A Case of Appendiceal Metastasis from Lung Cancer with Acute Appendicitis

We repossrt a case of appendiceal metastasis from lung cancer with acute appendicitis. A 65-year-old man underwent left pneumonectomy and mediastinum lymphnode dissection for left lobe lung cancer at the age of 64. Nine months later, suffered recurrent lymph node metastasis undergoing radiation ther...

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Published inNippon Shokaki Geka Gakkai zasshi Vol. 40; no. 2; pp. 215 - 220
Main Authors Ohkouchi, Nobuhiro, Fukuzawa, Junya, Yamamoto, Masayoshi, Yanagisawa, Kazuhiko
Format Journal Article
LanguageJapanese
Published The Japanese Society of Gastroenterological Surgery 2007
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ISSN0386-9768
1348-9372
DOI10.5833/jjgs.40.215

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Abstract We repossrt a case of appendiceal metastasis from lung cancer with acute appendicitis. A 65-year-old man underwent left pneumonectomy and mediastinum lymphnode dissection for left lobe lung cancer at the age of 64. Nine months later, suffered recurrent lymph node metastasis undergoing radiation therapy. He suffered right lower abdominal pain during radiation therapy, found to be due to acute appendicitis with a tumor. He received antibiotic therapy with fasting, temporarily improving, but an appendicitis requiring surgery. The surgical specimen showed a 6cm mass on the back of the cecum. This tumor was diagnosed as appendiceal metastasis because the histology of carcinoma resembled the previous specimen from left lung cancer. Pathological findings showed poorly differentiated adenocarcinoma with abscess formation. Carcinoma mainly involves proper muscles and invades the mucosa and subserosa. He died of pneumonia 12 months after his last surgery. We discuss therapy for metastatic appendiceal tumor with appendicitis in cancer patients and review the literature.
AbstractList We repossrt a case of appendiceal metastasis from lung cancer with acute appendicitis. A 65-year-old man underwent left pneumonectomy and mediastinum lymphnode dissection for left lobe lung cancer at the age of 64. Nine months later, suffered recurrent lymph node metastasis undergoing radiation therapy. He suffered right lower abdominal pain during radiation therapy, found to be due to acute appendicitis with a tumor. He received antibiotic therapy with fasting, temporarily improving, but an appendicitis requiring surgery. The surgical specimen showed a 6cm mass on the back of the cecum. This tumor was diagnosed as appendiceal metastasis because the histology of carcinoma resembled the previous specimen from left lung cancer. Pathological findings showed poorly differentiated adenocarcinoma with abscess formation. Carcinoma mainly involves proper muscles and invades the mucosa and subserosa. He died of pneumonia 12 months after his last surgery. We discuss therapy for metastatic appendiceal tumor with appendicitis in cancer patients and review the literature.
Author Yamamoto, Masayoshi
Yanagisawa, Kazuhiko
Ohkouchi, Nobuhiro
Fukuzawa, Junya
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  fullname: Yanagisawa, Kazuhiko
  organization: Department of Surgery, Institute of Clinical Medicine, University of Tsukuba
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References 10) Nitecki SS, Wolff BG, Schlinkert R et al: The natural history of surgically treated primary adenocarcinoma of the appendix. Ann Surg 219: 51-57, 1994
5) Haid M, Larson R, Christ M: Metastasis from adenocarcinoma of the lung producing acute appendicitis. South Med J 85: 319-321, 1992
1) Dieter RA Jr: Carcinoma metastatic to the vermiform appendix: report of three cases. Dis Colon Rectum 13: 336-340, 1970
8) 大割貢, 岩瀬和裕, 檜垣淳ほか: 肺小細胞癌虫垂転移による急性虫垂炎の1例. 日腹部救急医会誌22: 827-830, 2002
3) 吉田淳, 岩佐真, 世古口務ほか: 肺癌虫垂転移による急性虫垂炎の1例. 日消外会誌14: 113-116, 1981
9) Goldstein EB, Savel RH, Walter KL et al: Extensive stage small cell lung cancer presenting as an acute perforated appendix: case report and review of the literature. Am Surg 70: 706-709, 2004
2) Zelikowski A, Urca I: Metastatic carcinoma of the appendix: report of a case. Dis Colon Rectum 15: 305-307, 1972
7) Gopez EV, Mourelatos Z, Rosato EF et al: Acute appendicitis secondary to metastatic bronchogenic adenocarcinoma. Am Surg 63: 778-780, 1997
4) Pang LC: Metastasis-induced acute appendicitis in small cell bronchogenic carcinoma. South Med J 81: 1461-1462, 1988
6) Gonzalez-Vela MC, Garcia-Valtuille AI, Fernandez FA et al: Metastasis from small cell carcinoma of the lung producing acute appendicitis. Pathol Int 46: 216-220, 1996
References_xml – reference: 5) Haid M, Larson R, Christ M: Metastasis from adenocarcinoma of the lung producing acute appendicitis. South Med J 85: 319-321, 1992
– reference: 1) Dieter RA Jr: Carcinoma metastatic to the vermiform appendix: report of three cases. Dis Colon Rectum 13: 336-340, 1970
– reference: 6) Gonzalez-Vela MC, Garcia-Valtuille AI, Fernandez FA et al: Metastasis from small cell carcinoma of the lung producing acute appendicitis. Pathol Int 46: 216-220, 1996
– reference: 10) Nitecki SS, Wolff BG, Schlinkert R et al: The natural history of surgically treated primary adenocarcinoma of the appendix. Ann Surg 219: 51-57, 1994
– reference: 7) Gopez EV, Mourelatos Z, Rosato EF et al: Acute appendicitis secondary to metastatic bronchogenic adenocarcinoma. Am Surg 63: 778-780, 1997
– reference: 8) 大割貢, 岩瀬和裕, 檜垣淳ほか: 肺小細胞癌虫垂転移による急性虫垂炎の1例. 日腹部救急医会誌22: 827-830, 2002
– reference: 3) 吉田淳, 岩佐真, 世古口務ほか: 肺癌虫垂転移による急性虫垂炎の1例. 日消外会誌14: 113-116, 1981
– reference: 4) Pang LC: Metastasis-induced acute appendicitis in small cell bronchogenic carcinoma. South Med J 81: 1461-1462, 1988
– reference: 9) Goldstein EB, Savel RH, Walter KL et al: Extensive stage small cell lung cancer presenting as an acute perforated appendix: case report and review of the literature. Am Surg 70: 706-709, 2004
– reference: 2) Zelikowski A, Urca I: Metastatic carcinoma of the appendix: report of a case. Dis Colon Rectum 15: 305-307, 1972
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Snippet We repossrt a case of appendiceal metastasis from lung cancer with acute appendicitis. A 65-year-old man underwent left pneumonectomy and mediastinum lymphnode...
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SubjectTerms acute appendicitis
appendiceal metastasis
lung cancer
Title A Case of Appendiceal Metastasis from Lung Cancer with Acute Appendicitis
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