Cardiac Spindle Cell Sarcoma: A Challenging Presentation and Diagnosis of a Rare Malignant Primary Cardiac Tumor
We present a case of a 72‐year‐old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all left atria causing supravalvular obstruction. The magnetic resonance image revealed a 53 × 47 × 48 mm heterogeneous mass with regular edges,...
Saved in:
| Published in | Echocardiography (Mount Kisco, N.Y.) Vol. 42; no. 1; pp. e70070 - n/a |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.01.2025
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0742-2822 1540-8175 1540-8175 |
| DOI | 10.1111/echo.70070 |
Cover
| Abstract | We present a case of a 72‐year‐old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all left atria causing supravalvular obstruction. The magnetic resonance image revealed a 53 × 47 × 48 mm heterogeneous mass with regular edges, tissue characterization suggested myxoma. The patient underwent surgical resection, histopathologic study was compatible with sarcoma. This case underscores the importance of multimodal imaging for an accurate approach and early diagnosis of cardiac intracavitary masses. |
|---|---|
| AbstractList | We present a case of a 72-year-old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all left atria causing supravalvular obstruction. The magnetic resonance image revealed a 53 × 47 × 48 mm heterogeneous mass with regular edges, tissue characterization suggested myxoma. The patient underwent surgical resection, histopathologic study was compatible with sarcoma. This case underscores the importance of multimodal imaging for an accurate approach and early diagnosis of cardiac intracavitary masses.We present a case of a 72-year-old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all left atria causing supravalvular obstruction. The magnetic resonance image revealed a 53 × 47 × 48 mm heterogeneous mass with regular edges, tissue characterization suggested myxoma. The patient underwent surgical resection, histopathologic study was compatible with sarcoma. This case underscores the importance of multimodal imaging for an accurate approach and early diagnosis of cardiac intracavitary masses. We present a case of a 72‐year‐old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all left atria causing supravalvular obstruction. The magnetic resonance image revealed a 53 × 47 × 48 mm heterogeneous mass with regular edges, tissue characterization suggested myxoma. The patient underwent surgical resection, histopathologic study was compatible with sarcoma. This case underscores the importance of multimodal imaging for an accurate approach and early diagnosis of cardiac intracavitary masses. |
| Author | Meléndez‐Ramírez, Gabriela Pozas‐Rivas, Mario J. Posada‐Martínez, Edith L. Rodríguez‐Zanella, Hugo Sánchez‐Toscano, José A. Ortiz‐Leon, Xochitl A. Rodríguez‐Esparza, Jorge D. Fritche‐Salazar, Juan F. Arias‐Godínez, José A. |
| Author_xml | – sequence: 1 givenname: Jorge D. orcidid: 0009-0008-8431-8177 surname: Rodríguez‐Esparza fullname: Rodríguez‐Esparza, Jorge D. organization: National Institute of Cardiology Ignacio Chávez – sequence: 2 givenname: José A. orcidid: 0000-0002-5169-6007 surname: Sánchez‐Toscano fullname: Sánchez‐Toscano, José A. organization: National Institute of Cardiology Ignacio Chávez – sequence: 3 givenname: Gabriela orcidid: 0000-0001-7845-0974 surname: Meléndez‐Ramírez fullname: Meléndez‐Ramírez, Gabriela organization: National Institute of Cardiology Ignacio Chávez – sequence: 4 givenname: Juan F. orcidid: 0000-0002-3420-2861 surname: Fritche‐Salazar fullname: Fritche‐Salazar, Juan F. organization: National Institute of Cardiology Ignacio Chávez – sequence: 5 givenname: Hugo orcidid: 0000-0003-0336-5593 surname: Rodríguez‐Zanella fullname: Rodríguez‐Zanella, Hugo organization: National Institute of Cardiology Ignacio Chávez – sequence: 6 givenname: Edith L. orcidid: 0000-0002-3749-4281 surname: Posada‐Martínez fullname: Posada‐Martínez, Edith L. organization: National Institute of Cardiology Ignacio Chávez – sequence: 7 givenname: José A. orcidid: 0000-0002-7658-6146 surname: Arias‐Godínez fullname: Arias‐Godínez, José A. organization: National Institute of Cardiology Ignacio Chávez – sequence: 8 givenname: Mario J. surname: Pozas‐Rivas fullname: Pozas‐Rivas, Mario J. organization: National Institute of Cardiology Ignacio Chávez – sequence: 9 givenname: Xochitl A. orcidid: 0000-0001-7605-2008 surname: Ortiz‐Leon fullname: Ortiz‐Leon, Xochitl A. email: xochitlortiz6@gmail.com organization: National Institute of Cardiology Ignacio Chávez |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39737702$$D View this record in MEDLINE/PubMed |
| BookMark | eNp90U1P4zAQBmALgaAULvyAlY8IKeCPpHa5ocBuVwKB-DhHE3tcvErsYrdC_HvCBjgyF1-eGY_97pPtEAMScsTZKR_qDM1zPFWMKbZFJrwqWaG5qrbJhKlSFEILsUf2c_7HBsJ5uUv25FxJpZiYkFUNyXow9GHlg-2Q1th19AGSiT2c0wtaP0PXYVj6sKR3CTOGNax9DBSCpZceliFmn2l0FOg9JKQ30PllgLAeuO8hvdGvKx43fUwHZMdBl_Hw85ySp99Xj_WiuL7987e-uC6M0JoVrTbatMjVXDPmnFR6brFshbSSzyqlgekKpWutLufWzJQrhbOqNaWruDQg5ZQcj3NXKb5sMK-b3mczPA4Cxk1uJK-YLCs1EwP99Uk3bY-2WY17N1-_NICTEZgUc07ovglnzUcEzUcEzf8IBsxH_Oo7fPtBNlf14nbseQfOuYfC |
| Cites_doi | 10.1016/j.jaccao.2020.05.009 10.1097/JTO.0b013e3181e59a91 10.1016/j.radcr.2023.11.065 10.1161/CIRCIMAGING.123.016115 |
| ContentType | Journal Article |
| Copyright | 2024 Wiley Periodicals LLC. |
| Copyright_xml | – notice: 2024 Wiley Periodicals LLC. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1111/echo.70070 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1540-8175 |
| EndPage | n/a |
| ExternalDocumentID | 39737702 10_1111_echo_70070 ECHO70070 |
| Genre | caseStudy Journal Article Case Reports |
| GroupedDBID | --- .3N .GA .GJ .Y3 04C 05W 0R~ 10A 1OB 1OC 29G 31~ 33P 36B 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5RE 5VS 66C 6PF 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAESR AAEVG AAHHS AAHQN AAIPD AAMNL AANHP AANLZ AAONW AASGY AAWTL AAXRX AAYCA AAZKR ABCQN ABCUV ABDBF ABEML ABJNI ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACGFS ACGOF ACMXC ACPOU ACRPL ACSCC ACUHS ACXBN ACXQS ACYXJ ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADNMO ADOJX ADOZA ADXAS ADZMN ADZOD AEEZP AEGXH AEIGN AEIMD AEQDE AEUQT AEUYR AFBPY AFEBI AFFPM AFGKR AFPWT AFWVQ AFZJQ AHBTC AHEFC AIACR AITYG AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMSDO BMXJE BPMNR BROTX BRXPI BY8 C45 CAG COF CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM EAD EAP EAS EBC EBD EBS ECF ECT ECV EIHBH EJD EMB EMK EMOBN ENC EPT ESX EX3 F00 F01 F04 F5P FEDTE FUBAC FZ0 G-S G.N GODZA H.X HF~ HGLYW HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OIG OVD P2W P2X P2Z P4B P4D PALCI Q.N Q11 QB0 Q~Q R.K RIWAO RJQFR ROL RX1 SAMSI SUPJJ SV3 TEORI TUS UB1 V8K V9Y W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQ9 WQJ WRC WUP WVDHM WXI WXSBR XG1 ZGI ZZTAW ~IA ~WT AAYXX AEYWJ AGHNM AGQPQ AGYGG CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| ID | FETCH-LOGICAL-c2880-b8c8cbe179800ff3789de4b23d316578a085e3fbd849dc67f42fd7bc4f513ca33 |
| IEDL.DBID | DR2 |
| ISSN | 0742-2822 1540-8175 |
| IngestDate | Thu Sep 04 21:15:47 EDT 2025 Wed Feb 19 01:58:22 EST 2025 Tue Jul 01 03:39:34 EDT 2025 Wed Jan 29 10:50:39 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | left atrial mass cardiac sarcoma transesophageal echocardiography multimodal cardiac imaging supravalvular mitral stenosis |
| Language | English |
| License | 2024 Wiley Periodicals LLC. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c2880-b8c8cbe179800ff3789de4b23d316578a085e3fbd849dc67f42fd7bc4f513ca33 |
| Notes | The authors received no specific funding for this work. Funding ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 |
| ORCID | 0000-0002-7658-6146 0000-0003-0336-5593 0000-0001-7845-0974 0000-0002-3749-4281 0009-0008-8431-8177 0000-0002-5169-6007 0000-0001-7605-2008 0000-0002-3420-2861 |
| PMID | 39737702 |
| PQID | 3150345762 |
| PQPubID | 23479 |
| PageCount | 3 |
| ParticipantIDs | proquest_miscellaneous_3150345762 pubmed_primary_39737702 crossref_primary_10_1111_echo_70070 wiley_primary_10_1111_echo_70070_ECHO70070 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | January 2025 2025-01-00 2025-Jan 20250101 |
| PublicationDateYYYYMMDD | 2025-01-01 |
| PublicationDate_xml | – month: 01 year: 2025 text: January 2025 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Echocardiography (Mount Kisco, N.Y.) |
| PublicationTitleAlternate | Echocardiography |
| PublicationYear | 2025 |
| References | 2010; 5 2020; 5 2024; 17 2020; 2 2023; 19 e_1_2_6_3_1 e_1_2_6_2_1 e_1_2_6_4_1 e_1_2_6_6_1 Todd Prol D. O. (e_1_2_6_5_1) 2020; 5 |
| References_xml | – volume: 5 start-page: 1483 issue: 9 year: 2010 end-page: 1489 article-title: Cardiac Sarcomas: An Update publication-title: Journal of Thoracic Oncology – volume: 5 start-page: 56 issue: 1 year: 2020 article-title: Primary Cardiac Sarcoma Involving the Mitral Valve, an Insidious Form of Heart Failure publication-title: CASE (Phila) – volume: 2 start-page: 293 issue: 2 year: 2020 end-page: 311 article-title: Cardiac Tumors: JACC CardioOncology State‐of‐the‐Art Review publication-title: JACC: CardioOncology – volume: 17 issue: 3 year: 2024 article-title: Cardiac Magnetic Resonance to Predict Cardiac Mass Malignancy: The CMR Mass Score publication-title: Circulation: Cardiovascular Imaging – volume: 19 start-page: 1200 issue: 3 year: 2023 end-page: 1207 article-title: Clinical Presentation, Diagnostic Evaluation, and Management of Undifferentiated/Unclassified Cardiac Sarcoma: A Case Report and Literature Review publication-title: Radiology Case Reports – ident: e_1_2_6_3_1 doi: 10.1016/j.jaccao.2020.05.009 – volume: 5 start-page: 56 issue: 1 year: 2020 ident: e_1_2_6_5_1 article-title: Primary Cardiac Sarcoma Involving the Mitral Valve, an Insidious Form of Heart Failure publication-title: CASE (Phila) – ident: e_1_2_6_2_1 doi: 10.1097/JTO.0b013e3181e59a91 – ident: e_1_2_6_4_1 doi: 10.1016/j.radcr.2023.11.065 – ident: e_1_2_6_6_1 doi: 10.1161/CIRCIMAGING.123.016115 |
| SSID | ssj0007114 |
| Score | 2.3822687 |
| Snippet | We present a case of a 72‐year‐old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all... We present a case of a 72-year-old female patient with dyspnea and lipothymia. Echocardiography demonstrates an intracavitary cystic mass that fills almost all... |
| SourceID | proquest pubmed crossref wiley |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | e70070 |
| SubjectTerms | Aged cardiac sarcoma Diagnosis, Differential Echocardiography - methods Female Heart Atria - diagnostic imaging Heart Neoplasms - diagnosis Heart Neoplasms - diagnostic imaging Heart Neoplasms - surgery Humans left atrial mass Magnetic Resonance Imaging - methods multimodal cardiac imaging Rare Diseases Sarcoma - diagnosis Sarcoma - diagnostic imaging Sarcoma - surgery supravalvular mitral stenosis transesophageal echocardiography |
| Title | Cardiac Spindle Cell Sarcoma: A Challenging Presentation and Diagnosis of a Rare Malignant Primary Cardiac Tumor |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fecho.70070 https://www.ncbi.nlm.nih.gov/pubmed/39737702 https://www.proquest.com/docview/3150345762 |
| Volume | 42 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bS-UwEA7iw-KLuquuR3cl4j4JPbRNTpMu-yJVEeGIeAFflpLLRERtD-fy4q93krYe3QVB3wq9JM1kZr5JJt8Q8otBil7eiMiZ2AcolkdK5lkklWbSZSBsqEM2PMtOrvnpzeBmgfzpzsI0_BAvC25eM4K99gqu9OSVkgOah77wdDVogBOWeeL8w4s5d5RIGmJv4c-foBtsuUl9Gs_81bfe6D-I-RaxBpdzvEL-dp1tMk3u-7Op7punf3gcP_s3q2S5xaL0oJk8X8kCVN_Il2G7275GRkWYPoZeju48FwMt4OGBXqJq1I_qNz2gRVuJBd0fPZ-fY6qoqiw9bJL47ia0dlTRCzUGOkTUf-tTb_DxwHJBuyauZo_1eJ1cHx9dFSdRW6EhMikqfqSlkUaDJz2LY-eYkLkFrlNmWZKhLVAI6IA5bSXPrcmE46mzQhvuBgkzirENsljVFWwSaiExCXCu5QBBkpN5kosBaM4AZRdD0iN7naTKUdPFsgtg_OCVYfB6ZLcTYol64jc_VAX1bFIyRL6MY3SV9sj3Rrov30FMxoSI8c5-kNE7DZRHBQb8_mrrIw9vk6XUFw4Oazc_yOJ0PIOfiGameifM2mcTee6R |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELagSMCFd2F5GsEJKask9sYOtypttUC3Qu1W6i3yY4wq2mS1j0t_fWecbJeChAS3SHHixOPxfDMef8PYRwE5WnmnkuBSclC8TIwui0QbK3QoQPlYh2xyWIxP5NfT0Wmfm0NnYTp-iOuAG2lGXK9JwSkg_YuWA64PQ0V8NbfZHYlIg3yv3aMNe5TKOmpvRSdQ0BD27KSUyLN59qY9-gNk3sSs0ejsP-wqqy4iVyHlmvwcrpZ26C5_Y3L87_95xB70cJTvdPPnMbsFzRN2d9JvuD9lsyrOIMePZ2dEx8ArOD_nx6gd7YX5zHd41RdjQQvIv2-OMjXcNJ7vdnl8ZwveBm74kZkDnyDw_0HZN9g8El3wdRfT1UU7f8ZO9vem1TjpizQkLkfdT6x22lkg3rM0DUEoXXqQNhdeZAUuBwYxHYhgvZald4UKMg9eWSfDKBPOCLHNtpq2gReMe8hcBlJaPUKcFHSZlWoEVgpA4aWQDdiHtajqWfeJ9dqHocGr4-AN2Pu1FGtUFdr_MA20q0UtEPwKiQ5WPmDPO_FevwdhmVAqxTufopD-0kG9V6HPT1cv_6XxO3ZvPJ0c1AdfDr-9YvdzqiMcQzmv2dZyvoI3CG6W9m2cwlcJrPKw |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Za9wwEB7SFEJfeh_bU6V9KnixLa0ll74EJ0t6bAg5IC_F6BiV0MReNrsv_fUdyXa2aaHQvhksW8doNN9Io28A3nLMycpbmXibBgfFiUSrskiUNlz5AqWLechm-8Xeifh0OjndgA_DXZiOH-Jqwy1oRlyvg4LPnf9FyZGWh7EMdDU34KYoCEoESHS4Jo-SWcfsLcMFFLKDPTlpiONZf3vdHP2BMa9D1mhzpnfg69DaLtTk-3i1NGP74zcix__tzl243YNRtt3Nnnuwgc192Jr1x-0PYF7F-WPZ0fwskDGwCs_P2RHpRnuh37NtVvWpWMj-sYP1RaaG6caxnS6K7-yStZ5pdqgXyGYE-7-F2BsqHmku2FDF8eqiXTyEk-nucbWX9CkaEpuT5idGWWUNBtazNPWeS1U6FCbnjmcFLQaaEB1yb5wSpbOF9CL3Thor_CTjVnP-CDabtsEnwBxmNkMhjJoQSvKqzEo5QSM4kuxSzEbwZpBUPe-aWA8eTBi8Og7eCF4PQqxJUcLph26wXV3WnKAvF-Re5SN43En36j8EyriUKb15F2X0lwrq3Yo8_vD09F8Kv4Ktg51p_eXj_udncCsPSYTjPs5z2FwuVviCkM3SvIwT-Cc--_Ff |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cardiac+Spindle+Cell+Sarcoma%3A+A+Challenging+Presentation+and+Diagnosis+of+a+Rare+Malignant+Primary+Cardiac+Tumor&rft.jtitle=Echocardiography+%28Mount+Kisco%2C+N.Y.%29&rft.au=Rodr%C3%ADguez%E2%80%90Esparza%2C+Jorge+D.&rft.au=S%C3%A1nchez%E2%80%90Toscano%2C+Jos%C3%A9+A.&rft.au=Mel%C3%A9ndez%E2%80%90Ram%C3%ADrez%2C+Gabriela&rft.au=Fritche%E2%80%90Salazar%2C+Juan+F.&rft.date=2025-01-01&rft.issn=0742-2822&rft.eissn=1540-8175&rft.volume=42&rft.issue=1&rft_id=info:doi/10.1111%2Fecho.70070&rft.externalDBID=n%2Fa&rft.externalDocID=10_1111_echo_70070 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0742-2822&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0742-2822&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0742-2822&client=summon |