Antioxidative and neuroprotective effects of volatile components in essential oils from Chrysanthemum indicum Linné flowers

• Published in: Food science and biotechnology Vol. 24; no. 2; pp. 717 - 723
• Main Authors: Lee, Bong Han, Nam, Tea Gyu, Park, Woo Jung, Kang, Hee, Heo, Ho Jin, Chung, Dae Kyun, Kim, Gun Hee, Kim, Dae-Ok
• Format: Journal Article
• Language: English
• Published: Heidelberg The Korean Society of Food Science and Technology 01.04.2015; 한국식품과학회
• Subjects: Chemistry; Chemistry and Materials Science; Chrysanthemum; Food Science; Nutrition; Research Article; 식품과학; GC-MS; thymol; anticholinesterase activity; oxidative stress; vitamin C equivalent antioxidant capacity
• ISSN: 1226-7708; 2092-6456
• DOI: 10.1007/s10068-015-0093-0

Chrysanthemum indicum Linné, belonging to the family Compositae, is a perennial herb that is widespread in Korea. C. indicum Linné flowers have been traditionally used as an oriental medicine for treatment of infectious diseases. The chemical compositions, antioxidant capacity, and neuroprotective effects of volatile components in essential oils from C. indicum Linné flowers were investigated. GC-MS analysis of essential oils revealed the 15 major components of 1,8-cineole, o -cymene, camphor, pinocarvone, chrysanthenyl acetate, bornyl acetate, trans -caryophyllene, terpinen-4-ol, umbellulone, trans -pinocarveol, cis -verbenol, borneol, α-terpineol, caryophyllene oxide, and thymol. Thymol had the highest antioxidant capacity. Essential oils and thymol dose-dependently decreased intracellular oxidative stress, exhibited anticholinesterase activities, and increased the cell viability of neuronal PC-12 cells. Essential oils and thymol from C. indicum Linné flowers can be sources of natural antioxidants and functional foods.