What is Cardiometabolic HFpEF and How Can We Study it Preclinically? - Daou, Daniel, MD; Tong, Dan, MD, PhD; Schiattarella, Gabriele G., MD, PhD; Gillette, Thomas G., PhD; Hill, Joseph A., MD, PhD (JACC. Basic to translational science, 2025)
Keywords: Cardiovascular; db/db; eNOS; surgical aortic banding; ejection fraction; TTE; ob/ob; HFD; HFpEF; cardiometabolic; HFrEF; WD; GLS; inducible nitric oxide synthase; heart failure with preserved ejection fraction; endothelial nitric oxide synthase; iNOS; N ω-nitro-L-arginine methyl ester; heart failure with reduced ejection fraction; AB; EF; Maximal oxygen uptake; preclinical models; L-NAME; transthoracic echocardiography; leptin receptor-deficient mice; Ang II; global longitudinal strain; angiotensin II; high-fat diet; leptin-deficient mice; EAT; epicardial adipose tissue; VO 2max; Western diet