Creation of Database of Protocols for Dispensing and Preparation of Cancer Drugs and its Application
The results of cancer chemotherapy have been improved remarkably by the development of new drugs and combining drugs in treatment. However, cancer chemotherapy protocols are complicated and the adverse effects are more severe than those of other pharmacotherapies. It was therefore felt important to...
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| Published in | Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) Vol. 31; no. 7; pp. 575 - 584 |
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| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japanese Society of Pharmaceutical Health Care and Sciences
2005
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1346-342X 1882-1499 1882-1499 |
| DOI | 10.5649/jjphcs.31.575 |
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| Abstract | The results of cancer chemotherapy have been improved remarkably by the development of new drugs and combining drugs in treatment. However, cancer chemotherapy protocols are complicated and the adverse effects are more severe than those of other pharmacotherapies. It was therefore felt important to create a database of protocols for the preparation and dispensing of drugs used in cancer chemotherapy. Using Microsoft Access, we have created a database from 320 protocols we have collected so far from 12 clinical departments and developed operating programs for it. The database has enabled us to search for a protocol using keywords-names of drugs, diseases and clinical departments-and most of the operations can be carried out by the click of a mouse. With our database, pharmacists are able to access protocols quickly and check prescriptions of anticancer drugs even if they are unfamiliar with computers, and we consider it to be a useful tool for this purpose. |
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| AbstractList | The results of cancer chemotherapy have been improved remarkably by the development of new drugs and combining drugs in treatment. However, cancer chemotherapy protocols are complicated and the adverse effects are more severe than those of other pharmacotherapies. It was therefore felt important to create a database of protocols for the preparation and dispensing of drugs used in cancer chemotherapy. Using Microsoft Access, we have created a database from 320 protocols we have collected so far from 12 clinical departments and developed operating programs for it. The database has enabled us to search for a protocol using keywords-names of drugs, diseases and clinical departments-and most of the operations can be carried out by the click of a mouse. With our database, pharmacists are able to access protocols quickly and check prescriptions of anticancer drugs even if they are unfamiliar with computers, and we consider it to be a useful tool for this purpose. |
| Author | Mabuchi, Tomomi Takekuma, Yoh Miyazaki, Katsumi Ogino, Osamu Kumai, Masayoshi Kawagishi, Toru Iwai, Miwako Fujiwara, Toshie Suda, Noriyuki Miyamoto, Takenori Sugawara, Mitsuru Matsuura, Maya |
| Author_xml | – sequence: 1 fullname: Kumai, Masayoshi organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Mabuchi, Tomomi organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Takekuma, Yoh organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Miyamoto, Takenori organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Fujiwara, Toshie organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Iwai, Miwako organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Sugawara, Mitsuru organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Suda, Noriyuki organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Ogino, Osamu organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Miyazaki, Katsumi organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Kawagishi, Toru organization: Department of Pharmacy, Hokkaido University Hospital – sequence: 1 fullname: Matsuura, Maya organization: Department of Pharmacy, Hokkaido University Hospital |
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| References | 5) 熊岡穣, 伏見康子, 有澤幸大, 西口工司, 松林照久, 西庄京子, 栄田敏之, 西村善博, 横山光宏, 奥村勝彦, 癌化学療法に対する注射処方監査支援システムの構築と運用, 医療薬学, 29, 66-72 (2003). 1) 木村之彦, 急性白血病における最近の進歩, 癌と化学療法, 30,895-901 (2003). 2) J.H. Schiller, D. Harrington, C.P. Belani, C. Langer, A. Sandler, J. Krook, J. Zhu and D.H. Johnson, Comparison of four chemotherapy regimens for advanced nonsmall-cell lung cancer, N. Engl. J. Med., 346, 92-98 (2002). 3) J.P. Guastalla 3 rd, V. Dieras, The taxanes : toxicity and quality of life considerations in advanced ovarian cancer, Br. J. Cancer, 89, Suppl 3, S 16-22 (2003). 8) 和田淳, 村山佳子, 村上妙子, 大谷雅子, 中上達矢, 松本功三, 汎用ソフトを利用した抗悪性腫瘍剤の調製支援システムの構築とその評価, 日本病院薬剤師会雑誌, 38,167-169 (2002). 9) G. Visani, M.C. Petti, A. Cenacchi, S. Manfroi, P. Tosi, A. Spadea, R. Latagliata, S. Amadori, F. Mandelli and S. Tura, MEC (mitoxantrone, etoposide and intermediate dose cytarabine) : an effective induction regimen for previously untreated acute non-lymphocytic leukemia, Leuk Lymphoma, 19,447-451 (1995). 6) 尾上雅英, 高柳和伸, 國正淳一, 岡野友信, 橋田亨, 二見高弘, 山崎誠二, 今村正之, 乾賢一, 抗癌剤の適正使用への取り組み-薬剤部と腫瘍外科において-, 医療薬学, 25,321-326 (2002). 4) 井上博文, 大倉輝明, 中小病院における抗がん剤投与管理とその支援システムの構築, 日本病院薬剤師会雑誌, 39,197-200 (2003). 7) 下枝貞彦, 町田修一, 太田伸, 斉藤博, リスクマネジメントを目的とした癌化学療法プロトコール管理システムの開発, 医薬ジャーナル, 38, 3088-3096 (2002). 10) G.V. Dahl, N.J. Lacayo, N. Brophy, K. Dunussi-Joannopoulos, H.J. Weinstein, M. Chang, B.I. Sikic and R.J. Arceci, Mitoxantrone, etoposide, and cyclosporine therapy in pediatric patients with recurrent or refractory acute myeloid leukemia, J. Clin. Oncol., 18, 1867-1875 (2000). |
| References_xml | – reference: 10) G.V. Dahl, N.J. Lacayo, N. Brophy, K. Dunussi-Joannopoulos, H.J. Weinstein, M. Chang, B.I. Sikic and R.J. Arceci, Mitoxantrone, etoposide, and cyclosporine therapy in pediatric patients with recurrent or refractory acute myeloid leukemia, J. Clin. Oncol., 18, 1867-1875 (2000). – reference: 8) 和田淳, 村山佳子, 村上妙子, 大谷雅子, 中上達矢, 松本功三, 汎用ソフトを利用した抗悪性腫瘍剤の調製支援システムの構築とその評価, 日本病院薬剤師会雑誌, 38,167-169 (2002). – reference: 3) J.P. Guastalla 3 rd, V. Dieras, The taxanes : toxicity and quality of life considerations in advanced ovarian cancer, Br. J. Cancer, 89, Suppl 3, S 16-22 (2003). – reference: 5) 熊岡穣, 伏見康子, 有澤幸大, 西口工司, 松林照久, 西庄京子, 栄田敏之, 西村善博, 横山光宏, 奥村勝彦, 癌化学療法に対する注射処方監査支援システムの構築と運用, 医療薬学, 29, 66-72 (2003). – reference: 6) 尾上雅英, 高柳和伸, 國正淳一, 岡野友信, 橋田亨, 二見高弘, 山崎誠二, 今村正之, 乾賢一, 抗癌剤の適正使用への取り組み-薬剤部と腫瘍外科において-, 医療薬学, 25,321-326 (2002). – reference: 7) 下枝貞彦, 町田修一, 太田伸, 斉藤博, リスクマネジメントを目的とした癌化学療法プロトコール管理システムの開発, 医薬ジャーナル, 38, 3088-3096 (2002). – reference: 4) 井上博文, 大倉輝明, 中小病院における抗がん剤投与管理とその支援システムの構築, 日本病院薬剤師会雑誌, 39,197-200 (2003). – reference: 9) G. Visani, M.C. Petti, A. Cenacchi, S. Manfroi, P. Tosi, A. Spadea, R. Latagliata, S. Amadori, F. Mandelli and S. Tura, MEC (mitoxantrone, etoposide and intermediate dose cytarabine) : an effective induction regimen for previously untreated acute non-lymphocytic leukemia, Leuk Lymphoma, 19,447-451 (1995). – reference: 1) 木村之彦, 急性白血病における最近の進歩, 癌と化学療法, 30,895-901 (2003). – reference: 2) J.H. Schiller, D. Harrington, C.P. Belani, C. Langer, A. Sandler, J. Krook, J. Zhu and D.H. Johnson, Comparison of four chemotherapy regimens for advanced nonsmall-cell lung cancer, N. Engl. J. Med., 346, 92-98 (2002). |
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| Title | Creation of Database of Protocols for Dispensing and Preparation of Cancer Drugs and its Application |
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