Biological Evaluation of ChuangYuLing Dressing A Multifunctional Medicine Carrying Biomaterial
The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and...
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| Published in | Current medical science Vol. 25; no. 1; pp. 72 - 74 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
China
Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430022, China%Hubei Academy of Traditional Chinese Medicine and Pharmacy, Wuhan 430074, China%Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030, China
2005
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-0733 2096-5230 1993-1352 2523-899X |
| DOI | 10.1007/BF02831391 |
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| Abstract | The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China , the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing. |
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| AbstractList | The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China, the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing.The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China, the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing. The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China , the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing. R3; The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China[1] , the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing. |
| Author | 彭锐 郑启新 郝杰 邹阳 程杰 |
| AuthorAffiliation | DepartmentofOrthopedics,TongjiHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430030,China DepartmentofOrthopedics,UnionHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430022,China HubeiAcademyofTraditionalChineseMedicineandPharmacy,Wuhan430074,China |
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| Keywords | wound dressing biomaterial biological evaluation traditional Chinesemedicine gelatin-Bletilla hyacinthine gum |
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| References | H P Hao (BF02831391_CR1) 2000 P K Smith (BF02831391_CR5) 1985; 150 I V Yannas (BF02831391_CR6) 1980; 14 X P Zheng (BF02831391_CR2) 2000; 9 C J Kirkpatrick (BF02831391_CR9) 1998; 212 T Mosmann (BF02831391_CR4) 1983; 65 S Suzuki (BF02831391_CR8) 1990; 43 R F Oliver (BF02831391_CR7) 1982; 3 Q Chen (BF02831391_CR3) 1993 |
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| SubjectTerms | Animals ChuangYuLing Drugs, Chinese Herbal - administration & dosage Drugs, Chinese Herbal - toxicity Gelatin Guinea Pigs Occlusive Dressings Phytotherapy Rabbits Salvia miltiorrhiza Wound Healing - drug effects 中药制剂 伤口愈合 生物学评价 生物材料 |
| Title | Biological Evaluation of ChuangYuLing Dressing A Multifunctional Medicine Carrying Biomaterial |
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