Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds - Griswold, Anthony J.; Celis, Katrina; Bussies, Parker L.; Rajabli, Farid; Whitehead, Patrice L.; Hamilton‐Nelson, Kara L.; Beecham, Gary W.; Dykxhoorn, Derek M.; Nuytemans, Karen; Wang, Liyong; Gardner, Olivia K.; Dorfsman, Daniel A.; et al. (Alzheimer's & dementia, 2021)
Keywords: Aged; Aged, 80 and over; Alleles; Alzheimer Disease - ethnology; Alzheimer Disease - genetics; Alzheimer's disease; APOE; Apolipoprotein E4 - genetics; Black People - genetics; Female; Heterozygote; Humans; local ancestry; Male; Sequence Analysis, RNA; single‐nucleus RNA‐seq; White People - genetics; APOE; single-nucleus RNA-seq; local ancestry; Alzheimer's disease