Pandora's Box

Genes and neurodevelopment – the link A range of psychiatric diagnoses including schizophrenia, bipolar disorder, depression, autism and attention-deficit hyperactivity disorder (ADHD) are often observed within the same families as well as within individuals, and there is increasing evidence that th...

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Published inBJPsych international Vol. 16; no. 2; pp. 48 - 50
Format Journal Article
LanguageEnglish
Published Cambridge, UK Cambridge University Press 01.05.2019
Subjects
Archives & records
Attention deficit hyperactivity disorder
Autism
Autoimmune diseases
Bipolar disorder
Brain
Brain research
Cosmetics
Deoxyribonucleic acid
DNA
Dust
Endocrine disruptors
Epidemiology
Etiology
Genes
Genetic engineering
Genetics
Genomes
Health care
Healthy food
Insomnia
Literature reviews
Lymphocytes
Mental disorders
Mental health services
Milk
Neurons
Neurosciences
Pandora's Box
Pesticides
Psychiatric research
Schizophrenia
Sleep disorders
Smartphones
Thyroid gland
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ISSN2056-4740
2058-6264
DOI10.1192/bji.2019.7

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Abstract Genes and neurodevelopment – the link A range of psychiatric diagnoses including schizophrenia, bipolar disorder, depression, autism and attention-deficit hyperactivity disorder (ADHD) are often observed within the same families as well as within individuals, and there is increasing evidence that these conditions may share genetic aetiology. Researchers from the mental health services with the University of Copenhagen and the Lundbeck Foundation's Initiative for Integrated Psychiatric Research Consortium attempt to shed light on this question by examining the genetic determinants of fetal neurodevelopment in relation to psychiatric disorders. A recent thorough and extensive review of the literature on the subject of EDCs, from the University of Paris-Sorbonne, draws attention to epidemiological and experimental findings of the past decade, focusing on thyroid hormone-disrupting chemicals and their effects on brain development. EDCs are found not only in pesticides, flame-retardants and perfluorinated compounds, but also in furniture, plastic and in the manufacture of drugs, cosmetics and other materials, and can get into our bodies through food, water, dust and inhalation of gases and air particles, as well as through the skin and via breast milk.
AbstractList Genes and neurodevelopment – the link A range of psychiatric diagnoses including schizophrenia, bipolar disorder, depression, autism and attention-deficit hyperactivity disorder (ADHD) are often observed within the same families as well as within individuals, and there is increasing evidence that these conditions may share genetic aetiology. Researchers from the mental health services with the University of Copenhagen and the Lundbeck Foundation's Initiative for Integrated Psychiatric Research Consortium attempt to shed light on this question by examining the genetic determinants of fetal neurodevelopment in relation to psychiatric disorders. A recent thorough and extensive review of the literature on the subject of EDCs, from the University of Paris-Sorbonne, draws attention to epidemiological and experimental findings of the past decade, focusing on thyroid hormone-disrupting chemicals and their effects on brain development. EDCs are found not only in pesticides, flame-retardants and perfluorinated compounds, but also in furniture, plastic and in the manufacture of drugs, cosmetics and other materials, and can get into our bodies through food, water, dust and inhalation of gases and air particles, as well as through the skin and via breast milk.
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31144682$$D View this record in MEDLINE/PubMed
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Cites_doi 10.3233/JAD-180959
10.1038/s41593-018-0320-0
10.1038/s41467-019-08774-1
10.1530/EC-18-0029
10.1016/j.celrep.2018.11.008
10.1038/s41467-018-06590-7
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StartPage 48
SubjectTerms Archives & records
Attention deficit hyperactivity disorder
Autism
Autoimmune diseases
Bipolar disorder
Brain
Brain research
Cosmetics
Deoxyribonucleic acid
DNA
Dust
Endocrine disruptors
Epidemiology
Etiology
Genes
Genetic engineering
Genetics
Genomes
Health care
Healthy food
Insomnia
Literature reviews
Lymphocytes
Mental disorders
Mental health services
Milk
Neurons
Neurosciences
Pandora's Box
Pesticides
Psychiatric research
Schizophrenia
Sleep disorders
Smartphones
Thyroid gland
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