The Evolution of Virtual Physiologic Assessments and Virtual Coronary Intervention to Optimize Revascularization

Purpose of Review In this review, we summarize the use of virtual physiologic functional assessments of coronary artery disease and their utility to guide virtual coronary intervention (VCI). Recent Findings Virtual fractional flow reserve (vFFR), coronary angiography–derived fractional flow reserve...

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Published inCurrent cardiovascular imaging reports Vol. 14; no. 4
Main Authors Stout, Kara M., Boudoulas, Kostantinos D., Povsic, Thomas J., Altin, S. Elissa, Jhand, Aravdeep S., Bailey, Steven R., Goldsweig, Andrew M.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.04.2021
Springer Nature B.V
Subjects
Angiography
Assessments
Cardiology
Cardiovascular disease
Coronary artery disease
Decision making
Diagnostic Radiology
Imaging
Interventional Radiology
Intravascular Imaging (A.G. Truesdell
Medicine
Medicine & Public Health
Nuclear Medicine
Pressure ratio
Radiology
Section Editor
Topical Collection on Intravascular Imaging
Ultrasound
Wire
coronary angiography–derived fractional flow reserve
Virtual physiologic assessment
VCI (virtual coronary intervention)
FFR
cFFR (virtual contrast FFR)
vFFR (virtual fractional flow reserve)
QFR (quantitative flow reserve)
Online AccessGet full text
ISSN1941-9066
1941-9074
DOI10.1007/s12410-021-09554-6

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Abstract Purpose of Review In this review, we summarize the use of virtual physiologic functional assessments of coronary artery disease and their utility to guide virtual coronary intervention (VCI). Recent Findings Virtual fractional flow reserve (vFFR), coronary angiography–derived fractional flow reserve (FFR angio ), virtual contrast FFR (cFFR), and quantitative flow reserve (QFR) are four technologies that generate computer-based FFR measurements comparable to the gold standard of pressure-wire-based FFR. VCI capitalizes on this technology by utilizing pre- and post-vFFR assessments to predict the physiologic response to stenting. Summary Physiologic assessment of coronary lesion significance has become a cornerstone of decision-making for revascularization. FFR and non-hyperemic pressure ratio use is limited by the requirement for an intracoronary wire and the additional time required. Virtual physiologic assessments address these shortcomings with accuracy comparable to FFR. Building on this technology, VCI simulation has the potential to revolutionize the approach to percutaneous revascularization.
AbstractList Purpose of ReviewIn this review, we summarize the use of virtual physiologic functional assessments of coronary artery disease and their utility to guide virtual coronary intervention (VCI).Recent FindingsVirtual fractional flow reserve (vFFR), coronary angiography–derived fractional flow reserve (FFRangio), virtual contrast FFR (cFFR), and quantitative flow reserve (QFR) are four technologies that generate computer-based FFR measurements comparable to the gold standard of pressure-wire-based FFR. VCI capitalizes on this technology by utilizing pre- and post-vFFR assessments to predict the physiologic response to stenting.SummaryPhysiologic assessment of coronary lesion significance has become a cornerstone of decision-making for revascularization. FFR and non-hyperemic pressure ratio use is limited by the requirement for an intracoronary wire and the additional time required. Virtual physiologic assessments address these shortcomings with accuracy comparable to FFR. Building on this technology, VCI simulation has the potential to revolutionize the approach to percutaneous revascularization.
Purpose of Review In this review, we summarize the use of virtual physiologic functional assessments of coronary artery disease and their utility to guide virtual coronary intervention (VCI). Recent Findings Virtual fractional flow reserve (vFFR), coronary angiography–derived fractional flow reserve (FFR angio ), virtual contrast FFR (cFFR), and quantitative flow reserve (QFR) are four technologies that generate computer-based FFR measurements comparable to the gold standard of pressure-wire-based FFR. VCI capitalizes on this technology by utilizing pre- and post-vFFR assessments to predict the physiologic response to stenting. Summary Physiologic assessment of coronary lesion significance has become a cornerstone of decision-making for revascularization. FFR and non-hyperemic pressure ratio use is limited by the requirement for an intracoronary wire and the additional time required. Virtual physiologic assessments address these shortcomings with accuracy comparable to FFR. Building on this technology, VCI simulation has the potential to revolutionize the approach to percutaneous revascularization.
ArticleNumber 4
Author Goldsweig, Andrew M.
Povsic, Thomas J.
Boudoulas, Kostantinos D.
Bailey, Steven R.
Altin, S. Elissa
Stout, Kara M.
Jhand, Aravdeep S.
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  organization: Division of Cardiovascular Medicine, University of Nebraska Medical Center
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Cites_doi 10.1016/0002-8703(52)90210-x
10.1016/j.jacc.2017.07.770
10.1016/j.jacc.2013.09.060
10.1161/01.cir.0000020547.92091.76
10.1016/j.amjcard.2014.07.013
10.1016/j.jcin.2016.12.015
10.1136/hrt.2006.100818
10.1016/j.jcin.2020.04.040
10.1161/CIRCINTERVENTIONS.118.007494
10.1016/j.jacc.2017.10.035
10.4244/EIJY14M08_17
10.1093/eurheartj/ehi484
10.1136/heartjnl-2015-308044
10.1161/CIRCINTERVENTIONS.119.008263
10.1155/2020/3942152
10.1016/j.jacc.2017.04.019
10.1007/s11936-020-0803-7
10.1093/eurheartj/ehv452
10.1161/CIRCIMAGING.117.007107
10.1016/j.jcin.2018.04.037
10.1016/j.jcin.2016.07.013
10.1016/j.jcin.2016.01.046
10.1161/CIRCULATIONAHA.118.037350
10.1161/01.cir.87.4.1354
10.1161/JAHA.118.009603
10.1016/j.jacc.2018.09.042
10.1016/j.hlc.2018.02.011
10.1016/j.jcin.2012.08.024
10.1161/01.CIR.0000074211.28917.31
10.1056/NEJMoa1205361
10.4244/EIJV9I1A14
10.4244/EIJY19M01_01
10.1093/eurheartj/ehy632
10.1016/j.jacc.2017.02.001
10.4244/EIJY14M07_01
10.1056/NEJMoa1700445
10.1161/CIRCULATIONAHA.118.037528
10.1056/NEJMoa0807611
10.1016/j.jcin.2015.04.006
10.1016/j.jcin.2019.05.054
10.1056/NEJM199606273342604
10.1002/clc.4960140106
10.1016/j.jcmg.2018.01.019
10.1016/j.ijcard.2018.07.029
10.1161/CIRCULATIONAHA.115.018747
10.4244/EIJ-D-19-00466
10.1016/j.jacc.2012.11.083
10.1007/s00330-018-5781-8
10.1016/j.amjcard.2011.02.329
10.1016/j.jacbts.2017.04.003
10.1001/jama.293.23.2908
10.1056/NEJMoa1915922
10.1016/j.jacc.2011.11.003
10.1161/CIR.0b013e31823ba622
10.1056/NEJMoa1616540
10.1161/CIRCULATIONAHA.118.037021
10.1002/ccd.29558
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Keywords coronary angiography–derived fractional flow reserve
Virtual physiologic assessment
VCI (virtual coronary intervention)
FFR
cFFR (virtual contrast FFR)
vFFR (virtual fractional flow reserve)
QFR (quantitative flow reserve)
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References Chahour, Aboulaich, Habbal, Zemzemi, Abdelkhirane (CR35) 2020; 2020
Xu, Tu, Qiao, Qu, Chen, Yang, Guo, Sun, Li, Tian, Fang, Chen, Li, Guan, Holm, Wijns, Hu (CR50) 2017; 70
Pijls, van Son, Kirkeeide, De Bruyne, Gould (CR9) 1993; 87
Davies, Sen, Dehbi, Al-Lamee, Petraco, Nijjer (CR25) 2017; 376
Morris, Ryan, Morton, Lycett, Lawford, Hose, Gunn (CR38) 2013; 6
Maron, Hochman, Reynolds, Bangalore, O ' Brien, Boden, Chaitman, Senior, López-Sendón, Alexander, Lopes, Shaw, Berger, Newman, Sidhu, Goodman, Ruzyllo, Gosselin, Maggioni, White, Bhargava, Min, Mancini, Berman, Picard, Kwong, Ali, Mark, Spertus, Krishnan, Elghamaz, Moorthy, Hueb, Demkow, Mavromatis, Bockeria, Peteiro, Miller, Szwed, Doerr, Keltai, Selvanayagam, Steg, Held, Kohsaka, Mavromichalis, Kirby, Jeffries, Harrell FE Jr, Rockhold, Broderick, Ferguson TB Jr, Williams, Harrington, Stone, Rosenberg (CR4) 2020; 382
Adjedj, De Bruyne, Flore, Di Gioia, Ferrara, Pellicano (CR14) 2016; 133
Gosling, Morris, Silva Soto, Lawford, Hose, Gunn (CR55) 2019; 12
Zimmermann, Ferrara, Johnson, van Nunen, Escaned, Albertsson, Erbel, Legrand, Gwon, Remkes, Stella, van Schaardenburgh, Bech, de Bruyne, Pijls (CR12) 2015; 36
Fearon, Achenbach, Engstrom, Assali, Shlofmitz, Jeremias (CR51) 2019; 139
Mehta, Cannon, Fox, Wallentin, Boden, Spacek (CR3) 2005; 293
van de Hoef, Meuwissen, Escaned, Sen, Petraco, van Lavieren, Echavarria-Pinto, Nolte, Nijjer, Chamuleau, Voskuil, van Eck-Smit, Verberne, Henriques, Koch, de Winter, Spaan, Siebes, Tijssen, Davies, Piek (CR24) 2015; 11
Legalery, Schiele, Seronde, Meneveau, Wei, Didier, Blonde, Caulfield, Bassand (CR13) 2005; 26
Neumann, Sousa-Uva, Ahlsson, Alfonso, Banning, Benedetto, Byrne, Collet, Falk, Head, Jüni, Kastrati, Koller, Kristensen, Niebauer, Richter, Seferović, Sibbing, Stefanini, Windecker, Yadav, Zembala (CR15) 2019; 14
Papafaklis, Muramatsu, Ishibashi, Lakkas, Nakatani, Bourantas, Ligthart, Onuma, Echavarria-Pinto, Tsirka, Kotsia, Nikas, Mogabgab, van Geuns, Naka, Fotiadis, Brilakis, Garcia-Garcia, Escaned, Zijlstra, Michalis, Serruys (CR43) 2014; 10
CR46
Gotberg, Christiansen, Gudmundsdottir, Sandhall, Danielewicz, Jakobsen (CR26) 2017; 376
Gorlin, Dexter (CR40) 1952; 43
de Waard, Danad, Petraco, Driessen, Raijmakers, Teunissen, van de Ven, van Leeuwen, Nap, Harms, Lammertsma, Davies, Knaapen, van Royen (CR23) 2018; 39
Pijls, Klauss, Siebert, Powers, Takazawa, Fearon, Escaned, Tsurumi, Akasaka, Samady, de Bruyne (CR56) 2002; 105
Tu, Westra, Yang, von Birgelen, Ferrara, Pellicano, Nef, Tebaldi, Murasato, Lansky, Barbato, van der Heijden, Reiber, Holm, Wijns (CR47) 2016; 9
Morris, Silva Soto, Feher, Rafiroiu, Lungu, Varma, Lawford, Hose, Gunn (CR39) 2017; 2
Kogame, Ono, Kawashima, Tomaniak, Hara, Leipsic (CR18) 2020; 13
Ahmad, Vendrik, Eftekhari, Howard, Cook, Rajkumar, Malik, Mikhail, Ruparelia, Hadjiloizou, Nijjer, al-Lamee, Petraco, Warisawa, Wijntjens, Koch, van de Hoef, de Waard, Echavarria-Pinto, Frame, Sutaria, Kanaganayagam, Ariff, Anderson, Chukwuemeka, Fertleman, Koul, Iglesias, Francis, Mayet, Serruys, Davies, Escaned, van Royen, Götberg, Juhl Terkelsen, Høj Christiansen, Piek, Baan, Sen (CR32) 2019; 12
Nam, Hur, Cho, Park, Yoon, Kim, Chung, Kim, Kim, Doh, Koo, Tahk, Fearon (CR57) 2011; 107
Chowdhury, Osborn (CR5) 2020; 22
Morris, Narracott, von Tengg-Kobligk, Silva Soto, Hsiao, Lungu, Evans, Bressloff, Lawford, Hose, Gunn (CR42) 2016; 102
Gotberg, Cook, Sen, Nijjer, Escaned, Davies (CR17) 2017; 70
Levine, Bates, Blankenship, Bailey, Bittl, Cercek (CR16) 2011; 124
Tonino, De Bruyne, Pijls, Siebert, Ikeno, van’t Veer (CR10) 2009; 360
Agarwal, Kasula, Hacioglu, Ahmed, Uretsky, Hakeem (CR52) 2016; 9
De Bruyne, Pijls, Kalesan, Barbato, Tonino, Piroth (CR8) 2012; 367
Westra, Tu, Winther, Nissen, Vestergaard, Andersen, Holck, Fox Maule, Johansen, Andreasen, Simonsen, Zhang, Kristensen, Maeng, Kaltoft, Terkelsen, Krusell, Jakobsen, Reiber, Lassen, Bøttcher, Bøtker, Christiansen, Holm (CR48) 2018; 11
Petraco, Escaned, Sen, Nijjer, Asrress, Echavarria-Pinto, Lockie, Khawaja, Cuevas, Foin, Broyd, Foale, Hadjiloizou, Malik, Mikhail, Sethi, Kaprielian, Baker, Lefroy, Bellamy, al-Bustami, Khan, Hughes, Francis, Mayet, di Mario, Redwood, Davies (CR21) 2013; 9
Siogkas, Papafaklis, Lakkas, Exarchos, Karmpaliotis, Ali, Pelosi, Parodi, Katsouras, Fotiadis, Michalis (CR45) 2019; 28
Westra, Andersen, Campo, Matsuo, Koltowski, Eftekhari (CR49) 2018; 7
Van Herck, Carlier, Claeys, Haine, Gorissen, Miljoen (CR30) 2007; 93
Kim, Feldman, Swaminathan, Minutello, Chanin, Yang, Lee, Charitakis, Shah, Kaple, Bergman, Singh, Wong (CR1) 2014; 114
Halon (CR7) 2018; 270
Morris, van de Vosse, Lawford, Hose, Gunn (CR34) 2015; 8
Jeremias, Maehara, Genereux, Asrress, Berry, De Bruyne (CR27) 2014; 63
Sen, Escaned, Malik, Mikhail, Foale, Mila, Tarkin, Petraco, Broyd, Jabbour, Sethi, Baker, Bellamy, al-Bustami, Hackett, Khan, Lefroy, Parker, Hughes, Francis, di Mario, Mayet, Davies (CR20) 2012; 59
Rajappan, Rimoldi, Camici, Bellenger, Pennell, Sheridan (CR31) 2003; 107
Patel, Calhoon, Dehmer, Grantham, Maddox, Maron (CR19) 2017; 69
Jeremias, Kirtane, Stone (CR2) 2017; 69
Taylor, Fonte, Min (CR37) 2013; 61
Katritsis, Webb-Peploe (CR6) 1991; 14
Tebaldi, Biscaglia, Fineschi, Musumeci, Marchese, Leone, Rossi, Stefanini, Maione, Menozzi, Tarantino, Lodolini, Gallo, Barbato, Tarantini, Campo (CR54) 2018; 11
Pijls, De Bruyne, Peels, Van Der Voort, Bonnier, Bartunek (CR11) 1996; 334
Hwang, Jeon, Lee, Park, Kim, Tong, Zhang, Bang, Suh, Paeng, Na, Cheon, Cook, Davies, Koo (CR22) 2017; 10
Siogkas, Anagnostopoulos, Liga, Exarchos, Sakellarios, Rigas, Scholte, Papafaklis, Loggitsi, Pelosi, Parodi, Maaniitty, Michalis, Knuuti, Neglia, Fotiadis (CR44) 2019; 29
Papafaklis, Baumbach (CR36) 2019; 139
Lee, Choi, Park, Hwang, Rhee, Kim, Park, Kim, Jung, Cho, Yoon, Song, Hahn, Nam, Shin, Doh, Hur, Koo (CR33) 2019; 139
Masdjedi, van Zandvoort, Balbi, Gijsen, Ligthart, Rutten (CR41) 2020; 16
Jeremias, Davies, Maehara, Matsumura, Schneider, Tang, Talwar, Marques, Shammas, Gruberg, Seto, Samady, Sharp, Ali, Mintz, Patel, Stone (CR53) 2019; 12
Warisawa, Cook, Howard, Ahmad, Doi, Nakayama, Goto, Yakuta, Karube, Shun-Shin, Petraco, Sen, Nijjer, al Lamee, Ishibashi, Matsuda, Escaned, di Mario, Francis, Akashi, Davies (CR28) 2019; 12
Taqueti, Di Carli (CR29) 2018; 72
JE Davies (9554_CR25) 2017; 376
NH Pijls (9554_CR56) 2002; 105
PK Siogkas (9554_CR45) 2019; 28
CA Taylor (9554_CR37) 2013; 61
T Warisawa (9554_CR28) 2019; 12
PD Morris (9554_CR34) 2015; 8
P Legalery (9554_CR13) 2005; 26
FJ Neumann (9554_CR15) 2019; 14
NH Pijls (9554_CR11) 1996; 334
M Chowdhury (9554_CR5) 2020; 22
M Gotberg (9554_CR17) 2017; 70
VR Taqueti (9554_CR29) 2018; 72
WF Fearon (9554_CR51) 2019; 139
PD Morris (9554_CR42) 2016; 102
SR Mehta (9554_CR3) 2005; 293
PD Morris (9554_CR39) 2017; 2
RC Gosling (9554_CR55) 2019; 12
9554_CR46
MI Papafaklis (9554_CR43) 2014; 10
N Kogame (9554_CR18) 2020; 13
M Tebaldi (9554_CR54) 2018; 11
J Westra (9554_CR49) 2018; 7
B Xu (9554_CR50) 2017; 70
A Jeremias (9554_CR27) 2014; 63
Y Ahmad (9554_CR32) 2019; 12
K Masdjedi (9554_CR41) 2020; 16
S Tu (9554_CR47) 2016; 9
GA de Waard (9554_CR23) 2018; 39
NH Pijls (9554_CR9) 1993; 87
JM Lee (9554_CR33) 2019; 139
D Katritsis (9554_CR6) 1991; 14
LK Kim (9554_CR1) 2014; 114
GN Levine (9554_CR16) 2011; 124
SK Agarwal (9554_CR52) 2016; 9
R Gorlin (9554_CR40) 1952; 43
K Rajappan (9554_CR31) 2003; 107
B De Bruyne (9554_CR8) 2012; 367
MI Papafaklis (9554_CR36) 2019; 139
J Adjedj (9554_CR14) 2016; 133
A Jeremias (9554_CR2) 2017; 69
CW Nam (9554_CR57) 2011; 107
PK Siogkas (9554_CR44) 2019; 29
FM Zimmermann (9554_CR12) 2015; 36
M Gotberg (9554_CR26) 2017; 376
DJ Maron (9554_CR4) 2020; 382
R Petraco (9554_CR21) 2013; 9
PA Tonino (9554_CR10) 2009; 360
J Westra (9554_CR48) 2018; 11
A Jeremias (9554_CR53) 2019; 12
S Sen (9554_CR20) 2012; 59
DA Halon (9554_CR7) 2018; 270
TP van de Hoef (9554_CR24) 2015; 11
K Chahour (9554_CR35) 2020; 2020
PD Morris (9554_CR38) 2013; 6
PL Van Herck (9554_CR30) 2007; 93
MR Patel (9554_CR19) 2017; 69
D Hwang (9554_CR22) 2017; 10
References_xml – volume: 43
  start-page: 188
  issue: 2
  year: 1952
  end-page: 205
  ident: CR40
  article-title: Hydraulic formula for the calculation of the cross-sectional area of the mitral valve during regurgitation
  publication-title: Am Heart J
  doi: 10.1016/0002-8703(52)90210-x
– volume: 70
  start-page: 1379
  issue: 11
  year: 2017
  end-page: 1402
  ident: CR17
  article-title: The Evolving future of instantaneous wave-free ratio and fractional flow reserve
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.07.770
– volume: 63
  start-page: 1253
  issue: 13
  year: 2014
  end-page: 1261
  ident: CR27
  article-title: Multicenter core laboratory comparison of the instantaneous wave-free ratio and resting Pd/Pa with fractional flow reserve: the RESOLVE study
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2013.09.060
– volume: 105
  start-page: 2950
  issue: 25
  year: 2002
  end-page: 2954
  ident: CR56
  article-title: Coronary pressure measurement after stenting predicts adverse events at follow-up: a multicenter registry
  publication-title: Circulation.
  doi: 10.1161/01.cir.0000020547.92091.76
– volume: 114
  start-page: 1003
  issue: 7
  year: 2014
  end-page: 1010
  ident: CR1
  article-title: Rate of percutaneous coronary intervention for the management of acute coronary syndromes and stable coronary artery disease in the United States (2007 to 2011)
  publication-title: Am J Cardiol
  doi: 10.1016/j.amjcard.2014.07.013
– volume: 10
  start-page: 751
  issue: 8
  year: 2017
  end-page: 760
  ident: CR22
  article-title: Diagnostic performance of resting and hyperemic invasive physiological indices to define myocardial ischemia: validation with (13)N-ammonia positron emission tomography
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2016.12.015
– volume: 93
  start-page: 1231
  issue: 10
  year: 2007
  end-page: 1237
  ident: CR30
  article-title: Coronary microvascular dysfunction after myocardial infarction: increased coronary zero flow pressure both in the infarcted and in the remote myocardium is mainly related to left ventricular filling pressure
  publication-title: Heart.
  doi: 10.1136/hrt.2006.100818
– volume: 13
  start-page: 1617
  issue: 14
  year: 2020
  end-page: 1638
  ident: CR18
  article-title: The impact of coronary physiology on contemporary clinical decision making
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2020.04.040
– volume: 12
  issue: 5
  year: 2019
  ident: CR28
  article-title: Physiological pattern of disease assessed by pressure-wire pullback has an influence on fractional flow reserve/instantaneous wave-free ratio discordance
  publication-title: Circ Cardiovasc Interv
  doi: 10.1161/CIRCINTERVENTIONS.118.007494
– volume: 70
  start-page: 3077
  issue: 25
  year: 2017
  end-page: 3087
  ident: CR50
  article-title: Diagnostic accuracy of angiography-based quantitative flow ratio measurements for online assessment of coronary stenosis
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.10.035
– volume: 11
  start-page: 914
  issue: 8
  year: 2015
  end-page: 925
  ident: CR24
  article-title: Head-to-head comparison of basal stenosis resistance index, instantaneous wave-free ratio, and fractional flow reserve: diagnostic accuracy for stenosis-specific myocardial ischaemia
  publication-title: EuroIntervention.
  doi: 10.4244/EIJY14M08_17
– volume: 26
  start-page: 2623
  issue: 24
  year: 2005
  end-page: 2629
  ident: CR13
  article-title: One-year outcome of patients submitted to routine fractional flow reserve assessment to determine the need for angioplasty
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehi484
– volume: 102
  start-page: 18
  issue: 1
  year: 2016
  end-page: 28
  ident: CR42
  article-title: Computational fluid dynamics modelling in cardiovascular medicine
  publication-title: Heart.
  doi: 10.1136/heartjnl-2015-308044
– volume: 12
  start-page: e008263
  issue: 12
  year: 2019
  ident: CR32
  article-title: Determining the predominant lesion in patients with severe aortic stenosis and coronary stenoses: a multicenter study using intracoronary pressure and flow
  publication-title: Circ Cardiovasc Interv
  doi: 10.1161/CIRCINTERVENTIONS.119.008263
– volume: 2020
  start-page: 3942152
  year: 2020
  end-page: 3942114
  ident: CR35
  article-title: Virtual FFR Quantified with a generalized flow model using windkessel boundary conditions
  publication-title: Comput Math Methods Med
  doi: 10.1155/2020/3942152
– volume: 69
  start-page: 2748
  issue: 22
  year: 2017
  end-page: 2758
  ident: CR2
  article-title: A test in context: fractional flow reserve: accuracy, prognostic implications, and limitations
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.04.019
– volume: 22
  start-page: 2
  issue: 1
  year: 2020
  ident: CR5
  article-title: Physiological assessment of coronary lesions in 2020
  publication-title: Curr Treat Options Cardiovasc Med
  doi: 10.1007/s11936-020-0803-7
– ident: CR46
– volume: 36
  start-page: 3182
  issue: 45
  year: 2015
  end-page: 3188
  ident: CR12
  article-title: Deferral vs. performance of percutaneous coronary intervention of functionally non-significant coronary stenosis: 15-year follow-up of the DEFER trial
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehv452
– volume: 11
  start-page: e007107
  issue: 3
  year: 2018
  ident: CR48
  article-title: Evaluation of coronary artery stenosis by quantitative flow ratio during invasive coronary angiography: The WIFI II study (wire-free functional imaging II)
  publication-title: Circ Cardiovasc Imaging
  doi: 10.1161/CIRCIMAGING.117.007107
– volume: 11
  start-page: 1482
  issue: 15
  year: 2018
  end-page: 1491
  ident: CR54
  article-title: Evolving routine standards in invasive hemodynamic assessment of coronary stenosis: the Nationwide Italian SICI-GISE Cross-Sectional ERIS Study
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2018.04.037
– volume: 9
  start-page: 2024
  issue: 19
  year: 2016
  end-page: 2035
  ident: CR47
  article-title: Diagnostic accuracy of fast computational approaches to derive fractional flow reserve from diagnostic coronary angiography: the International Multicenter FAVOR Pilot Study
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2016.07.013
– volume: 9
  start-page: 1022
  issue: 10
  year: 2016
  end-page: 1031
  ident: CR52
  article-title: Utilizing post-intervention fractional flow reserve to optimize acute results and the relationship to long-term outcomes
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2016.01.046
– volume: 139
  start-page: 477
  issue: 4
  year: 2019
  end-page: 484
  ident: CR51
  article-title: Accuracy of fractional flow reserve derived from coronary angiography
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.118.037350
– volume: 87
  start-page: 1354
  issue: 4
  year: 1993
  end-page: 1367
  ident: CR9
  article-title: Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty
  publication-title: Circulation.
  doi: 10.1161/01.cir.87.4.1354
– volume: 7
  start-page: e009603
  issue: 14
  year: 2018
  ident: CR49
  article-title: Diagnostic performance of in-procedure angiography-derived quantitative flow reserve compared to pressure-derived fractional flow reserve: the FAVOR II Europe-Japan study
  publication-title: J Am Heart Assoc
  doi: 10.1161/JAHA.118.009603
– volume: 72
  start-page: 2625
  issue: 21
  year: 2018
  end-page: 2641
  ident: CR29
  article-title: Coronary microvascular disease pathogenic mechanisms and therapeutic options: JACC state-of-the-art review
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2018.09.042
– volume: 28
  start-page: e33
  issue: 4
  year: 2019
  end-page: ee6
  ident: CR45
  article-title: Virtual functional assessment of coronary stenoses using intravascular ultrasound imaging: a proof-of-concept pilot study
  publication-title: Heart Lung Circ
  doi: 10.1016/j.hlc.2018.02.011
– volume: 6
  start-page: 149
  issue: 2
  year: 2013
  end-page: 157
  ident: CR38
  article-title: Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve From Coronary Angiography) study
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2012.08.024
– volume: 107
  start-page: 3170
  issue: 25
  year: 2003
  end-page: 3175
  ident: CR31
  article-title: Functional changes in coronary microcirculation after valve replacement in patients with aortic stenosis
  publication-title: Circulation.
  doi: 10.1161/01.CIR.0000074211.28917.31
– volume: 367
  start-page: 991
  issue: 11
  year: 2012
  end-page: 1001
  ident: CR8
  article-title: Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1205361
– volume: 9
  start-page: 91
  issue: 1
  year: 2013
  end-page: 101
  ident: CR21
  article-title: Classification performance of instantaneous wave-free ratio (iFR) and fractional flow reserve in a clinical population of intermediate coronary stenoses: results of the ADVISE registry
  publication-title: EuroIntervention.
  doi: 10.4244/EIJV9I1A14
– volume: 14
  start-page: 1435
  issue: 14
  year: 2019
  end-page: 1534
  ident: CR15
  article-title: 2018 ESC/EACTS Guidelines on myocardial revascularization
  publication-title: EuroIntervention.
  doi: 10.4244/EIJY19M01_01
– volume: 39
  start-page: 4072
  issue: 46
  year: 2018
  end-page: 4081
  ident: CR23
  article-title: Fractional flow reserve, instantaneous wave-free ratio, and resting Pd/Pa compared with [15O]H2O positron emission tomography myocardial perfusion imaging: a PACIFIC trial sub-study
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehy632
– volume: 69
  start-page: 2212
  issue: 17
  year: 2017
  end-page: 2241
  ident: CR19
  article-title: ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 appropriate use criteria for coronary revascularization in patients with stable ischemic heart disease: a report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society of Thoracic Surgeons
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.02.001
– volume: 10
  start-page: 574
  issue: 5
  year: 2014
  end-page: 583
  ident: CR43
  article-title: Fast virtual functional assessment of intermediate coronary lesions using routine angiographic data and blood flow simulation in humans: comparison with pressure wire - fractional flow reserve
  publication-title: EuroIntervention.
  doi: 10.4244/EIJY14M07_01
– volume: 376
  start-page: 1824
  issue: 19
  year: 2017
  end-page: 1834
  ident: CR25
  article-title: Use of the instantaneous wave-free ratio or fractional flow reserve in PCI
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1700445
– volume: 139
  start-page: 485
  issue: 4
  year: 2019
  end-page: 488
  ident: CR36
  article-title: from lumenogram to "functional angiography" and the evolution of virtual fractional flow reserve
  publication-title: Circulation.
  doi: 10.1161/CIRCULATIONAHA.118.037528
– volume: 360
  start-page: 213
  issue: 3
  year: 2009
  end-page: 224
  ident: CR10
  article-title: Fractional flow reserve versus angiography for guiding percutaneous coronary intervention
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa0807611
– volume: 8
  start-page: 1009
  issue: 8
  year: 2015
  end-page: 1017
  ident: CR34
  article-title: "Virtual" (computed) fractional flow reserve: current challenges and limitations
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2015.04.006
– volume: 12
  start-page: 1991
  issue: 20
  year: 2019
  end-page: 2001
  ident: CR53
  article-title: Blinded physiological assessment of residual ischemia after successful angiographic percutaneous coronary intervention: The DEFINE PCI study
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2019.05.054
– volume: 334
  start-page: 1703
  issue: 26
  year: 1996
  end-page: 1708
  ident: CR11
  article-title: Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses
  publication-title: N Engl J Med
  doi: 10.1056/NEJM199606273342604
– volume: 14
  start-page: 20
  issue: 1
  year: 1991
  end-page: 24
  ident: CR6
  article-title: Limitations of coronary angiography: an underestimated problem?
  publication-title: Clin Cardiol
  doi: 10.1002/clc.4960140106
– volume: 12
  start-page: 865
  issue: 5
  year: 2019
  end-page: 872
  ident: CR55
  article-title: Virtual coronary intervention: a treatment planning tool based upon the angiogram
  publication-title: JACC Cardiovasc Imaging
  doi: 10.1016/j.jcmg.2018.01.019
– volume: 270
  start-page: 74
  year: 2018
  end-page: 75
  ident: CR7
  article-title: Can angiography predict physiology?
  publication-title: Int J Cardiol
  doi: 10.1016/j.ijcard.2018.07.029
– volume: 133
  start-page: 502
  issue: 5
  year: 2016
  end-page: 508
  ident: CR14
  article-title: Significance of intermediate values of fractional flow reserve in patients with coronary artery disease
  publication-title: Circulation.
  doi: 10.1161/CIRCULATIONAHA.115.018747
– volume: 16
  start-page: 591
  issue: 7
  year: 2020
  end-page: 599
  ident: CR41
  article-title: Validation of a three-dimensional quantitative coronary angiography-based software to calculate fractional flow reserve: the FAST study
  publication-title: EuroIntervention
  doi: 10.4244/EIJ-D-19-00466
– volume: 61
  start-page: 2233
  issue: 22
  year: 2013
  end-page: 2241
  ident: CR37
  article-title: Computational fluid dynamics applied to cardiac computed tomography for noninvasive quantification of fractional flow reserve: scientific basis
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2012.11.083
– volume: 29
  start-page: 2117
  issue: 4
  year: 2019
  end-page: 2126
  ident: CR44
  article-title: Noninvasive CT-based hemodynamic assessment of coronary lesions derived from fast computational analysis: a comparison against fractional flow reserve
  publication-title: Eur Radiol
  doi: 10.1007/s00330-018-5781-8
– volume: 107
  start-page: 1763
  issue: 12
  year: 2011
  end-page: 1767
  ident: CR57
  article-title: Relation of fractional flow reserve after drug-eluting stent implantation to one-year outcomes
  publication-title: Am J Cardiol
  doi: 10.1016/j.amjcard.2011.02.329
– volume: 2
  start-page: 434
  issue: 4
  year: 2017
  end-page: 446
  ident: CR39
  article-title: Fast virtual fractional flow reserve based upon steady-state computational fluid dynamics analysis: results from the VIRTU-fast study
  publication-title: JACC Basic Transl Sci
  doi: 10.1016/j.jacbts.2017.04.003
– volume: 293
  start-page: 2908
  issue: 23
  year: 2005
  end-page: 2917
  ident: CR3
  article-title: Routine vs selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials
  publication-title: JAMA.
  doi: 10.1001/jama.293.23.2908
– volume: 382
  start-page: 1395
  issue: 15
  year: 2020
  end-page: 1407
  ident: CR4
  article-title: Initial invasive or conservative strategy for stable coronary disease
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1915922
– volume: 59
  start-page: 1392
  issue: 15
  year: 2012
  end-page: 1402
  ident: CR20
  article-title: Development and validation of a new adenosine-independent index of stenosis severity from coronary wave-intensity analysis: results of the ADVISE (ADenosine Vasodilator Independent Stenosis Evaluation) study
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2011.11.003
– volume: 124
  start-page: e574
  issue: 23
  year: 2011
  end-page: e651
  ident: CR16
  article-title: 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions
  publication-title: Circulation.
  doi: 10.1161/CIR.0b013e31823ba622
– volume: 376
  start-page: 1813
  issue: 19
  year: 2017
  end-page: 1823
  ident: CR26
  article-title: Instantaneous wave-free ratio versus fractional flow reserve to guide PCI
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1616540
– volume: 139
  start-page: 889
  issue: 7
  year: 2019
  end-page: 900
  ident: CR33
  article-title: Physiological and clinical assessment of resting physiological indexes
  publication-title: Circulation.
  doi: 10.1161/CIRCULATIONAHA.118.037021
– volume: 7
  start-page: e009603
  issue: 14
  year: 2018
  ident: 9554_CR49
  publication-title: J Am Heart Assoc
  doi: 10.1161/JAHA.118.009603
– volume: 14
  start-page: 20
  issue: 1
  year: 1991
  ident: 9554_CR6
  publication-title: Clin Cardiol
  doi: 10.1002/clc.4960140106
– volume: 22
  start-page: 2
  issue: 1
  year: 2020
  ident: 9554_CR5
  publication-title: Curr Treat Options Cardiovasc Med
  doi: 10.1007/s11936-020-0803-7
– ident: 9554_CR46
  doi: 10.1002/ccd.29558
– volume: 69
  start-page: 2748
  issue: 22
  year: 2017
  ident: 9554_CR2
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.04.019
– volume: 10
  start-page: 574
  issue: 5
  year: 2014
  ident: 9554_CR43
  publication-title: EuroIntervention.
  doi: 10.4244/EIJY14M07_01
– volume: 87
  start-page: 1354
  issue: 4
  year: 1993
  ident: 9554_CR9
  publication-title: Circulation.
  doi: 10.1161/01.cir.87.4.1354
– volume: 12
  issue: 5
  year: 2019
  ident: 9554_CR28
  publication-title: Circ Cardiovasc Interv
  doi: 10.1161/CIRCINTERVENTIONS.118.007494
– volume: 39
  start-page: 4072
  issue: 46
  year: 2018
  ident: 9554_CR23
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehy632
– volume: 61
  start-page: 2233
  issue: 22
  year: 2013
  ident: 9554_CR37
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2012.11.083
– volume: 59
  start-page: 1392
  issue: 15
  year: 2012
  ident: 9554_CR20
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2011.11.003
– volume: 28
  start-page: e33
  issue: 4
  year: 2019
  ident: 9554_CR45
  publication-title: Heart Lung Circ
  doi: 10.1016/j.hlc.2018.02.011
– volume: 139
  start-page: 477
  issue: 4
  year: 2019
  ident: 9554_CR51
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.118.037350
– volume: 114
  start-page: 1003
  issue: 7
  year: 2014
  ident: 9554_CR1
  publication-title: Am J Cardiol
  doi: 10.1016/j.amjcard.2014.07.013
– volume: 139
  start-page: 485
  issue: 4
  year: 2019
  ident: 9554_CR36
  publication-title: Circulation.
  doi: 10.1161/CIRCULATIONAHA.118.037528
– volume: 382
  start-page: 1395
  issue: 15
  year: 2020
  ident: 9554_CR4
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1915922
– volume: 133
  start-page: 502
  issue: 5
  year: 2016
  ident: 9554_CR14
  publication-title: Circulation.
  doi: 10.1161/CIRCULATIONAHA.115.018747
– volume: 70
  start-page: 1379
  issue: 11
  year: 2017
  ident: 9554_CR17
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.07.770
– volume: 105
  start-page: 2950
  issue: 25
  year: 2002
  ident: 9554_CR56
  publication-title: Circulation.
  doi: 10.1161/01.cir.0000020547.92091.76
– volume: 6
  start-page: 149
  issue: 2
  year: 2013
  ident: 9554_CR38
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2012.08.024
– volume: 11
  start-page: 914
  issue: 8
  year: 2015
  ident: 9554_CR24
  publication-title: EuroIntervention.
  doi: 10.4244/EIJY14M08_17
– volume: 376
  start-page: 1824
  issue: 19
  year: 2017
  ident: 9554_CR25
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1700445
– volume: 102
  start-page: 18
  issue: 1
  year: 2016
  ident: 9554_CR42
  publication-title: Heart.
  doi: 10.1136/heartjnl-2015-308044
– volume: 29
  start-page: 2117
  issue: 4
  year: 2019
  ident: 9554_CR44
  publication-title: Eur Radiol
  doi: 10.1007/s00330-018-5781-8
– volume: 360
  start-page: 213
  issue: 3
  year: 2009
  ident: 9554_CR10
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa0807611
– volume: 14
  start-page: 1435
  issue: 14
  year: 2019
  ident: 9554_CR15
  publication-title: EuroIntervention.
  doi: 10.4244/EIJY19M01_01
– volume: 72
  start-page: 2625
  issue: 21
  year: 2018
  ident: 9554_CR29
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2018.09.042
– volume: 11
  start-page: 1482
  issue: 15
  year: 2018
  ident: 9554_CR54
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2018.04.037
– volume: 43
  start-page: 188
  issue: 2
  year: 1952
  ident: 9554_CR40
  publication-title: Am Heart J
  doi: 10.1016/0002-8703(52)90210-x
– volume: 9
  start-page: 91
  issue: 1
  year: 2013
  ident: 9554_CR21
  publication-title: EuroIntervention.
  doi: 10.4244/EIJV9I1A14
– volume: 36
  start-page: 3182
  issue: 45
  year: 2015
  ident: 9554_CR12
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehv452
– volume: 2020
  start-page: 3942152
  year: 2020
  ident: 9554_CR35
  publication-title: Comput Math Methods Med
  doi: 10.1155/2020/3942152
– volume: 12
  start-page: e008263
  issue: 12
  year: 2019
  ident: 9554_CR32
  publication-title: Circ Cardiovasc Interv
  doi: 10.1161/CIRCINTERVENTIONS.119.008263
– volume: 13
  start-page: 1617
  issue: 14
  year: 2020
  ident: 9554_CR18
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2020.04.040
– volume: 10
  start-page: 751
  issue: 8
  year: 2017
  ident: 9554_CR22
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2016.12.015
– volume: 12
  start-page: 865
  issue: 5
  year: 2019
  ident: 9554_CR55
  publication-title: JACC Cardiovasc Imaging
  doi: 10.1016/j.jcmg.2018.01.019
– volume: 26
  start-page: 2623
  issue: 24
  year: 2005
  ident: 9554_CR13
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehi484
– volume: 9
  start-page: 1022
  issue: 10
  year: 2016
  ident: 9554_CR52
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2016.01.046
– volume: 124
  start-page: e574
  issue: 23
  year: 2011
  ident: 9554_CR16
  publication-title: Circulation.
  doi: 10.1161/CIR.0b013e31823ba622
– volume: 9
  start-page: 2024
  issue: 19
  year: 2016
  ident: 9554_CR47
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2016.07.013
– volume: 334
  start-page: 1703
  issue: 26
  year: 1996
  ident: 9554_CR11
  publication-title: N Engl J Med
  doi: 10.1056/NEJM199606273342604
– volume: 107
  start-page: 3170
  issue: 25
  year: 2003
  ident: 9554_CR31
  publication-title: Circulation.
  doi: 10.1161/01.CIR.0000074211.28917.31
– volume: 367
  start-page: 991
  issue: 11
  year: 2012
  ident: 9554_CR8
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1205361
– volume: 70
  start-page: 3077
  issue: 25
  year: 2017
  ident: 9554_CR50
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.10.035
– volume: 93
  start-page: 1231
  issue: 10
  year: 2007
  ident: 9554_CR30
  publication-title: Heart.
  doi: 10.1136/hrt.2006.100818
– volume: 139
  start-page: 889
  issue: 7
  year: 2019
  ident: 9554_CR33
  publication-title: Circulation.
  doi: 10.1161/CIRCULATIONAHA.118.037021
– volume: 69
  start-page: 2212
  issue: 17
  year: 2017
  ident: 9554_CR19
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2017.02.001
– volume: 8
  start-page: 1009
  issue: 8
  year: 2015
  ident: 9554_CR34
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2015.04.006
– volume: 12
  start-page: 1991
  issue: 20
  year: 2019
  ident: 9554_CR53
  publication-title: JACC Cardiovasc Interv
  doi: 10.1016/j.jcin.2019.05.054
– volume: 376
  start-page: 1813
  issue: 19
  year: 2017
  ident: 9554_CR26
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa1616540
– volume: 2
  start-page: 434
  issue: 4
  year: 2017
  ident: 9554_CR39
  publication-title: JACC Basic Transl Sci
  doi: 10.1016/j.jacbts.2017.04.003
– volume: 107
  start-page: 1763
  issue: 12
  year: 2011
  ident: 9554_CR57
  publication-title: Am J Cardiol
  doi: 10.1016/j.amjcard.2011.02.329
– volume: 293
  start-page: 2908
  issue: 23
  year: 2005
  ident: 9554_CR3
  publication-title: JAMA.
  doi: 10.1001/jama.293.23.2908
– volume: 16
  start-page: 591
  issue: 7
  year: 2020
  ident: 9554_CR41
  publication-title: EuroIntervention
  doi: 10.4244/EIJ-D-19-00466
– volume: 270
  start-page: 74
  year: 2018
  ident: 9554_CR7
  publication-title: Int J Cardiol
  doi: 10.1016/j.ijcard.2018.07.029
– volume: 11
  start-page: e007107
  issue: 3
  year: 2018
  ident: 9554_CR48
  publication-title: Circ Cardiovasc Imaging
  doi: 10.1161/CIRCIMAGING.117.007107
– volume: 63
  start-page: 1253
  issue: 13
  year: 2014
  ident: 9554_CR27
  publication-title: J Am Coll Cardiol
  doi: 10.1016/j.jacc.2013.09.060
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Snippet Purpose of Review In this review, we summarize the use of virtual physiologic functional assessments of coronary artery disease and their utility to guide...
Purpose of ReviewIn this review, we summarize the use of virtual physiologic functional assessments of coronary artery disease and their utility to guide...
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SubjectTerms Angiography
Assessments
Cardiology
Cardiovascular disease
Coronary artery disease
Decision making
Diagnostic Radiology
Imaging
Interventional Radiology
Intravascular Imaging (A.G. Truesdell
Medicine
Medicine & Public Health
Nuclear Medicine
Pressure ratio
Radiology
Section Editor
Topical Collection on Intravascular Imaging
Ultrasound
Wire
Title The Evolution of Virtual Physiologic Assessments and Virtual Coronary Intervention to Optimize Revascularization
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