ± 18.8 ms, QRS dispersion 37.9 ± 23.9 ms, corrected QT 518.5 ± 72.2 ms, and corrected QT interval dispersion 94.9 ± 26.8 ms. Patients with higher QRS dispersion values were more likely to have ventricular arrhythmias, with cutoff points at 23.5 ms and 24.5 ms for tachycardia and ventricular fibrillation, respectively. Conclusions Increased QRS duration and dispersion implied a greater likelihood of ventricular arrhythmias in early stages of AMI than increased duration and dispersion of the corrected QT interval.
To determine the relationship between QRS duration and dispersion and the occurrence of ventricular arrhythmias in early stages of acute myocardial infarction (AMI). A retrospective, longitudinal descriptive study was carried out. Hospital General Universitario “Camilo Cienfuegos”, Sancti Spíritus, Cuba. Secondary health care. A total of 209 patients diagnosed with ST-segment elevation AMI from January 2012 to June 2014. The duration and dispersion of the QT interval, corrected QT interval, and QRS complex were measured in the first electrocardiogram performed at the hospital. The presence of ventricular tachycardia/fibrillation was assessed during follow-up (length of hospital stay). Arrhythmias were found in 46 patients (22%); in 25 of them (15.9%), arrhythmias originated in ventricles, and were more common in those subjects with extensive anterior wall AMI, which was responsible for 81.8% of the ventricular fibrillations and more than half (57.1%) of the ventricular tachycardias. The widest QRS complexes (77.3±13.3 vs. 71.5±6.4ms; p=0.029) and their greatest dispersion (24.1±16.2 vs. 16.5±4.8ms; p=0.019) were found on those leads that explore the regions affected by ischaemia. The highest values of all measurements were found in extensive anterior wall AMI, with significant differences: QRS 92.3±18.8ms, QRS dispersion 37.9±23.9ms, corrected QT 518.5±72.2ms, and corrected QT interval dispersion 94.9±26.8ms. Patients with higher QRS dispersion values were more likely to have ventricular arrhythmias, with cutoff points at 23.5ms and 24.5ms for tachycardia and ventricular fibrillation, respectively. Increased QRS duration and dispersion implied a greater likelihood of ventricular arrhythmias in early stages of AMI than increased duration and dispersion of the corrected QT interval. Determinar la relación entre duración y dispersión del QRS con la aparición de arritmias ventriculares en las fases iniciales del infarto agudo de miocardio (IAM). Estudio descriptivo retrospectivo longitudinal. Hospital General Universitario «Camilo Cienfuegos» de Sancti Spíritus, Cuba. Atención secundaria. Doscientos nueve pacientes con diagnóstico de IAM con elevación del segmento ST entre enero de 2012 y junio de 2014. Se midieron la duración y dispersión del QT, QTc y QRS del primer electrocardiograma hospitalario y se determinó la presencia de taquicardia/fibrilación ventricular en el seguimiento (estancia hospitalaria). Se detectaron arritmias en 46 pacientes (22%), en 25 (15,9%) estas fueron ventriculares; más frecuentes en el IAM anterior extenso, que fue responsable del 81,8% de las fibrilaciones ventriculares y más de la mitad (57,1%) de las taquicardias ventriculares. La duración del QRS (77,3±13,3 vs. 71,5±6,4ms; p=0,029) y su dispersión (24,1±16,2 vs. 16,5±4,8ms; p=0,019) fue superior en las derivaciones afectadas por la isquemia. Los mayores valores de todas las mediciones se presentaron, con diferencia significativa, en el IAM anterior extenso: QRS 92,3±18,8ms, dQRS 37,9±23,9ms, QTc 518,5±72,2ms y dQTc 94,9±26,8ms. Los pacientes con mayores valores de dispersión del QRS tuvieron más probabilidad de presentar arritmias ventriculares, con puntos de corte de 23,5ms para la taquicardia y de 24,5ms para la fibrilación ventricular. El incremento de la duración y dispersión del QRS mostró mayor probabilidad de aparición de arritmias ventriculares en las fases iniciales del IAM que los incrementos del intervalo QTc y su dispersión.
Author Chávez-González, E.
Rodríguez Jiménez, A.E.
Moreno-Martínez, F.L.
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  surname: Rodríguez Jiménez
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CitedBy_id crossref_primary_10_1007_s12012_020_09599_x
crossref_primary_10_28982_josam_985876
crossref_primary_10_5798_dicletip_1500899
crossref_primary_10_17656_jsmc_10315
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Keywords Ventricular arrhythmias
QT interval
Síndrome coronario agudo
Duración del QRS
QRS duration
Acute coronary syndrome
Arritmias ventriculares
Predictores
Intervalo QT
QRS dispersion
Dispersión del QRS
Predictors
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Snippet To determine the relationship between QRS duration and dispersion and the occurrence of ventricular arrhythmias in early stages of acute myocardial infarction...
Abstract Objective To determine the relationship between QRS duration and dispersion and the occurrence of ventricular arrhythmias in early stages of acute...
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StartPage 347
SubjectTerms Acute coronary syndrome
Arritmias ventriculares
Critical Care
Dispersión del QRS
Duración del QRS
Internal Medicine
Intervalo QT
Predictores
Predictors
QRS dispersion
QRS duration
QT interval
Síndrome coronario agudo
Ventricular arrhythmias
Title QRS duration and dispersion for predicting ventricular arrhythmias in early stage of acute myocardial infraction
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